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    Natural Products
    Isosalvianolic acid C
    Information
    CAS No. 142115-17-1 Price
    Catalog No.CFN92565Purity>=98%
    Molecular Weight492.4Type of CompoundPhenylpropanoids
    FormulaC26H20O10Physical DescriptionPowder
    Download Manual    COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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    Isosalvianolic acid C

    Isosalvianolic acid C
    Product Name Isosalvianolic acid C
    CAS No.: 142115-17-1
    Catalog No.: CFN92565
    Molecular Formula: C26H20O10
    Molecular Weight: 492.4 g/mol
    Purity: >=98%
    Type of Compound: Phenylpropanoids
    Physical Desc.: Powder
    Targets: LDL
    Source: The herbs of Tournefortia sarmentosa.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Price:
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  • Universidade Estadual Paulista2017, 11449
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  • Biological Activity
    Description: Isosalvianolic acid C exhibits more potent activity than probucol except for salvianolic acid F .
    Targets: LDL
    Isosalvianolic acid C Description
    Source: The herbs of Tournefortia sarmentosa.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.0309 mL 10.1543 mL 20.3087 mL 40.6174 mL 50.7717 mL
    5 mM 0.4062 mL 2.0309 mL 4.0617 mL 8.1235 mL 10.1543 mL
    10 mM 0.2031 mL 1.0154 mL 2.0309 mL 4.0617 mL 5.0772 mL
    50 mM 0.0406 mL 0.2031 mL 0.4062 mL 0.8123 mL 1.0154 mL
    100 mM 0.0203 mL 0.1015 mL 0.2031 mL 0.4062 mL 0.5077 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    J Nat Prod. 2002 May;65(5):745-7.
    Anti-lipid-peroxidative principles from Tournefortia sarmentosa.[Pubmed: 12027757]

    METHODS AND RESULTS:
    Using the inhibition of Cu(2+)-induced low-density-lipoprotein (LDL) peroxidation to direct fractionation, four new benzenoids, tournefolal (1), tournefolic acids A (2) and B (3), and B ethyl ester (4), together with salvianolic acid A (5), Isosalvianolic acid C (6), lithospermic acid (7), salvianolic acid F (8), and rosmarinic acid (9), were isolated from the stems of Tournefortia sarmentosa. The structures of the new compounds 1-4 were elucidated on the basis of spectral and chemical methods. Furthermore, the anti-LDL-peroxidative activity of the isolated compounds was determined.
    CONCLUSIONS:
    All isolated compounds exhibited more potent activity than probucol except for salvianolic acid F (8).
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