ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
How to Order
Orders via your E-mail:
1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
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Order & Inquiry & Tech Support
Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
Delivery & Payment method
1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
2. We accept: Wire transfer & Credit card & Paypal & Western Union
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $204.7 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
FEBS Lett.2015, 589(1):182-7J Chromatogr B Analyt Technol Bio...2017...Sci Rep.2017, 7:467-479Nutrients.2018, 10(12):E1998BMC Plant Biol.2018, 18(1):122BMC Complement Altern Med....2018...Nat Prod Sci.2018, 24(2):109-114Anticancer Res.2018, 38(4):2127-2135
The Japan Society for Analytical ...2018...Phytother Res.2019, 33(3):676-689Anal Sci.2019, 35(12):1317-1325Journal of Third Military Medical...2019...Phytomedicine.2019, 67:153159Sci Rep.2019, 9(1):6429Appl. Sci.2020, 10,1304Dent Mater J.2020, 39(4):690-695
Metabolites.2020, 11(1):E11.Oncol Lett.2020, 20(4):122.Evid Based Complement Alternat Me...2020...Oxid Med Cell Longev....2020...Molecules.2020, 25(15):3353.Molecules.2020, 25(21):5087. J Ethnopharmacol.2020, 254:112733.
Our products had been exported to the following research institutions and universities, And still growing.
University of Otago (New Zealand)Kyung Hee University (Korea)University of East Anglia (United Kingdom)Cancer Research Initatives Foun... (Malaysia)
Lodz University of Technology (Poland)Universit?t Basel (Switzerland)Regional Crop Research Institute (Korea)University of Hawaii Cancer Center (USA)
University of Fribourg (Switzerland)Korea Institute of Oriental Med... (Korea)Universita' Degli Studi Di Cagl... (Italy)
Inquire / Order:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Asian J Beauty Cosmetol2019, 17(3):287-294Chem Biol Interact.2016, 260:168-175Phytother Res.2019, 33(3):676-689Food Chem. 2020, 320:126530Biomol Ther (Seoul).2020, 28(6):542-548.Journal of Third Military Medical University2019, 41(2):110-115Molecules.2020, 25(21):5091.Asian J of Pharmaceutical&Clinical 2018, 11(2)Asian Journal of Chemistry2014, 26(22):7811-7816Pak J Pharm Sci.2019, 32(6):2879-2885
Related Screening Libraries
||Grosvenorine exhibits good antibacterial and antioxidant activities, with its metabolites possessing more potent activities, intestinal bacteria play an important role in the gastrointestinal metabolism of grosvenorine and significantly affect its pharmacological activities. |
|Chem Biodivers. 2015 Nov;12(11):1652-64. |
|The Gastrointestinal Tract Metabolism and Pharmacological Activities of Grosvenorine, a Major and Characteristic Flavonoid in the Fruits of Siraitia grosvenorii.[Pubmed: 26567944 ]|
|Grosvenorine is the major flavonoid compound of the fruits of Siraitia grosvenorii (Swingle) C. Jeffrey, a medical plant endemic to China.|
METHODS AND RESULTS:
In the present study, for the first time, the Grosvenorine metabolism in an in vitro simulated human gastrointestinal tract (including artificial gastric juice, artificial intestinal juice and intestinal flora), as well as its pharmacological activities (including anti-complement, antibacterial and antioxidant activities), was investigated. The results showed that Grosvenorine was metabolized by human intestinal flora; its four metabolites were isolated by semi-preparative HPLC and identified by NMR as kaempferitrin, afzelin, α-rhamnoisorobin, and kaempferol. Further pharmacological evaluation showed that Grosvenorine exhibited good antibacterial and antioxidant activities, with its metabolites possessing more potent activities. Although Grosvenorine did not present obvious anticomplement activity, its metabolites showed interesting activities.
This study revealed that intestinal bacteria play an important role in the gastrointestinal metabolism of Grosvenorine and significantly affect its pharmacological activities.
||The fruits of Siraitia grosuenorii
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.