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Beta-Dimorphecolic acid (9(S)-HODE)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $222.6 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Nutrients2020, 12(3):811.Biochem Biophys Res Commun....2018...J Mass Spectrom.2022, 57(2):e4810.Phytomedicine.2017, 24:77-86Journal of Molecular Liquids...2021...Food Chem.2020, 327:126992.Evid Based Complement Alternat Me...2019...J. of Med. Plant Research.2013, 90-151
Semyung University2017, 149407Food Chem.2021, 377:131976. Integr Med Res.2017, 6(4):395-403Biol Pharm Bull.2020, 43(10):1534-1541.J Cell Mol Med.2018, 22(9):4236-4242Applied Biological Chemistry ...2022...J Appl Microbiol.2022, 132(2):949-963.J Agric Food Chem....2021...
Biomed Pharmacother.2021, 139:111585. Int J Mol Sci.2019, 20(8):E1855Front Cell Dev Biol.2021, 9:588093.J Agric Food Chem....2021...Universidade Estadual Paulista...2017...Molecules.2020, 25(20):4851.Molecules2020, 25(4):892
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Centrum Menselijke Erfelijkheid (Belgium)Instituto de Investigaciones Ag... (Chile)Uniwersytet Gdański (Poland)
Beta-Dimorphecolic acid (9(S)-HODE)
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1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Molecules.2020, 25(11):2599. Molecules.2018, 23(9):E2121J Pharm Pharmacol.2022, rgac033. J Ethnopharmacol.2016, 194:219-227Toxicol In Vitro.2018, 52:94-105Nat Prod Commun.2018, 10.1177Phytother Res.2018, 32(5):923-932Industrial Crops and Products2022, 186:115298Nutrients.2021, 13(12):4364.J Hematol Oncol.2018, 11(1):112
Related Screening Libraries
|Pharmacogn Mag . Jul-Sep 2015;11(43):477-85 |
|A direct protein kinase B-targeted anti-inflammatory activity of cordycepin from artificially cultured fruit body of Cordyceps militaris[Pubmed: 26246722]|
|Background: Cordyceps militaris is one of well-known medicinal mushrooms with anti-inflammatory, anti-cancer, anti-diabetic, and anti-obesity activities.
Objective: The objective of the following study is to isolate chemical components from the ethanol extract (Cm-EE) from Cordyceps militaris and to evaluate their anti-inflammatory activities.
Materials and methods: Column chromatographic separation was performed and anti-inflammatory roles of these compounds were also examined by using NO production and protein kinase B (AKT) activity assays.
Results: From Cm-EE, 13 constituents, including trehalose (1), cordycepin (2), 6-hydroxyethyladenosine (3), nicotinic amide (4), butyric acid (5), β-dimorphecolic acid (6), α-dimorphecolic acid (7), palmitic acid (8), linoleic acid (9), cordycepeptide A (10), 4-(2-hydroxy-3-((9E,12E)-octadeca-9,12-dienoyloxy)propoxy)-2-(trimethylammonio)butanoate (11), 4-(2-hydroxy-3-(palmitoyloxy)propoxy)-2-(trimethylammonio)butanoate (12), and linoleic acid methyl ester (13) were isolated. Of these components, compound 2 displayed a significant inhibitory effect on NO production in lipopolysaccharide (LPS)-activated RAW264.7 cells. Furthermore, this compound strongly and directly suppressed the kinase activity of AKT, an essential signalling enzyme in LPS-induced NO production, by interacting with its ATP binding site.
Conclusion: C. militaris could have anti-inflammatory activity mediated by cordycepin-induced suppression of AKT.|
Beta-Dimorphecolic acid (9(S)-HODE) Description
||The herbs of Piper cubeba
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|ChemInform 63(32):7624-7633 |
|Enantioselective syntheses of (-)-pinellic acid, α- and β-dimorphecolic acid[Reference: WebLink]|
|An efficient enantioselective convergent approach for the synthesis of (−)-pinellic acid 1, α- and β-dimorphecolic acid (2 and 3) from 1,9-nonane diol is described. The synthetic strategy features Sharpless asymmetric hydroxylation, Sonogashira coupling and Birch reduction.|