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Mannioside A
Mannioside A
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Mannioside A
Price:
CAS No.: 1038922-95-0
Catalog No.: CFN99055
Molecular Formula: C39H62O13
Molecular Weight: 738.9 g/mol
Purity: >=98%
Type of Compound: Steroids
Physical Desc.: Powder
Source: The herbs of Dracaena mannii
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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  • Yale University (USA)
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Mannioside A has anti-inflammatory activity, inhibits carrageenan-induced paw edema in the rat.
Targets: Immunology & Inflammation related
In vivo:
Arch Pharm Res. 2008 May;31(5):653-8.
In vivo anti-inflammatory effect of a new steroidal saponin, mannioside A, and its derivatives isolated from Dracaena mannii.[Pubmed: 18481024]

METHODS AND RESULTS:
A new steroidal saponin, Mannioside A (1), was isolated from the stem bark of Dracaena mannii, together with the known pennogenin (2), pennogenin-3-O-beta-D-glucopyranoside (3) and pennogenin-3-O-alpha-L-rhamnopyranosyl-(1-->2)-[alpha-L-rhamnopyranosyl-(1-->3)]-beta-D-glucopyranoside (4). Their structures were determined using 1D-and 2D-NMR spectroscopy and mass spectrometry.
CONCLUSIONS:
Compounds 1 and 3 significantly inhibited carrageenan-induced paw edema in the rat; compound 4 was moderately active whereas 2 showed very weak activity.
Mannioside A Description
Source: The herbs of Dracaena mannii
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.3534 mL 6.7668 mL 13.5336 mL 27.0673 mL 33.8341 mL
5 mM 0.2707 mL 1.3534 mL 2.7067 mL 5.4135 mL 6.7668 mL
10 mM 0.1353 mL 0.6767 mL 1.3534 mL 2.7067 mL 3.3834 mL
50 mM 0.0271 mL 0.1353 mL 0.2707 mL 0.5413 mL 0.6767 mL
100 mM 0.0135 mL 0.0677 mL 0.1353 mL 0.2707 mL 0.3383 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
CFN90701Polyphyllin H81917-50-2871.0C44H70O17
CFN90869Pennogenin 3-O-beta-chacotrioside55916-52-4885.1C45H72O17
CFN93052Deltonin55659-75-1885.05C45H72O17
CFN90637Cixiophiopogon A288143-27-1887.02C44H70O18
CFN90700Polyphyllin B50773-42-71015.18C51H82O20
CFN90832Zingiberen newsaponin91653-50-81047.2C51H82O22
CFN97162Chonglou Saponin VII68124-04-91031.2 C51H82O21
CFN90821Terrestrosin D179464-23-41049.2C50H80O23
CFN70451Tribulosin79974-46-21151.3C55H90O25
CFN92831Digitonin11024-24-11229.3C56H92O29
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