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Latisxanthone C
Latisxanthone C
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Latisxanthone C
Price:
CAS No.: 197447-32-8
Catalog No.: CFN89046
Molecular Formula: C28H30O6
Molecular Weight: 462.54 g/mol
Purity: >=98%
Type of Compound: Xanthones
Physical Desc.: Powder
Source: The twigs of Garcinia nigrolineata.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Latisxanthone C shows inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells, it may be a valuable antitumor promoter.
In vitro:
Cancer Lett. 1998 Oct 23;132(1-2):113-7.
Xanthones as inhibitors of Epstein-Barr virus activation.[Pubmed: 10397461]

METHODS AND RESULTS:
To search for possible antitumor promoters, we carried out a primary screening of 20 xanthones isolated from plants of the Guttiferae family, using their possible inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells. Some of these xanthones, namely 1,3,7-trihydroxy-2-(3-methyl-2-butenyl)xanthone (8), dulxanthone B (10) and Latisxanthone C (15), were observed to significantly inhibit the EBV-EA activation.
CONCLUSIONS:
The investigation indicated that 8, 10 and 15 might be valuable antitumor promoters.
Latisxanthone C Description
Source: The twigs of Garcinia nigrolineata.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

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Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.162 mL 10.8099 mL 21.6198 mL 43.2395 mL 54.0494 mL
5 mM 0.4324 mL 2.162 mL 4.324 mL 8.6479 mL 10.8099 mL
10 mM 0.2162 mL 1.081 mL 2.162 mL 4.324 mL 5.4049 mL
50 mM 0.0432 mL 0.2162 mL 0.4324 mL 0.8648 mL 1.081 mL
100 mM 0.0216 mL 0.1081 mL 0.2162 mL 0.4324 mL 0.5405 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
CFN89058Parvifolixanthone A906794-56-7464.55C28H32O6
CFN89046Latisxanthone C197447-32-8462.54C28H30O6
CFN92696Butyraxanthone B1141754-81-5462.5C28H30O6
CFN92697Garcinone E112649-21-5464.6C28H32O6
CFN97125Isogarciniaxanthone E659747-28-1464.6 C28H32O6
CFN99816Garciniaxanthone E173294-74-1464.6 C28H32O6
CFN96575Sterigmatocystin10048-13-2324.29C18H12O6
CFN98089Griffipavixanthone219649-95-3652.6 C36H28O12
CFN96574Bijaponicaxanthone C872409-35-3670.62C36H30O13
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