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    Natural Products
    Ginsenoyne K
    Ginsenoyne K
    Information
    CAS No. 141947-42-4 Price
    Catalog No.CFN96044Purity>=98%
    Molecular Weight276.4Type of CompoundLipids
    FormulaC17H24O3Physical DescriptionOil
    Download     COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    Ginsenoyne K

    Ginsenoyne K
    Product Name Ginsenoyne K
    CAS No.: 141947-42-4
    Catalog No.: CFN96044
    Molecular Formula: C17H24O3
    Molecular Weight: 276.4 g/mol
    Purity: >=98%
    Type of Compound: Lipids
    Physical Desc.: Oil
    Targets: Tyrosinase
    Source: The herbs of Glehnia littoralis
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price:
    Inquire / Order: manager@chemfaces.com
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  • The Journal of Agromedicine and Medical Sciences2018, 4(1)
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Inhibitors Compound Library
  • Tyrosinase Inhibitor Library
  • Biological Activity
    Description: Ginsenoyne K shows dose-dependent inhibitory effect on dopa oxidase activity of tyrosinase.
    Targets: Tyrosinase
    In vitro:
    J Agric Food Chem. 2008 May 14;56(9):3024-7.
    Cytotoxic phenylpropanoids from carrot.[Pubmed: 18422328]
    Carrot is widely used as a foodstuff. The active components such as beta-carotene and panaxynol have been studied by many researchers.
    METHODS AND RESULTS:
    In this investigation of nonpolar active components from carrot, a new phenylpropanoid, epilaserine oxide ( 3), was isolated along with six known compounds, laserine ( 1), 2-epilaserine ( 2), panaxynol ( 4), Ginsenoyne K ( 5), (8 E)-1,8-heptadecadiene-4,6-diyne-3,10-diol ( 6), and vaginatin ( 7). Their structures were deduced on the basis of spectroscopic methods. Significant cytotoxicity of 2-epilaserine against HL-60 cells was observed, which implied that phenylpropanoids were cytotoxic compounds in carrot.
    CONCLUSIONS:
    Laserine and 2-epilaserine in carrots from diverse locations in China were quantified by HPLC.
    Ginsenoyne K Description
    Source: The herbs of Glehnia littoralis
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Cell. 2018 Jan 11;172(1-2):249-261.e12.
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    IF=36.216(2019)

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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.6179 mL 18.0897 mL 36.1795 mL 72.3589 mL 90.4486 mL
    5 mM 0.7236 mL 3.6179 mL 7.2359 mL 14.4718 mL 18.0897 mL
    10 mM 0.3618 mL 1.809 mL 3.6179 mL 7.2359 mL 9.0449 mL
    50 mM 0.0724 mL 0.3618 mL 0.7236 mL 1.4472 mL 1.809 mL
    100 mM 0.0362 mL 0.1809 mL 0.3618 mL 0.7236 mL 0.9045 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Natural Product Sciences, 2008 , 14 (3) :177-181.
    Polyacetylenes from the tissue cultured adventitious roots of Panax ginseng C.A. meyer[Reference: WebLink]

    METHODS AND RESULTS:
    Five polyacetylenes, Ginsenoyne K (1), (Z)-1-methoxyheptadeca-9-en-4,6-diyne-3-one (2), panaxydol (3), panaxydiol (4), and (E)-heptadeca-8-en-4,6-diyne-3,10-diol (5) were isolated from the adventitious roots of Panax ginseng and their chemical structures were elucidated by interpretation of spectroscopic data. Among the isolated compounds, compounds 2 and 5 were reported for the first time as a natural product.
    CONCLUSIONS:
    Ginsenoyne K (1) showed dose-dependent inhibitory effect on dopa oxidase activity of tyrosinase.
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