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|Size /Price /Stock
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More articles cited ChemFaces products.
BMC Complement Altern Med.2014, 14:242Ind Crops Prod.2014, 62:173-178Fitoterapia.2015, 100:179-86J-STAGE2015, 249-255Pharm Biol.2016, 54(7):1255-62Planta Med.2016, 82(13):1208-16J Pharm Biomed Anal.2018, 151:32-41Food Quality and Safety2018, 2:213-219
Evid Based Complement Alternat Me...2018...Primary and Industrial.2018, 52(11)J of Health Science and Alternati...2019...Analytical methods2019, 11(6)J Pharm Biomed Anal.2019, 164:119-127Chemistry of Plant Materials....2019...Chemistry of Vegetable Raw Materi...2019...Anal Sci.2019, 35(12):1317-1325
Int J Cosmet Sci.2019, 41(1):12-20Aquaculture2019, 510:392-399J Sep Sci.2020, 201901140Food Res Int.2020, 133:109130.Phytother Res.2020, 34(4):788-795.Appl. Sci.2021, 11(1),14.J Nat Med.2021, doi: 10.1007.
Our products had been exported to the following research institutions and universities, And still growing.
University of Vienna (Austria)Max Rubner-Institut (MRI) (Germany)Uniwersytet Jagielloński w Kra... (Poland)Semmelweis Unicersity (Hungary)
Charles Sturt University (Denmark)MTT Agrifood Research Finland (Finland)Regional Crop Research Institute (Korea)Massachusetts General Hospital (USA)
S.N.D.T. Women's University (India)Universidade da Beira Interior (Germany)Seoul National University (Korea)
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Biochem Biophys Res Commun.2018, 505(1):194-200ACS Synth Biol.2020, 9(9):2282-2290.Int J Mol Sci.2018, 19(2)Nutrients.2018, 10(10)United States Patent Application2020, 20200038363Journal of Physiology & Pathology in Korean Medicine.2018, 32(2): 106-112Evid Based Complement Alternat Med.2020, 2020:8582318.Org Biomol Chem.2017, 15(31):6483-6492Biochem Biophys Res Commun.2020, 522(1):40-46Universite de Bordeaux2017, 2017BORD0867
Related Screening Libraries
||Homovanillic acid is used as a reagent to detect oxidative enzymes, and is associated with dopamine levels in the brain. Abnormalities in white matter were associated with low CSF Homovanillic acid.|
|Clin Chim Acta. 2013 Sep 23;424:253-7. |
|Analysis of vanillylmandelic acid and homovanillic acid by UPLC-MS/MS in serum for diagnostic testing for neuroblastoma.[Pubmed: 23830883]|
|Vanillylmandelic acid (VMA) and Homovanillic acid (HVA) are typically measured in urine for the diagnosis and monitoring of neuroblastoma, a tumor in children <5 y. A protocol for evaluation of serum VMA and Homovanillic acid has been utilized at our institution for approximately 25 y, originally validated using high performance liquid chromatography (HPLC) with an electrochemical detector.
We recently validated a serum VMA/HVA method by ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS).|
METHODS AND RESULTS:
After solvent extraction and clean up with Ultrafree centrifugal filters, samples were analyzed by UPLC-MS/MS in multiple reaction monitoring mode. The assay was linear between 2 and 1000 ng/ml for VMA and Homovanillic acid . Within run and run to run CVs were <5% for VMA at all levels, <10% for HVA at high levels, and <20% at low levels. Correlation with the HPLC method was acceptable with a constant bias. The reference interval for VMA by UPLC-MS/MS was determined to be ≤20 ng/ml, and HVA≤30 ng/ml. Original patient data comparing urine to serum showed diagnostic agreement >80% for both VMA and Homovanillic acid .
Correlation of VMA and Homovanillic acid was acceptable after adjustment of reference intervals. Collection of a single serum sample instead of 24-h urine collection saves time and improves accuracy of measurement due to difficulty of collecting a 24-h urine sample in infants and young children. UPLC-MS/MS also offers improved analyte specificity, improved signal to noise, and rapid analysis time.
|Dev Med Child Neurol. 2013 Jun;55(6):559-66. |
|Homovanillic acid in cerebrospinal fluid of 1388 children with neurological disorders.[Pubmed: 23480488]|
|To determine the prevalence of dopaminergic abnormalities in 1388 children with neurological disorders, and to analyse their clinical, neuroradiological, and electrophysiological characteristics.
METHODS AND RESULTS:
We studied biogenic amines in 1388 cerebrospinal fluid (CSF) samples from children with neurological disorders (mean age 3y 10mo, SD 4y 5mo; 712 males, 676 females. Correlations among CSF Homovanillic acid (HVA) values and other biochemical, clinical, neuroradiological, and electrophysiological parameters were analysed. Twenty-one patients with primary dopaminergic deficiencies were identified. Of the whole sample, 20% showed altered Homovanillic acid. We report neurological diseases with abnormal CSF Homovanillic acid values such as pontocerebellar hypoplasia, perinatal asphyxia, central nervous system infections, mitochondrial disorders, and other genetic diseases. Overlapping Homovanillic acid levels between primary and secondary dopamine deficiencies were observed. Prevalence of low CSF Homovanillic acid levels was significantly higher in neonatal patients (χ(2) =84.8, p<0.001). Abnormalities in white matter were associated with low CSF Homovanillic acid (odds ratio 2.3, 95% confidence interval 1.5-3.5).
HVA abnormalities are observed in various neurological diseases, but some are probably an unspecific finding. No clear limits for CSF Homovanillic acid values pointing towards primary diseases can be stated. We report several neurological diseases showing Homovanillic acid alterations. No neuroimaging traits were associated with low Homovanillic acid values, except for white matter abnormalities.
Homovanillic acid Description
||The barks of Ilex rotunda Thunb.
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Spectrochim Acta A Mol Biomol Spectrosc. 2014 Jan 24;118:1068-74. |
|Molecular structure and spectroscopic analysis of homovanillic acid and its sodium salt--NMR, FT-IR and DFT studies.[Pubmed: 24161870]|
|The estimation of the electronic charge distribution in metal complex or salt allows to predict what kind of deformation of the electronic system of ligand would undergo during complexation. It also permits to make more precise interpretation of mechanism by which metals affect the biochemical properties of ligands.
METHODS AND RESULTS:
Theinfluence ofsodium cation on the electronic system of Homovanillic acid was studied in this paper. Optimized geometrical structures of studied compounds were calculated by B3LYP/6-311++G(**) method. Mulliken, MK and ChelpG atomic charges were analyzed. The theoretical NMR and IR spectra were obtained. (1)H and (13)C NMR as well as FT-IR and FT-Raman spectra of studied compounds were also recorded and analyzed. The calculated parameters are compared with experimental characteristics of these molecules.