Science | Nature | Cell | View More
Natural Products
Magnolioside
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Magnolioside
Price: $268 / 10mg
CAS No.: 20186-29-2
Catalog No.: CFN90699
Molecular Formula: C16H18O9
Molecular Weight: 354.3 g/mol
Purity: >=98%
Type of Compound: Coumarins
Physical Desc.: Powder
Source: The herbs of Artemisia scoparia.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $148.1 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • University of Padjajaran (Indonesia)
  • Heidelberg University (Germany)
  • University of South Australia (Australia)
  • Aarhus University (Denmark)
  • University of British Columbia (Canada)
  • Universidad Industrial de Santa... (Colombia)
  • Anna University (India)
  • Centrum Menselijke Erfelijkheid (Belgium)
  • University of Amsterdam (Netherlands)
  • Massachusetts General Hospital (USA)
  • University of Canterbury (New Zealand)
  • More...
Package
Featured Products
Agnuside

Catalog No: CFN99203
CAS No: 11027-63-7
Price: $168/20mg
Cinnamic aldehyde

Catalog No: CFN90321
CAS No: 14371-10-9
Price: $30/20mg
Naringenin chalcone

Catalog No: CFN90606
CAS No: 73692-50-9
Price: $168/20mg
Platycoside E

Catalog No: CFN90786
CAS No: 237068-41-6
Price: $ / mg
Taxifolin

Catalog No: CFN98734
CAS No: 480-18-2
Price: $30/20mg
4-Hydroxybenzaldehyde

Catalog No: CFN99013
CAS No: 123-08-0
Price: $30/20mg
Scopolamine hydrobromide

Catalog No: CFN99709
CAS No: 114-49-8
Price: $30/20mg
1-Dehydro-10-gingerdione

Catalog No: CFN92374
CAS No: 136826-50-1
Price: $ / mg
Nodakenin

Catalog No: CFN90232
CAS No: 495-31-8
Price: $70/20mg
p-Hydroxy-cinnamic acid

Catalog No: CFN98179
CAS No: 7400-08-0
Price: $70/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Magnolioside has anti-plasmodial activity, shows notable growth inhibitory activity against chloroquine-sensitive strains of P. falciparum. It also shows a moderate antibacterial activity against Staphylococcus aureus CIP 53.154.
Targets: Antifection
In vitro:
Immunopharmacol Immunotoxicol. 2011 Dec;33(4):663-6.
Antiplasmodial and cytotoxic activity of coumarin derivatives from dried roots of Angelica gigas Nakai in vitro.[Pubmed: 21428713]
The butanol-soluble fraction of the dried root of Angelica gigas exhibited significant protection against chloroquine-sensitive strains of Plasmodium falciparum using the parasite lactate dehydrogenase assay method.
METHODS AND RESULTS:
Using antiplasmodial activity-guided fractionation, five coumarins, marmesinin (1), nodakenin (2), skimmin (3), apiosylskimmin (4), and Magnolioside (5), were isolated and evaluated for in vitro antiplasmodial activity, as well as for their cytotoxic potential on SK-OV-3 cancer cell lines. Compounds 1 and 5 showed notable growth inhibitory activity against chloroquine-sensitive strains of P. falciparum with IC(50) values of 5.3 and 8.2 μM. The compounds showed no significant cytotoxicity (IC(50) > 100 μM) toward the SK-OV-3 cancer cell line.
CONCLUSIONS:
This is the first report on the antiplasmodial activity of these coumarin derivatives from the dried root of A. gigas.
Phytochemistry Letters, 2016 , 18 :23-28.
Chemical composition, antibacterial, antioxidant and tyrosinase inhibitory activities of glycosides from aerial parts of Eryngium tricuspidatum L.[Reference: WebLink]
Two new phenolic glucosides, together with six known compounds, were isolated from the aerial part of Eryngium tricuspidatum L. (Apiaceae).
METHODS AND RESULTS:
The structures of the new compounds were established as 2-hydroxy- 3,5-dimethyl-acetophenon-4-O-β-d-glucopyranoside (1) and 2,3-dimethyl-4-hydroxymethylphenyl-1-hydroxymethyl-O-β-d-glucopyranoside (2) on the basis of detailed spectroscopic data including MS, 1D, and 2D NMR. The antibacterial, tyrosinase inhibitory and DPPH radical scavenging activities of hydromethanolic extract, fractions, and the eight isolated compounds were evaluated. The antibacterial assay showed a moderate activity for Magnolioside (4) against Staphylococcus aureus CIP 53.154. Compound 7 (quercetin 3-O-β-d-glucopyranosyl-(1 → 6)-O-β-d-galactopyranoside) had moderate DPPH radical scavenging activity whereas compounds 2 exhibited good inhibitory effect against mushroom tyrosinase.
Magnolioside Description
Source: The herbs of Artemisia scoparia.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
5-Hydroxy-7,8-dimethoxy (2R)-flava...

Catalog No: CFN95209
CAS No: 942626-74-6
Price: $318/10mg
Glyasperin C

Catalog No: CFN95065
CAS No: 142474-53-1
Price: $333/5mg
Silychristin B

Catalog No: CFN95160
CAS No: 879325-58-3
Price: $318/5mg
3-Oxo-alpha-ilexanolic acid

Catalog No: CFN95496
CAS No: N/A
Price: $413/5mg
Ganoderic acid GS-1

Catalog No: CFN95571
CAS No: 1206781-64-7
Price: $413/5mg
Gambogoic acid A

Catalog No: CFN95439
CAS No: 887923-49-1
Price: $318/10mg
Lathyranoic acid A

Catalog No: CFN95325
CAS No: 850560-44-0
Price: $318/5mg
Rebaudioside F

Catalog No: CFN95215
CAS No: 438045-89-7
Price: $268/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8225 mL 14.1123 mL 28.2247 mL 56.4493 mL 70.5617 mL
5 mM 0.5645 mL 2.8225 mL 5.6449 mL 11.2899 mL 14.1123 mL
10 mM 0.2822 mL 1.4112 mL 2.8225 mL 5.6449 mL 7.0562 mL
50 mM 0.0564 mL 0.2822 mL 0.5645 mL 1.129 mL 1.4112 mL
100 mM 0.0282 mL 0.1411 mL 0.2822 mL 0.5645 mL 0.7056 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Cell Research:
Arch Pharm Res. 2007 Nov;30(11):1368-73.
Neuroprotective coumarins from the root of Angelica gigas: structure-activity relationships.[Pubmed: 18087802]
An n-butanol-soluble fraction of the root of Angelica gigas Nakai (Umbelliferae) exhibited significant protection against glutamate-induced toxicity in primary cultured rat cortical cells.
METHODS AND RESULTS:
Using neuroprotective activity-guided fractionation, nine coumarins; marmesinin (1), nodakenin (2), columbianetin-O-beta-D-glucopyranoside (3), (S)-peucedanol-7-O-beta-D-glucopyranoside (4), (S)-peucedanol-3'-O-beta-D-glucopyranoside (5), skimmin (6), apiosylskimmin (7), isoapiosylskimmin (8) and Magnolioside (9), were isolated from the n-butanol fraction. Of these nine coumarins, three dihydrofuranocoumarins; 1, 2 and 3, exhibited significant neuroprotective activities against glutamate-induced toxicity, exhibiting cell viabilities of about 50% at concentrations ranging from 0.1 to 10 microM. To explore the structure-activity relationships of coumarins, sixteen previously isolated compounds; 10-25, were simultaneously evaluated in the same system.
CONCLUSIONS:
Our results revealed that cyclization of the isoprenyl group, such as dihydropyran or dihydrofuran, or the furan ring at the C-6 position of coumarin, as well as lipophilicity played an important role in the neuroprotective activity of coumarins.
Agnuside

Catalog No: CFN99203
CAS No: 11027-63-7
Price: $168/20mg
Cinnamic aldehyde

Catalog No: CFN90321
CAS No: 14371-10-9
Price: $30/20mg
Naringenin chalcone

Catalog No: CFN90606
CAS No: 73692-50-9
Price: $168/20mg
Platycoside E

Catalog No: CFN90786
CAS No: 237068-41-6
Price: $ / mg
Taxifolin

Catalog No: CFN98734
CAS No: 480-18-2
Price: $30/20mg
4-Hydroxybenzaldehyde

Catalog No: CFN99013
CAS No: 123-08-0
Price: $30/20mg
Scopolamine hydrobromide

Catalog No: CFN99709
CAS No: 114-49-8
Price: $30/20mg
1-Dehydro-10-gingerdione

Catalog No: CFN92374
CAS No: 136826-50-1
Price: $ / mg
Nodakenin

Catalog No: CFN90232
CAS No: 495-31-8
Price: $70/20mg
p-Hydroxy-cinnamic acid

Catalog No: CFN98179
CAS No: 7400-08-0
Price: $70/20mg
Tags: buy Magnolioside | Magnolioside supplier | purchase Magnolioside | Magnolioside cost | Magnolioside manufacturer | order Magnolioside | Magnolioside distributor