ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
How to Order
Orders via your E-mail:
1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Sent to Email: firstname.lastname@example.org
Order & Inquiry & Tech Support
Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
Delivery & Payment method
1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
2. We accept: Wire transfer & Credit card & Paypal & Western Union
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Cardiovasc Toxicol....2021...Biomed Chromatogr.2020, e5021.Metabolites.2020, 11(1):E11.Front Plant Sci.2021, 12:673337.J Sci Food Agric.2018, 98(3):1153-1161Green Chemistry2021, ISSUE 2.Antimicrob Agents Chemother....2020...Industrial Crops and Products...2020...
J Food Compos Anal2017, 62:197-204Indian J Pharm Sci.2022, 84(3):144-151Chem Biol Interact.2022, 368:110248. BMC Complement Altern Med....2019...Journal of Apicultural Research...2021...Pharmaceuticals (Basel)....2020...J Hematol Oncol.2018, 11(1):112Nutrients.2022, 14(19):4170.
Korean J. Food Preserv. ...2021...Nutrients.2018, 10(10)Integr Cancer Ther.2018, 17(3):832-843J Ethnopharmacol.2019, 244:112074Sci Rep.2019, 9(1):18080Nutrients.2017, 10(1)Nat Prod Sci.2014, 20(3):182-190
Our products had been exported to the following research institutions and universities, And still growing.
Lodz University of Technology (Poland)The University of Newcastle (Australia)Instituto de Investigaciones Ag... (Chile)Calcutta University (India)
Monash University (Australia)Fraunhofer-Institut für Moleku... (Germany)Universidade Federal de Santa C... (Brazil)Washington State University (USA)
Ain Shams University (Egypt)Weizmann Institute of Science (Israel)Donald Danforth Plant Science C... (USA)
Inquire / Order:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Evid Based Complement Alternat Med.2021, 2021:5023536.Int J Mol Sci.2022, 23(10):5813. Journal of Chromatography A2020, 460942Nature Ecology & Evolution2020, doi: 10.1038JAOCS2021, 98(7):779-794.Arch Toxicol.2017, 91(10):3225-3245Arch Biochem Biophys.2020, 687:108363.International Food Research Journal2018, 25(6):2560-2571Indian J Pharm Sci.2022, 84(3):144-151Nanjing University of Chinese Medicine2022, 345930.
Related Screening Libraries
|| Linderene acetate is a competitive inhibitor against Prolyl endopeptidase. |
Linderene acetate Description
||The roots of Lindera aggregata
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Biol Pharm Bull. 2002 Aug;25(8):1049-52. |
|Prolyl endopeptidase inhibitors from the roots of Lindera strychnifolia F. Vill.[Pubmed: 12186408]|
|Prolyl endopeptidase (PEP, EC 126.96.36.199) has been proposed to play a role in degradation of proline-containing neuropeptides involved in the processes of learning and memory, e.g., vasopressin, substance P, and thyrotropin-releasing hormone (TRH).
METHODS AND RESULTS:
In the course of our search for bioactive constituents in medicinal plants, we studied the PEP inhibitory constituents of the roots of Lindera strychnifolia F. VILL and isolated two known tannins, epicatechin (1) and aesculitannin B (2), and four known sesquiterpenes, linderene (3), Linderene acetate (4), linderalactone (5) and isolinderalactone (6) as inhibitors. On the inhibitory activities of six compounds against PEP from Flavobacterium meningosepticum and that from rat brain supernatant, compounds 1, 2 and 4 inhibited the enzyme from Flavobacterium more strongly than that from rat brain supernatant. However, compounds 3, 5 and 6 inhibited the enzymes from both origins to the same extent and furthermore, compound 6 was the strongest natural inhibitor against PEP from rat brain supernatant.
The kinetic study of these inhibitors indicated that compounds 1, 2 are noncompetitive inhibitors and compounds 3-6 are competitive inhibitors. This is the first example of non-phenolic constituents showing significant competitive inhibitory activity being isolated from natural medicines.