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Physalin X
Physalin X
Information
CAS No. 72497-31-5 Price $318 / 5mg
Catalog No.CFN95329Purity> 95%
Molecular Weight526.5Type of CompoundSteroids
FormulaC28H30O10Physical DescriptionPowder
Download COA    MSDSSimilar structuralComparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $365.7 / In-stock
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    Physalin X

    Physalin X
    Product Name Physalin X
    CAS No.: 72497-31-5
    Catalog No.: CFN95329
    Molecular Formula: C28H30O10
    Molecular Weight: 526.5 g/mol
    Purity: > 95%
    Type of Compound: Steroids
    Physical Desc.: Powder
    Source: The herbs of Physalis alkekengi
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price: $318 / 5mg
    Download: COA    MSDS
    Similar structural: Comparison (Web)  (SDF)
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    product package
  • Plants (Basel).2022, 11(16):2126.
  • Molecules.2016, 21(6)
  • Evidence-based Compl.&Alternative Med.2023, 5417813
  • The Journal of Agromedicine and Medical Sciences2018, 4(1)
  • Ann Transl Med.2019, 7(23):731
  • Antioxidants (Basel).2020, 9(4):326.
  • Journal of Chromatography A2020, 460942
  • Russian J Bioorganic Chemistry 2021, 47:1411-1417.
  • J AOAC Int.2021, 104(6):1634-1651.
  • Industrial Crops and Products2022, 188:115596.
  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
    Biological Activity
    Description: Physalin X exhibited inhibitory activities on NO production with IC50 values of 68.50μM.
    In vitro:
    Org Biomol Chem . 2017 Oct 25;15(41):8700-8704
    Unprecedented 22,26-seco physalins from Physalis angulata and their anti-inflammatory potential[Pubmed: 28991309]
    Two novel physalins, including a 22,26-seco physalin, Physalin X (1), and a 11,15-cyclo-9(10),14(17),22(26)-triseco physalin with an unprecedented aromatic ring, aromaphysalin B (2), were isolated from Physalis angulata L. Their structures were determined by IR, UV, HRESIMS, and 2D NMR spectra as well as theoretical calculations. Compounds 1 and 2 exhibited inhibitory activities on NO production with IC50 values of 68.50 and 29.69 μM, respectively. A plausible biosynthetic pathway for 2 is also discussed.
    Physalin X Description
    Source: The herbs of Physalis alkekengi
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.8993 mL 9.4967 mL 18.9934 mL 37.9867 mL 47.4834 mL
    5 mM 0.3799 mL 1.8993 mL 3.7987 mL 7.5973 mL 9.4967 mL
    10 mM 0.1899 mL 0.9497 mL 1.8993 mL 3.7987 mL 4.7483 mL
    50 mM 0.038 mL 0.1899 mL 0.3799 mL 0.7597 mL 0.9497 mL
    100 mM 0.019 mL 0.095 mL 0.1899 mL 0.3799 mL 0.4748 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Org Biomol Chem. 2017 Oct 25;15(41):8700-8704.
    Unprecedented 22,26-seco physalins from Physalis angulata and their anti-inflammatory potential[Pubmed: 28991309]
    Two novel physalins, including a 22,26-seco physalin, Physalin X (1), and a 11,15-cyclo-9(10),14(17),22(26)-triseco physalin with an unprecedented aromatic ring, aromaphysalin B (2), were isolated from Physalis angulata L. Their structures were determined by IR, UV, HRESIMS, and 2D NMR spectra as well as theoretical calculations. Compounds 1 and 2 exhibited inhibitory activities on NO production with IC50 values of 68.50 and 29.69 μM, respectively. A plausible biosynthetic pathway for 2 is also discussed.
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