ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
Citing Use of our Products
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Br J Pharmacol.2016, 173(2):396-410J Ethnopharmacol.2017, 198:87-90Mol Cell.2017, 68(4):673-685Int. J. of Food Properties...2017...Nutrients.2018, 10(10)J Hematol Oncol.2018, 11(1):112Sci Rep. 2018, 1-9Korean J of Medicinal Crop Scienc...2018...
Food Chem.2018, 262:78-85Oncology Letters2018, 4690-4696Korean Journal of Pharmacognosy...2018...J of Health Science and Alternati...2019...J Nat Sc Biol Med2019, 10(2):149-156Pharmacognosy Journal...2019...Enzyme Microb Technol.2019, 122:64-73Anal Sci.2019, 35(12):1317-1325
Int Immunopharmacol.2019, 71:22-31J Cell Physiol.2020, 10.1002Molecules2020, 25(4):892Molecules.2020 ,25(16):3697.Int J Mol Sci.2020, 21(22):8816. Int J Mol Sci.2020, 21(24):9369.Pharmacol Rep.2020, 72(2):472-480.
Our products had been exported to the following research institutions and universities, And still growing.
St. Jude Children Research Hosp... (USA)Utah State University (USA)University of Illinois (USA)Max-Planck-Insitut (Germany)
Macau University of Science and... (China)Korea Food Research Institute(K... (Korea)Universidad de Buenos Aires (Argentina)University of Wisconsin-Madison (USA)
Colorado State University (USA)University of Padjajaran (Indonesia)The Institute of Cancer Research (United Kingdom)
Related Screening Libraries
|Size /Price /Stock
||10 mM * 100 uL in DMSO / Inquiry / In-stock |
10 mM * 1 mL in DMSO / Inquiry / In-stock
||Triterpenoids Compound Library
|| Kuguacin N has antioxidant activity.|
Kuguacin N Description
||The fruits of Momordica charantia
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Scientia Agricultura Sinica, 2017. |
|Saponion Profiles and Antioxidant Activity,α-Glucosidase Inhibitory Activity of Momordica charantia of Different Varieties[Reference: WebLink]|
The content and composition of saponion of 13 different M. charantia varieties as well as the antioxidant activity and inhibitory effect of α-glucosidase were studied. |
METHODS AND RESULTS:
Perchloric acid-vanilin-glacial method was used to determine saponin content, while HPLC method was used to measure the contents of 7 saponin components. In addition, their antioxidant activity was evaluated by oxygen radical absorbance capacity (ORAC). The 4-nitrophenyl-2-β-D-glucopyranoside method was used to measure the a-glucosidase inhibitory activity and to analyze the relationship between the components and the corresponding activity. There is a significant difference in contents of saponin in 13 different varieties of M charantia.The content ranges of saponin were 0.52-1.20 g/100g DW, with an average value being 0.79 g/100g DW, and the coefficient of variability being 21.65%. The average contents of components were as follows: momorcharaside A 5.32 μg•g⁻¹ DW, momordicoside A 25.42 (μg•g⁻¹ DW, karaviloside XI 3.96 μg•g⁻¹ DW, momordicoside F2 66.95 μg•g⁻¹ DW, momordicoside K 183.70 μg•g⁻¹ DW, (23E)-3p,7p,25-trihydroxycucubita-5,23-dien-19-al 40.13 μg•g⁻¹ DW, and Kuguacin N 3.87 μg•g⁻¹ DW. ORAC values of the 13 M. charantia varieties varied from 2 747.76 to 15 584.07 μmol Trolox•g⁻¹, the average value being 8 879.48 mol Trolox•g⁻¹, the coefficient of variability being 34.91% and the IC50 value of alpha glucosidase varied from 1.55 to 4.96 mg•mL⁻¹.
Significant differences in the components of saponin and the antioxidant activity and the inhibitory effect on α-glucosidase of different varieties of M. charantia were detected. Saponin is the main active basis of a-glucosidase activity in M. charantia, but not the main antioxidant substance. (23E)-3p,7p,25-trihydroxycucubita-5,23-dien-19-al is the major active compound.