Info: Read More
  • Home
  • Natural Products
  • Bioactive
  • Screening Libraries
  • Hot Products
  • Plant Catalog
  • Customer Support
  • Product Use Citation
  • About Us
  • Contact Us
  • How to Order
  • Delivery time
  • Science | Nature | Cell | View More
    Natural Products
    (R)-O-isobutyroyllomatin
    (R)-O-isobutyroyllomatin
    Information
    CAS No. 440094-38-2 Price $413 / 5mg
    Catalog No.CFN95250Purity>=98%
    Molecular Weight316.4Type of CompoundCoumarins
    FormulaC18H20O5Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)  (SDF)
    Citing Use of our Products
    How to Order
    Orders via your E-mail:

    1. Product number / Name / CAS No.
    2. Delivery address
    3. Ordering/billing address
    4. Contact information
    Sent to Email: info@chemfaces.com
    Contact Us
    Order & Inquiry & Tech Support

    Tel: (0086)-27-84237683
    Fax: (0086)-27-84254680
    E-mail: manager@chemfaces.com
    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
    Delivery time
    Delivery & Payment method

    1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

    2. We accept: Wire transfer & Credit card & Paypal & Western Union
    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $351.1 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
  • Korea Intitute of Science and T... (Korea)
  • Heinrich-Heine-University Düss... (Germany)
  • Indian Institute of Science (India)
  • Colorado State University (USA)
  • Molecular Biology Institute of ... (Spain)
  • Ateneo de Manila University (Philippines)
  • University of Dicle (Turkey)
  • University of Medicine and Phar... (Romania)
  • Kyushu University (Japan)
  • Aarhus University (Denmark)
  • Wroclaw Medical University (Poland)
  • More...
  • Package
    Featured Products
    Isofebrifugine

    Catalog No: CFN92303
    CAS No: 32434-44-9
    Price: $488/20mg
    Morusinol

    Catalog No: CFN97086
    CAS No: 62949-93-3
    Price: $368/5mg
    Linderane

    Catalog No: CFN98175
    CAS No: 13476-25-0
    Price: $118/20mg
    Butyrospermol

    Catalog No: CFN92376
    CAS No: 472-28-6
    Price: $388/5mg
    Chrysin 6-C-arabinoside 8-C-glucos...

    Catalog No: CFN92284
    CAS No: 185145-33-9
    Price: $368/5mg
    Neochamaejasmine A

    Catalog No: CFN92151
    CAS No: 90411-13-5
    Price: $418/5mg
    Arteannuin B

    Catalog No: CFN98807
    CAS No: 50906-56-4
    Price: $228/20mg

    (R)-O-isobutyroyllomatin

    (R)-O-isobutyroyllomatin
    Product Name (R)-O-isobutyroyllomatin
    CAS No.: 440094-38-2
    Catalog No.: CFN95250
    Molecular Formula: C18H20O5
    Molecular Weight: 316.4 g/mol
    Purity: >=98%
    Type of Compound: Coumarins
    Physical Desc.: Powder
    Source: The herbs of Prionosciadium watsoni
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price: $413 / 5mg
    Inquire / Order: manager@chemfaces.com
    Technical Inquiries: service@chemfaces.com
    Tel: +86-27-84237783
    Fax: +86-27-84254680

    Address:
    1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
  • Molecules.2020 ,25(16):3697.
  • Foods.2020, 9(10):1348.
  • Naunyn Schmiedebergs Arch Pharmacol.2021, 394(1):107-115.
  • Exp Ther Med.2019, 18(6):4388-4396
  • Exp Biol Med (Maywood).2019, 244(16):1463-1474
  • Front Pharmacol.2016, 7:460
  • Phytomedicine.2019, 59:152785
  • Phytochem Anal.2016, 27(5):296-303
  • J Sci Food Agric.2018, 98(3):1153-1161
  • Int J Mol Med.2015, 35(5):1237-45
  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Coumarins Compound Library
  • Biological Activity
    Description: (R)-O-isobutyroyllomatin shows significant dose-dependent protection against oxidative stress, it also exhibits cell proliferative effects.
    In vitro:
    Bioorganic & Medicinal Chemistry Letters, 18 May 2017, 27(14):3065-3070
    Minor phenolics from Angelica keiskei and their proliferative effects on Hep3B cells.[Reference: WebLink]

    METHODS AND RESULTS:
    A new coumarin, (-)-cis-(3'R,4'R)-4'-O-angeloylkhellactone-3'-O-β-d-glucopyranoside (1) and two new chalcones, 3'-[(2E)-5-carboxy-3-methyl-2-pentenyl]-4,2',4'-trihydroxychalcone (4) and (±)-4,2',4'-trihydroxy-3'-{2-hydroxy-2-[tetrahydro-2-methyl-5-(1-methylethenyl)-2-furanyl]ethyl}chalcone (5) were isolated from the aerial parts of Angelica keiskei (Umbelliferae), together with six known compounds: (R)-O-isobutyroyllomatin (2), 3'-O-methylvaginol (3), (-)-jejuchalcone F (6), isoliquiritigenin (7), davidigenin (8), and (±)-liquiritigenin (9). The structures of the new compounds were determined by interpretation of their spectroscopic data including 1D and 2D NMR data. All known compounds (2, 3, and 6-9) were isolated as constituents of A. keiskei for the first time. To identify novel hepatocyte proliferation inducer for liver regeneration, 1-9 were evaluated for their cell proliferative effects using a Hep3B human hepatoma cell line.
    CONCLUSIONS:
    All isolates exhibited cell proliferative effects compared to untreated control (DMSO). Cytoprotective effects against oxidative stress induced by glucose oxidase were also examined on Hep3B cells and mouse fibroblast NIH3T3 cells and all compounds showed significant dose-dependent protection against oxidative stress.
    (R)-O-isobutyroyllomatin Description
    Source: The herbs of Prionosciadium watsoni
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    ChemFaces New Products and Compounds
    2-Methoxy-1,4-naphthoquinone

    Catalog No: CFN95269
    CAS No: 2348-82-5
    Price: $70/20mg
    Citrusin B

    Catalog No: CFN95178
    CAS No: 105279-10-5
    Price: $388/5mg
    8-Prenylnaringenin

    Catalog No: CFN92016
    CAS No: 53846-50-7
    Price: $138/10mg
    Glycycoumarin

    Catalog No: CFN89408
    CAS No: 94805-82-0
    Price: $268/10mg
    Bruceine E

    Catalog No: CFN89340
    CAS No: 21586-90-3
    Price: $318/20mg
    Physalin O

    Catalog No: CFN95097
    CAS No: 120849-18-5
    Price: $413/5mg
    Hastatoside

    Catalog No: CFN96588
    CAS No: 50816-24-5
    Price: $168/20mg
    Ganodermanontriol

    Catalog No: CFN99077
    CAS No: 106518-63-2
    Price: $413/5mg
    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.1606 mL 15.8028 mL 31.6056 mL 63.2111 mL 79.0139 mL
    5 mM 0.6321 mL 3.1606 mL 6.3211 mL 12.6422 mL 15.8028 mL
    10 mM 0.3161 mL 1.5803 mL 3.1606 mL 6.3211 mL 7.9014 mL
    50 mM 0.0632 mL 0.3161 mL 0.6321 mL 1.2642 mL 1.5803 mL
    100 mM 0.0316 mL 0.158 mL 0.3161 mL 0.6321 mL 0.7901 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Isofebrifugine

    Catalog No: CFN92303
    CAS No: 32434-44-9
    Price: $488/20mg
    Morusinol

    Catalog No: CFN97086
    CAS No: 62949-93-3
    Price: $368/5mg
    Linderane

    Catalog No: CFN98175
    CAS No: 13476-25-0
    Price: $118/20mg
    Butyrospermol

    Catalog No: CFN92376
    CAS No: 472-28-6
    Price: $388/5mg
    Chrysin 6-C-arabinoside 8-C-glucos...

    Catalog No: CFN92284
    CAS No: 185145-33-9
    Price: $368/5mg
    Neochamaejasmine A

    Catalog No: CFN92151
    CAS No: 90411-13-5
    Price: $418/5mg
    Arteannuin B

    Catalog No: CFN98807
    CAS No: 50906-56-4
    Price: $228/20mg