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1. Reference standards
2. Pharmacological research
3. Inhibitors
Physalin X
Citing Use of our Products
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / $365.7 / In-stock |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
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Physalin X
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manager@chemfaces.com
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Plants (Basel).2022, 11(16):2126.Molecules.2016, 21(6)Evidence-based Compl.&Alternative Med.2023, 5417813The Journal of Agromedicine and Medical Sciences2018, 4(1)Ann Transl Med.2019, 7(23):731Antioxidants (Basel).2020, 9(4):326. Journal of Chromatography A2020, 460942Russian J Bioorganic Chemistry 2021, 47:1411-1417.J AOAC Int.2021, 104(6):1634-1651.Industrial Crops and Products2022, 188:115596.
Related Screening Libraries
| Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
|
Related Libraries |
|
| Description: |
Physalin X exhibited inhibitory activities on NO production with IC50 values of 68.50μM.
|
| In vitro: |
| Org Biomol Chem . 2017 Oct 25;15(41):8700-8704 | | Unprecedented 22,26-seco physalins from Physalis angulata and their anti-inflammatory potential[Pubmed: 28991309] | | Two novel physalins, including a 22,26-seco physalin, Physalin X (1), and a 11,15-cyclo-9(10),14(17),22(26)-triseco physalin with an unprecedented aromatic ring, aromaphysalin B (2), were isolated from Physalis angulata L. Their structures were determined by IR, UV, HRESIMS, and 2D NMR spectra as well as theoretical calculations. Compounds 1 and 2 exhibited inhibitory activities on NO production with IC50 values of 68.50 and 29.69 μM, respectively. A plausible biosynthetic pathway for 2 is also discussed. |
|
Physalin X Description
| Source: |
The herbs of Physalis alkekengi |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
1.8993 mL |
9.4967 mL |
18.9934 mL |
37.9867 mL |
47.4834 mL |
| 5 mM |
0.3799 mL |
1.8993 mL |
3.7987 mL |
7.5973 mL |
9.4967 mL |
| 10 mM |
0.1899 mL |
0.9497 mL |
1.8993 mL |
3.7987 mL |
4.7483 mL |
| 50 mM |
0.038 mL |
0.1899 mL |
0.3799 mL |
0.7597 mL |
0.9497 mL |
| 100 mM |
0.019 mL |
0.095 mL |
0.1899 mL |
0.3799 mL |
0.4748 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
| Structure Identification: |
| Org Biomol Chem. 2017 Oct 25;15(41):8700-8704. | | Unprecedented 22,26-seco physalins from Physalis angulata and their anti-inflammatory potential[Pubmed: 28991309] | | Two novel physalins, including a 22,26-seco physalin, Physalin X (1), and a 11,15-cyclo-9(10),14(17),22(26)-triseco physalin with an unprecedented aromatic ring, aromaphysalin B (2), were isolated from Physalis angulata L. Their structures were determined by IR, UV, HRESIMS, and 2D NMR spectra as well as theoretical calculations. Compounds 1 and 2 exhibited inhibitory activities on NO production with IC50 values of 68.50 and 29.69 μM, respectively. A plausible biosynthetic pathway for 2 is also discussed. |
|
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