Norsanguinarine | CAS:522-30-5 | Manufacturer ChemFaces

Norsanguinarine

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Description:

Norsanguinarine has antifungal activity, it exhibits 100 % inhibition of A. brassicicola and C. maculans at 1000 ppm whereas. It shows significant cytotoxic activities (ED (50) values < 4 microg/ml) against P-388, KB16, A549, and HT-29 cell lines.

Targets:

Antifection

In vitro:

Folia Microbiol., 2009, 54(3):204-6.

Antifungal activity of the alkaloids from Eschscholtzia californica[Pubmed: 19649736 ]

METHODS AND RESULTS:
The isoquinoline alkaloids hunnemanine and Norsanguinarine have been isolated from methanolic extract of the whole plant of Eschscholzia californica. These two alkaloids were checked for their antifungal activity against phytopathogenic fungi Alternaria melongenae, A. brassicola, A. brassicae, Curvularia lunata, C. maculans, Helminthosporium pennisetti, H. oryzae, H. turcicum, Fusarium undum and F. lini.
CONCLUSIONS:
Hunnemanine exhibited 100 % inhibition of spore germination of A. brassicae, H. pennisetti and F. lini at 1000 ppm whereas Norsanguinarine exhibited 100 % inhibition of A. brassicicola and C. maculans at this concentration.

Norsanguinarine Description

Source:	The herbs of Chelidonium majus
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Norsanguinarine
Price:
CAS No.:	522-30-5
Catalog No.:	CFN92811
Molecular Formula:	C₁₉H₁₁NO₄
Molecular Weight:	317.1 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The herbs of Chelidonium majus
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Cytotoxic Compound Library Antifungal Compound Library Alkaloids Compound Library Antifection Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.1536 mL	15.7679 mL	31.5358 mL	63.0716 mL	78.8395 mL
5 mM	0.6307 mL	3.1536 mL	6.3072 mL	12.6143 mL	15.7679 mL
10 mM	0.3154 mL	1.5768 mL	3.1536 mL	6.3072 mL	7.8839 mL
50 mM	0.0631 mL	0.3154 mL	0.6307 mL	1.2614 mL	1.5768 mL
100 mM	0.0315 mL	0.1577 mL	0.3154 mL	0.6307 mL	0.7884 mL

CFN98259	Sanguinarine	2447-54-3	332.3	C₂₀H₁₄NO₄
CFN92810	Dihydrosanguinarine	3606-45-9	333.1	C₂₀H₁₅NO₄
CFN89299	6-Methoxydihydrosanguinarine	72401-54-8	363.36	C₂₁H₁₇NO₅
CFN89308	6-Ethoxydihydrosanguinarine	28342-31-6	377.39	C₂₂H₁₉NO₅
CFN91469	Angoline	21080-31-9	379.4	C₂₂H₂₁NO₅
CFN91468	6-Ethoxydihydrochelerythrine	7441-89-0	393.4	C₂₃H₂₃NO₅
CFN92811	Norsanguinarine	522-30-5	317.1	C₁₉H₁₁NO₄
CFN91002	Oxysanguinarine	548-30-1	347.3	C₂₀H₁₃NO₅
CFN98449	Chelerythrine	34316-15-9	348.4	C₂₁H₁₈NO₄
CFN95373	Bocconoline	32906-88-0	379.4	C₂₂H₂₁NO₅