ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
Citing Use of our Products
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Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $7.0 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Oncology Letters2018, 4690-4696Food Res Int.2021, 148:110607.Korean Journal of Medicinal Crop ...2018...LWT2020, 130:109535Plants (Basel).2021, 10(12):2795.Oncotarget.2016, 8(51):88386-88400Int J Mol Sci.2021, 22(8):4211.J Med Food.2021, 24(3):209-217.
Chem Biol Interact.2019, 298:1-7Neuropharmacology.2018, 131:68-82J Sci Food Agric.2017, 97(5):1656-1662Phytomedicine.2015, 22(4):498-503Nat Commun.2021, 12(1):681.Mol Neurobiol.2022, 02873-9.J Applied Biological Chemistry...2021...Proc Natl Acad Sci USA....2016...
Front Pharmacol.2021, 12:744624.Chemistry of Plant Materials....2016...Nutrients.2017, 10(1)Front Endocrinol (Lausanne)....2020...Journal of Physiology & Pathology...2018...Asian Pac J Cancer Prev. ...2020...Nutrients.2018, 11(1):E17
Our products had been exported to the following research institutions and universities, And still growing.
Universitas Airlangga (Indonesia)Massachusetts General Hospital (USA)University of Hertfordshire (United Kingdom)Michigan State University (USA)
Tohoku University (Japan)Medical University of Gdansk (Poland)Periyar University (India)Uniwersytet Medyczny w ?odzi (Poland)
University of East Anglia (United Kingdom)Universidade Católica Portuguesa (Portugal)Universiti Sains Malaysia (Malaysia)
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1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Oncotarget.2017, 8(64):108006-108019Food Quality and Safety2018, 2:213-219Front. Physiol.2022, 790345.Clin Exp Pharmacol Physiol.2015, 42(11):1189-97Planta Med.2019, 85(4):347-355AMB Express2020. 10(1):126.Plants (Basel).2020, 9(11):1422.Antioxidants (Basel).2021, 10(11):1831. The Journal of Supercritical Fluids2021, 176:105305.Proc Natl Acad Sci USA.2016, 113(30):E4407-1
Related Screening Libraries
|| Phloretic acid may have antifungal activity. |
|Food Microbiol. 2015 May;47:36-44. |
|Application of Lactobacillus amylovorus DSM19280 in gluten-free sourdough bread to improve the microbial shelf life.[Pubmed: 25583336 ]|
METHODS AND RESULTS:
The present study investigated the antifungal activity of Lactobacillus amylovorus DSM19280 as a starter culture for gluten-free quinoa sourdough bread under pilot-plant conditions to extend the microbial shelf life. Challenge tests against environmental moulds were conducted and a negative control with non-antifungal strain, L. amylovorus DSM20531(T), as well as a chemically acidified and a non-acidified control were included. Organic acid production, antifungal metabolites, carbohydrates changes during fermentation and bread quality were compared to wheat counterparts. The application of quinoa sourdough fermented with the antifungal L. amylovorus DSM19280 extended the mould free shelf life by 4 days compared to the non-acidified control. No significant difference in lactic acid production was found between the lactobacilli strains. HPLC-UV/DAD was used to quantify antifungal compounds. The concentration of 4-hydroxyphenyllactic acid, Phloretic acid, 3-phenyllactic acid and hydroferulic acid were significantly higher (P < 0.01) in the quinoa sourdough fermented with the antifungal L. amylovorus DSM19280 when compared to the non-antifungal strain, thus indicating their contribution to the antifungal activity. Evaluation of bread characteristics such as specific volume or crumb hardness, revealed that the addition of L. amylovorus fermented sourdough also improved bread quality.
In conclusion, the combination of quinoa flour fermented with the antifungal L. amylovorus DSM19280 serves a great potential biopreservative ingredient to produce gluten-free breads with an improved nutritional value, better bread quality and higher safety due to an extended shelf life, and therefore meeting consumer needs for good quality and preservatives-free food products.
|Anticancer Res. 2014 Nov;34(11):6573-9. |
|Cytotoxic and anti-metastatic activities of phenolic compounds from Dendrobium ellipsophyllum.[Pubmed: 25368260]|
Phenolic compounds isolated from Dendrobium ellipsophyllum Tang & Wang (Orchidaceae) have been shown to possess potential pharmacological activity; however, their anticancer as well as anti-metastasis activities are largely unknown. The aim of the present study was to isolate active compounds from D. ellipsophyllum and to explore the possible effects of phenolic compounds isolated from the plant for cytotoxic as well as anti-metastatic properties.
METHODS AND RESULTS:
The compounds were isolated by using chromatographic techniques including silica gel and Sephadex LH20. Each of the isolates was evaluated for their cytotoxicity on H292 human lung cancer cell lines by 2,3-Bis(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide assay. The cytotoxic compounds were further evaluated for apoptosis-inducing and anoikis-sensitizing effects.
Ten phenolic compounds were isolated, 5,7-dihydroxy-chromen-4-one (1:); 4,5-dihydroxy-2,3-dimethoxy-9,10-dihydrophenanthrene (2:); moscatilin (3:), 4,4'-dihydroxy-3,5-dimethoxybibenzyl (4:); 4,5,4'-trihydroxy-3,3'-dimethoxybibenzyl (5:); (2S)-homoeriodictyol (6:); (2S)-eriodictyol (7:); chrysoeriol (8:); Phloretic acid (9:); and luteolin (10:). Compounds 4:, 5:, 8: and 10: exhibited appreciable cytotoxic activity with 50% inhibitory concentration values less than 250 μM. These compounds also showed potential apoptosis induction and anoikis-sensitizing effect at non-toxic concentrations.
Compounds 4:, 5:, 8: and 10: are responsible for cytotoxic and anti-metastatic activities of D. ellipsophyllum.
Phloretic acid Description
||The resin of Boswellia carterii Birdw.
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.