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Methyl nonyl ketone
Methyl nonyl ketone
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Methyl nonyl ketone
Price: $30 / 20mg
CAS No.: 112-12-9
Catalog No.: CFN70028
Molecular Formula: C11H22O
Molecular Weight: 170.2 g/mol
Purity: >=98%
Type of Compound: Miscellaneous
Physical Desc.: Oil
Source: The volatile oil from Houttuynia cordata
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison
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Size /Price /Stock 10 mM * 1 mL in DMSO / $7.0 / In-stock
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Methyl nonyl ketone could as in-soil odour repellent, it has the potential to repel common voles in the field.
In vivo:
Journal of Chinese Medicinal Materials, 2007, 30(12):1558-1560.
Tissue distribution on methyl nonyl ketone of the volatile oil from Houttyunia cordata in mice.[Pubmed: 18422191]
To study the tissue distribution on Methyl nonyl ketone of the volatile oil from Houttuynia cordata in mice in order to provide a guidance for the clinical trial.
METHODS AND RESULTS:
The concentrations of the volatile oil from Houttuynia cordata in biological samples were determined by GC method.Results:After a single oral dose of 5.0 g/kg volatile oil from Houttuynia cordata in mice, parent drug was mainly distributed in windpipe,intesting,liver,kidney,heart, blood,spleen,lung,brain,muscle;after 7 hours,parent drug of every tissue decreased over 90%.
CONCLUSIONS:
Parent drug mianly distributes in windpipe,intestine,liver,kidney.The experiment provides pharmacokinetic evidence for the rational administration and the further development of Houttuynia cordata.
Methyl nonyl ketone Description
Source: The volatile oil from Houttuynia cordata
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.8754 mL 29.3772 mL 58.7544 mL 117.5088 mL 146.886 mL
5 mM 1.1751 mL 5.8754 mL 11.7509 mL 23.5018 mL 29.3772 mL
10 mM 0.5875 mL 2.9377 mL 5.8754 mL 11.7509 mL 14.6886 mL
50 mM 0.1175 mL 0.5875 mL 1.1751 mL 2.3502 mL 2.9377 mL
100 mM 0.0588 mL 0.2938 mL 0.5875 mL 1.1751 mL 1.4689 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Animal Research:
Pest Management ence, 2013 Mar;69(3):431-6.
Efficacy of methyl nonyl ketone as an in-soil repellent for common voles (Microtus arvalis).[Pubmed: 23292923]
Common voles (Microtus arvalis) can cause enormous damage in agriculture. Tests were conducted using an alternative approach to rodenticide-based vole management by developing an in-soil odour repellent based on the secondary plant metabolite Methyl nonyl ketone (MNK).
METHODS AND RESULTS:
Replicated 25 m(2) plots were established in forage grassland to test efficacy and application schemes using a foam application that included MNK. MNK significantly reduced the number of reopened burrow entrances in all field trials compared with untreated control plots, with repeated application for 6 days reducing vole activity by up to 90%. The addition of black pepper oil (BPO) did not enhance the efficacy of the MNK foam. Voles tended to avoid burrows where MNK was applied and rather opened new burrows instead of reopening the treated burrow entrances. The foam application scheme led to a repellent effect that lasted for about 4-5 days. A single additional application of MNK after 4 days can extend the treatment effects for a further 2 days.
CONCLUSIONS:
The results indicate that MNK has the potential to repel common voles in the field. However, more studies are needed to enhance the duration of a one-off treatment effect to yield a user-friendly field application to manage vole populations.
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