ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
3. Inhibitors
Citing Use of our Products
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / $423.2 / In-stock |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
Forensic Sci Int.2022, 341:111475.Biomed Pharmacother.2019, 111:262-269Int Immunopharmacol.2022, 106:108603.Nat Prod Sci.2018, 24(3):206J Sci Food Agric.2017, 97(5):1656-1662Emirates Journal of Food and Agri...2022...Phytomedicine.2022, 110:154597.Eur J Pharmacol.2020, 889:173589.
Toxins (Basel).2020, 12(4):210. J Ethnopharmacol.2019, 241:112025Korean Herb. Med. Inf....2020...Cell Chem Biol.2019, 26(1):27-34PLoS One.2018, 13(3):e0193386J of Apicultural Research2020, 10.1080Int. J. Mol. Sci.2022, 23(14),7699; Food Chem.2019, 279:80-87
Molecules.2021, 26(19):6032.Molecules.2016, 21(6)Natural Product Communications...2020...Mol Med Rep.2015, 12(5):7789-95PLoS One.2017, 12(3):e0173585Trop J Nat Prod Res.2019, 3(1):6-9Nutrients.2018, 10(7)
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Our products had been exported to the following research institutions and universities, And still growing.
Korea Intitute of Science and T... (Korea)University of Ioannina (Greece)The University of Newcastle (Australia)Guangzhou Institutes of Biomedi... (China)
Semmelweis Unicersity (Hungary)Nanjing University of Chinese M... (China)Charles University in Prague (Czech Republic)Mendel University in Brno (Czech Republic)
Stanford University (USA)Imperial College London (United Kingdom)Johannes Gutenberg University M... (Germany)
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Buddlenoid A
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Process Biochemistry2019, 85:106-115Evid Based Complement Alternat Med.2021, 2021:6687513.Vietnam Journal of Science2022, 64(2), 69-75.J Nat Med.2021, doi: 10.1007.ACS Omega.2021, 6(36):23460-23474.Braz J Med Biol Res. 2016, 49(7)Chung Shan Medical University2020, US20200323790A1Metabolites2023, 13(1), 3.Oxid Med Cell Longev2020, 12ACS Pharmacol. Transl. Sci.2022, 5,7,479-490
Related Screening Libraries
| Description: |
Buddlenoid A shows high inhibition of mushroom tyrosinase. |
| Targets: |
Tyrosinase |
Buddlenoid A Description
| Source: |
The herbs of Aquilaria sinensis |
| Solvent: |
DMSO, Pyridine, Methanol, Ethanol, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
1.6821 mL |
8.4104 mL |
16.8209 mL |
33.6417 mL |
42.0521 mL |
| 5 mM |
0.3364 mL |
1.6821 mL |
3.3642 mL |
6.7283 mL |
8.4104 mL |
| 10 mM |
0.1682 mL |
0.841 mL |
1.6821 mL |
3.3642 mL |
4.2052 mL |
| 50 mM |
0.0336 mL |
0.1682 mL |
0.3364 mL |
0.6728 mL |
0.841 mL |
| 100 mM |
0.0168 mL |
0.0841 mL |
0.1682 mL |
0.3364 mL |
0.4205 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
| Kinase Assay: |
| Phytochemistry, 1992, 31(3):1075-1077. | | Two tyrosinase inhibiting flavonol glycosides from Buddleia coriacea.[Reference: WebLink] |
METHODS AND RESULTS:
Two new flavonol glycosides, Buddlenoid A and buddlenoid B, have been isolated and identified as tyrosinase inhibitors from the aerial parts of Buddleia coriacea. Their structures were deduced from spectroscopic evidence to be kaempferol 7-(6″-p-coumaroylglucoside) and isorhamnetin 7-(6″-p-coumaroylglucoside).
CONCLUSIONS:
Both buddlenoids showed high inhibition of mushroom tyrosinase. |
|
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