Info: More News
Science | Nature | Cell | View More
Natural Products
L-Quebrachitol
L-Quebrachitol
Information
CAS No. 642-38-6 Price
Catalog No.CFN90586Purity>=98%
Molecular Weight194.18Type of CompoundMiscellaneous
FormulaC7H14O6Physical DescriptionPowder
Download COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
Citing Use of our Products
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Sent to Email: info@chemfaces.com
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Fax: (0086)-27-84254680
E-mail: manager@chemfaces.com
Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal & Western Union
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Mendel University in Brno (Czech Republic)
  • Cornell University (USA)
  • Sanford Burnham Medical Researc... (USA)
  • Periyar University (India)
  • Yale University (USA)
  • St. Jude Children Research Hosp... (USA)
  • Imperial College London (United Kingdom)
  • University of Toulouse (France)
  • VIB Department of Plant Systems... (Belgium)
  • Sant Gadge Baba Amravati Univer... (India)
  • University of Brasilia (Brazil)
  • More...
  • Package
    Featured Products
    meso-Hannokinol

    Catalog No: CFN90864
    CAS No: N/A
    Price: $368/5mg
    Dictamnine

    Catalog No: CFN99783
    CAS No: 484-29-7
    Price: $40/20mg
    Ganoderic acid DM

    Catalog No: CFN99815
    CAS No: 173075-45-1
    Price: $318/5mg
    Butyrospermol

    Catalog No: CFN92376
    CAS No: 472-28-6
    Price: $388/5mg
    Picroside III

    Catalog No: CFN99567
    CAS No: 64461-95-6
    Price: $138/20mg
    Acetylshikonin

    Catalog No: CFN90308
    CAS No: 54984-93-9
    Price: $338/20mg
    Eleutheroside E

    Catalog No: CFN99984
    CAS No: 39432-56-9
    Price: $50/20mg

    L-Quebrachitol

    L-Quebrachitol
    Product Name L-Quebrachitol
    CAS No.: 642-38-6
    Catalog No.: CFN90586
    Molecular Formula: C7H14O6
    Molecular Weight: 194.18 g/mol
    Purity: >=98%
    Type of Compound: Miscellaneous
    Physical Desc.: Powder
    Source: The barks of Aspidosperma desmanthum
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Price:
    Download: COA    MSDS    SDF
    Similar structural: Comparison (Web)  (SDF)
    Inquire / Order: manager@chemfaces.com
    Technical Inquiries: service@chemfaces.com
    Tel: +86-27-84237783
    Fax: +86-27-84254680

    Address:
    1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
    product package
  • Kor. J. Herbol.2022, 37(5): 89-96.
  • J Breast Cancer.2015, 18(2):112-118
  • Molecules 2021, 26(4),1092.
  • Academic J of Second Military Medical University2019, 40(1)
  • Food Quality and Safety2018, 2:213-219
  • Food Science and Biotechnology2022, 10.1007.
  • Korean Herb. Med. Inf.2020, 8(2):233-242.
  • Bio-protocol2018, 9(14):e3301
  • Korean j.of Pharm.2017, 70-76
  • Phytomedicine.2019, 57:95-104
  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
    Biological Activity
    Description: L-Quebrachitol can as a sugar substitute for diabetics. Administration of sea buckthorn juice enriched in L-quebrachitol can increase fasting insulin level in plasma and show similar effects on random blood glucose level, glucose tolerance and the pancreatic tissue as observed for pure sea buckthorn juice.
    In vivo:
    Journal of Functional Foods, 2015 ,16 :223-233.
    Effects of sea buckthorn (Hippophaë rhamnoides) juice and L-quebrachitol on type 2 diabetes mellitus in db/db mice[Reference: WebLink]
    To study the effects of sea buckthorn juice and L-Quebrachitol on type 2 diabetes, db/db mice were given 10-week gavage administration of pure sea buckthorn juice or sea buckthorn juice enriched with L-Quebrachitol.
    METHODS AND RESULTS:
    Treatment with sea buckthorn juice reduced the feed intake, body weight gain, random blood glucose level, and the expression of insulin receptor β in the liver. Sea buckthorn juice significantly improved glucose tolerance and the integrity of pancreatic tissue. Administration of sea buckthorn juice enriched in L-Quebrachitol increased fasting insulin level in plasma and showed similar effects on random blood glucose level, glucose tolerance and the pancreatic tissue as observed for pure sea buckthorn juice.
    CONCLUSIONS:
    The results suggest hypoglycaemic effects of sea buckthorn juice in type 2 diabetic db/db mice, likely associated with improvement of pancreas and reversal of insulin resistance. L-Quebrachitol present in sea buckthorn might have contributed to the effects observed.
    L-Quebrachitol Description
    Source: The barks of Aspidosperma desmanthum
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    ChemFaces New Products and Compounds
    Cordifolioside A

    Catalog No: CFN95040
    CAS No: 155179-20-7
    Price: $318/10mg
    Decuroside I

    Catalog No: CFN95004
    CAS No: 96638-79-8
    Price: $318/5mg
    4'-Hydroxy-3',5,5',6,7,8-hexametho...

    Catalog No: CFN95407
    CAS No: 85644-03-7
    Price: $318/5mg
    Bocconoline

    Catalog No: CFN95373
    CAS No: 32906-88-0
    Price: $413/5mg
    Ephedrannin D1

    Catalog No: CFN95547
    CAS No: 1592431-55-4
    Price: $318/5mg
    Jacquilenin

    Catalog No: CFN95434
    CAS No: 7726-34-3
    Price: $318/5mg
    Peucenidin

    Catalog No: CFN95272
    CAS No: 33044-93-8
    Price: $318/5mg
    Corymboside

    Catalog No: CFN95292
    CAS No: 73543-87-0
    Price: $318/10mg
    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 5.1499 mL 25.7493 mL 51.4986 mL 102.9972 mL 128.7465 mL
    5 mM 1.03 mL 5.1499 mL 10.2997 mL 20.5994 mL 25.7493 mL
    10 mM 0.515 mL 2.5749 mL 5.1499 mL 10.2997 mL 12.8747 mL
    50 mM 0.103 mL 0.515 mL 1.03 mL 2.0599 mL 2.5749 mL
    100 mM 0.0515 mL 0.2575 mL 0.515 mL 1.03 mL 1.2875 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Carbohydr Res. 2008 Oct 13;343(15):2699-700.
    First record of L-quebrachitol in Allophylus edulis (Sapindaceae).[Pubmed: 18715552]
    Allophylus edulis, commonly called 'Chal chal', is a member of the Sapindaceae occurring in the Uruguayan and Brazilian native flora.
    METHODS AND RESULTS:
    During the phytochemical analysis of two Chal chal specimens from two well-differentiated geographical zones (Assis, São Paulo, Brazil, and Santa Lucía, Canelones, Uruguay), considerable amounts of L-Quebrachitol were isolated from both samples. The isolation was carried out from the ethanolic twig extracts obtained by maceration of both vegetal samples. White easily distinguishable crystals were mechanically separated, washed, and characterized by 1D and 2D NMR experiments and by MS data.
    CONCLUSIONS:
    Such techniques confirmed that the crystals isolated from sources collected in both countries resulted in the same compound, L-Quebrachitol, a natural product not previously reported for this species and one that has been investigated as a sugar substitute for diabetics. Worthy of note, the content of L-Quebrachitol in A. edulis may be the chemical basis to explain its ethnobotanical uses, since infusions of this plant are used to treat diabetes in the practice of local traditional medicine.
    meso-Hannokinol

    Catalog No: CFN90864
    CAS No: N/A
    Price: $368/5mg
    Dictamnine

    Catalog No: CFN99783
    CAS No: 484-29-7
    Price: $40/20mg
    Ganoderic acid DM

    Catalog No: CFN99815
    CAS No: 173075-45-1
    Price: $318/5mg
    Butyrospermol

    Catalog No: CFN92376
    CAS No: 472-28-6
    Price: $388/5mg
    Picroside III

    Catalog No: CFN99567
    CAS No: 64461-95-6
    Price: $138/20mg
    Acetylshikonin

    Catalog No: CFN90308
    CAS No: 54984-93-9
    Price: $338/20mg
    Eleutheroside E

    Catalog No: CFN99984
    CAS No: 39432-56-9
    Price: $50/20mg
    Tags: buy L-Quebrachitol | L-Quebrachitol supplier | purchase L-Quebrachitol | L-Quebrachitol cost | L-Quebrachitol manufacturer | order L-Quebrachitol | L-Quebrachitol distributor