ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
3. Inhibitors
Citing Use of our Products
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Tel: (0086)-27-84237683
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock |
10 mM * 1 mL in DMSO / Inquiry |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
J Microbiol Immunol Infect....2021...APMIS.2019, 127(10):688-695Acta Edulis Fungi2020, 27(02):63-76.Phytomedicine Plus2022, 2(1):100207.J Chromatogr B Analyt Technol Bio...2017...Natural Product Communications...2021...Int Immunopharmacol.2022, 106:108603.Plant J.2017, 90(3):535-546
Korean Journal of Medicinal Crop ...2018...Oncol Rep.2021, 46(1):143.J Ginseng Res.2020, 44(4):611-618.Front Nutr.2021, 8: 687851.Eur J Neurosci.2021, 53(11):3548-3560.J Med Food.2016, 19(12):1155-1165Horticulturae2021, 7(1),5.Int. Conference on Med. Sci. and ...2017...
Int J Mol Sci.2020, 21(19):7209.Br J Pharmacol.2018, 175(6):902-923Industrial Crops and Products...2021...Int J Mol Sci.2021, 22(12):6466.J Food Sci Technol.2022, 59(1):212-219.Phytomedicine.2016, 23(4):331-9Universidade Estadual Paulista...2017...
More...
Our products had been exported to the following research institutions and universities, And still growing.
University of Otago (New Zealand)University of Toulouse (France)University of Perugia (Italy)VIT University (India)
Shanghai Institute of Biochemis... (China)Kamphaengphet Rajabhat University (Thailand)Martin Luther University of Hal... (Germany)Leibniz-Institut für Pflanzenb... (Germany)
Universiti Sains Malaysia (Malaysia)University of Eastern Finland (Finland)University of Parma (Italy)
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Phellamurin
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Metabolites.2020, 11(1):E11.Eur J Pharmacol.2018, 832:96-103Appl. Sci. 2021, 11(8),3437.Korean Journal of Pharmacognosy2018, 49(1):76-83Molecules.2019, 24(17):E3127LWT2021, 150:112021.HIV Med.2021, 22(8):690-704.Phytomedicine.2018, 40:37-47Internoational J of Toxicology2020, 10.1177.Evid Based Complement Alternat Med.2017, 2017:1401279
Related Screening Libraries
Description: |
Phellamurin inhibits intestinal P-glycoprotein in a dose-dependent manner, there is a serious interaction occurred between Phellamurin with cyclosporin, to ensure the efficacy of cyclosporin, we suggest that the coadministration of Phellamurin or Phellodendron wilsonii with cyclosporin should be avoided. |
Targets: |
P-gp |
In vivo: |
Planta Med. 2002 Feb;68(2):138-41. | Marked decrease of cyclosporin absorption caused by phellamurin in rats.[Pubmed: 11859464] | Phellamurin is a flavonoid glycoside that is abundant in the leaves of Phellodendron wilsonii Hayata et Kanehira (Rutaceae). In vitro everted rat intestine study indicated that Phellamurin inhibited intestinal P-glycoprotein in a dose-dependent manner. METHODS AND RESULTS: In order to investigate the effect of Phellamurin on cyclosporin absorption and disposition, rats were given cyclosporin (5 mg/kg) with or without Phellamurin in a parallel design. Fluorescence polarization immunoassay was used to determine the blood concentration of cyclosporin. Unanticipatedly, our results indicated that the coadministration of Phellamurin significantly decreased the Cmax of cyclosporin by 77 % and reduced the AUC(0-infinity) of cyclosporin by 56 %.
CONCLUSIONS:
This indicated that a serious interaction occurred between Phellamurin with cyclosporin. To ensure the efficacy of cyclosporin, we suggest that the coadministration of Phellamurin or Phellodendron wilsonii with cyclosporin should be avoided. |
|
Phellamurin Description
Source: |
The barks of Phellodendron chinense Schneid. |
Solvent: |
DMSO, Pyridine, Methanol, Ethanol, etc. |
Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
1 mM |
1.9286 mL |
9.6432 mL |
19.2864 mL |
38.5728 mL |
48.216 mL |
5 mM |
0.3857 mL |
1.9286 mL |
3.8573 mL |
7.7146 mL |
9.6432 mL |
10 mM |
0.1929 mL |
0.9643 mL |
1.9286 mL |
3.8573 mL |
4.8216 mL |
50 mM |
0.0386 mL |
0.1929 mL |
0.3857 mL |
0.7715 mL |
0.9643 mL |
100 mM |
0.0193 mL |
0.0964 mL |
0.1929 mL |
0.3857 mL |
0.4822 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.