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    Natural Products
    Gomisin O
    Information
    CAS No. 72960-22-6 Price $338 / 10mg
    Catalog No.CFN90751Purity>=98%
    Molecular Weight416.46Type of CompoundLignans
    FormulaC23H28O7Physical DescriptionPowder
    Download     COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $219.7 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    Gomisin O

    Gomisin O
    Product Name Gomisin O
    CAS No.: 72960-22-6
    Catalog No.: CFN90751
    Molecular Formula: C23H28O7
    Molecular Weight: 416.46 g/mol
    Purity: >=98%
    Type of Compound: Lignans
    Physical Desc.: Powder
    Source: The fruits of Schizandra chinensis
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price: $338 / 10mg
    Inquire / Order: manager@chemfaces.com
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    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
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    Description: Gomisin O is a natural product from Schizandra chinensis.
    Gomisin O Description
    Source: The fruits of Schizandra chinensis
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.4012 mL 12.006 mL 24.0119 mL 48.0238 mL 60.0298 mL
    5 mM 0.4802 mL 2.4012 mL 4.8024 mL 9.6048 mL 12.006 mL
    10 mM 0.2401 mL 1.2006 mL 2.4012 mL 4.8024 mL 6.003 mL
    50 mM 0.048 mL 0.2401 mL 0.4802 mL 0.9605 mL 1.2006 mL
    100 mM 0.024 mL 0.1201 mL 0.2401 mL 0.4802 mL 0.6003 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Chemical & pharmaceutical bulletin 27(11), 2695-2709, 1979-11-25
    The Constituents of Schizandra chinensis BAILL. V. The Structures of Four New Lignans, Gomisin N, Gomisin O, Epigomisin O and Gomisin E, and Transformation of Gomisin N to Deangeloylgomisin B[Reference: WebLink]
    Four new dibenzocyclooctadiene lignans, gomisin N (1), Gomisin O (2) and gomisin E (4), and epiGomisin O (3), together with a known lignan (+)-deoxyschizandrin (5) were isolated from the fruits of Schizandra chinensis BAILL. (Schizandraceae).
    METHODS AND RESULTS:
    The structures of the new lignans were elucidated by chemical and spectral studies. The transformation of 1 to deangeloylgomisin B (debenzoylgomisin C) (6) is also described.
    J Org Chem. 2005 Oct 28;70(22):8932-41.
    Asymmetric total synthesis of dibenzocyclooctadiene lignan natural products.[Pubmed: 16238330 ]
    Full details of the asymmetric total syntheses of the dibenzocyclooctadiene lignans interiotherin A, angeloylgomisin R, Gomisin O, and gomisin E (epiGomisin O) are presented.
    METHODS AND RESULTS:
    The syntheses were based on a unified synthetic strategy involving a novel crotylation using the Leighton auxiliary that occurred with excellent asymmetric induction (>98:2 enantiomeric ratio), a diastereoselective hydroboration/Suzuki-Miyaura coupling reaction sequence, and an atropdiastereoselective biarylcuprate coupling, both of which occurred with total (>20:1) stereocontrol. The syntheses were achieved in six to eight steps from simple aromatic precursors.
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