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1. Reference standards
2. Pharmacological research
3. Inhibitors
(R)-O-isobutyroyllomatin
Citing Use of our Products
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / $351.1 / In-stock |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
Biomed Sci Letters.2020, 26:319-326Research on Crops.2017, 18(3):569Korean J Dent Mater.2018, 45(2):139-146Drug Invention Today...2019...Drug Chem Toxicol.2020, 1-12.Asian J of Pharmaceutical&Clinica...2018...Antioxidants (Basel).2020, 9(2):E120J Biochem Mol Toxicol....2020...
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Our products had been exported to the following research institutions and universities, And still growing.
Universidade Federal de Goias (... (Brazil)Medical University of Gdansk (Poland)Almansora University (Egypt)Osmania University (India)
Technical University of Denmark (Denmark)China Medical University (Taiwan)Universidade Católica Portuguesa (Portugal)Worcester Polytechnic Institute (USA)
Chinese University of Hong Kong (China)University of Melbourne (Australia)University of Liège (Belgium)
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(R)-O-isobutyroyllomatin
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manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Biochem Systematics and Ecology2017, 11-18Toxicol Appl Pharmacol.2021, 427:115668.Evid Based Complement Alternat Med.2021, 2021:5319584.iScience.2020, 23(2):100849.Molecules.2020, 25(11):2599. Analytical sci. & Tech2020, 33(5):224-231J of Health Science and Alternative Medicine2019, 1(1)Cells.2021, 10(11):2919. J Exp Bot.2016, 67(12):3777-88Food and Chemical Toxicology2020, 111221
Related Screening Libraries
| Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
|
Related Libraries |
Coumarins Compound Library |
| Description: |
(R)-O-isobutyroyllomatin shows significant dose-dependent protection against oxidative stress, it also exhibits cell proliferative effects. |
| In vitro: |
| Bioorganic & Medicinal Chemistry Letters, 18 May 2017, 27(14):3065-3070 | | Minor phenolics from Angelica keiskei and their proliferative effects on Hep3B cells.[Reference: WebLink] |
METHODS AND RESULTS:
A new coumarin, (-)-cis-(3'R,4'R)-4'-O-angeloylkhellactone-3'-O-β-d-glucopyranoside (1) and two new chalcones, 3'-[(2E)-5-carboxy-3-methyl-2-pentenyl]-4,2',4'-trihydroxychalcone (4) and (±)-4,2',4'-trihydroxy-3'-{2-hydroxy-2-[tetrahydro-2-methyl-5-(1-methylethenyl)-2-furanyl]ethyl}chalcone (5) were isolated from the aerial parts of Angelica keiskei (Umbelliferae), together with six known compounds: (R)-O-isobutyroyllomatin (2), 3'-O-methylvaginol (3), (-)-jejuchalcone F (6), isoliquiritigenin (7), davidigenin (8), and (±)-liquiritigenin (9). The structures of the new compounds were determined by interpretation of their spectroscopic data including 1D and 2D NMR data. All known compounds (2, 3, and 6-9) were isolated as constituents of A. keiskei for the first time. To identify novel hepatocyte proliferation inducer for liver regeneration, 1-9 were evaluated for their cell proliferative effects using a Hep3B human hepatoma cell line.
CONCLUSIONS:
All isolates exhibited cell proliferative effects compared to untreated control (DMSO). Cytoprotective effects against oxidative stress induced by glucose oxidase were also examined on Hep3B cells and mouse fibroblast NIH3T3 cells and all compounds showed significant dose-dependent protection against oxidative stress. |
|
(R)-O-isobutyroyllomatin Description
| Source: |
The herbs of Prionosciadium watsoni |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
3.1606 mL |
15.8028 mL |
31.6056 mL |
63.2111 mL |
79.0139 mL |
| 5 mM |
0.6321 mL |
3.1606 mL |
6.3211 mL |
12.6422 mL |
15.8028 mL |
| 10 mM |
0.3161 mL |
1.5803 mL |
3.1606 mL |
6.3211 mL |
7.9014 mL |
| 50 mM |
0.0632 mL |
0.3161 mL |
0.6321 mL |
1.2642 mL |
1.5803 mL |
| 100 mM |
0.0316 mL |
0.158 mL |
0.3161 mL |
0.6321 mL |
0.7901 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
