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Buddlenoid A
Buddlenoid A
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Buddlenoid A
Price: $368 / 5mg
CAS No.: 142750-32-1
Catalog No.: CFN95025
Molecular Formula: C30H26O13
Molecular Weight: 594.5 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Source: The herbs of Aquilaria sinensis
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $423.2 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Buddlenoid A shows high inhibition of mushroom tyrosinase.
Targets: Tyrosinase
Buddlenoid A Description
Source: The herbs of Aquilaria sinensis
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.6821 mL 8.4104 mL 16.8209 mL 33.6417 mL 42.0521 mL
5 mM 0.3364 mL 1.6821 mL 3.3642 mL 6.7283 mL 8.4104 mL
10 mM 0.1682 mL 0.841 mL 1.6821 mL 3.3642 mL 4.2052 mL
50 mM 0.0336 mL 0.1682 mL 0.3364 mL 0.6728 mL 0.841 mL
100 mM 0.0168 mL 0.0841 mL 0.1682 mL 0.3364 mL 0.4205 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Kinase Assay:
Phytochemistry, 1992, 31(3):1075-1077.
Two tyrosinase inhibiting flavonol glycosides from Buddleia coriacea.[Reference: WebLink]

METHODS AND RESULTS:
Two new flavonol glycosides, Buddlenoid A and buddlenoid B, have been isolated and identified as tyrosinase inhibitors from the aerial parts of Buddleia coriacea. Their structures were deduced from spectroscopic evidence to be kaempferol 7-(6″-p-coumaroylglucoside) and isorhamnetin 7-(6″-p-coumaroylglucoside).
CONCLUSIONS:
Both buddlenoids showed high inhibition of mushroom tyrosinase.
CFN925216-Hydroxykaempferol-3,6,7-triglucoside145134-62-9788.7C33H40O22
CFN911466-Hydroxykaempferol 3-O-beta-D-glucoside145134-61-8464.4C21H20O12
CFN958636-Hydroxykaempferol 7-glucoside70056-55-2464.4C21H20O12
CFN70347Eupalitin 3-galactoside35399-32-7492.4C23H24O12
CFN923716-Hydroxykaempferol 3,6-diglucoside142674-16-6626.5C27H30O17
CFN911476-Hydroxykaempferol 3-beta-rutinoside205527-00-0610.5C27H30O16
CFN925756-Hydroxykaempferol 3-Rutinoside -6-glucoside145134-63-0772.7C33H40O21
CFN80457Kaempferol-4'-O-beta-D-glucopyranoside52222-74-9448.38C21H20O11
CFN95145Rhamnocitrin 3-apiosyl-(1->2)-glucoside148031-68-9594.5C27H30O15
CFN951543-O-[5'''-O-feruloyl-beta-D-apiofuranosyl(1'''->2'')-beta-D-glucopyranosyl] rhamnocitrin148210-00-8770.7C37H38O18
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