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Phytin
Phytin
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Phytin
Price: $30 / 20mg
CAS No.: 3615-82-5
Catalog No.: CFN99795
Molecular Formula: C6H6Ca6O24P6
Molecular Weight: 888.42 g/mol
Purity: >=98%
Type of Compound: Miscellaneous
Physical Desc.: Powder
Source: The herbs of Oryza sativa
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: 1. Phytin and magnesium citrate have hypocalciuric effect , they can reduce urinary calcium excretion in rats fed on high-calcium diets.
2. A six-day treatment with phytin can restore the normal level of the liver monooxygenase system components and MMW peptides, also can reduce the level of lactic acid (LA) and increased that of pyruvic acid (PA) in liver tissues, which lead to a sharp drop in the LA/MA ratio indicative of a decrease in the extent of hypoxia.
3. Individually phytin, EDTA and copper (Cu2+) have inhibitory effect on growth of Gram positive as well as Gram negative bacteria, phytin preferentially protects only Gram negative bacteria from Cu 2+ ion toxicity,phytin also has chelating ability.
Targets: Calcium Channel | Antifection
Phytin Description
Source: The herbs of Oryza sativa
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.1256 mL 5.628 mL 11.2559 mL 22.5119 mL 28.1398 mL
5 mM 0.2251 mL 1.1256 mL 2.2512 mL 4.5024 mL 5.628 mL
10 mM 0.1126 mL 0.5628 mL 1.1256 mL 2.2512 mL 2.814 mL
50 mM 0.0225 mL 0.1126 mL 0.2251 mL 0.4502 mL 0.5628 mL
100 mM 0.0113 mL 0.0563 mL 0.1126 mL 0.2251 mL 0.2814 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Phytin References Information
Citation [1]

World J. Urol., 1994;12(6):323-8.

Effects of magnesium citrate and phytin on reducing urinary calcium excretion in rats.[Pubmed: 7881470]
he aim of this study was to determine and compare the effects of both magnesium citrate and Phytin on reducing urinary calcium excretion under high-calcium-diet conditions during single and combined treatments. An animal experiment was carried out over a period of 4 weeks in 35 male rats. Urinary calcium excretion was reduced significantly by magnesium citrate and/or Phytin in rats fed on high-calcium diets. The hypocalciuric effect of magnesium citrate was more evident than that of Phytin. Urinary magnesium excretion was high in all experimental groups. However, the urinary magnesium/calcium ratios showed a consistent increase only in the groups treated with magnesium citrate. Urinary citrate excretion showed a relative increase with the introduction of magnesium citrate plus Phytin; however, in both the high-calcium-diet group and the magnesium-citrate group this was found to be reduced. Urinary phosphate excretion was slightly higher in the groups treated with Phytin. There was no definite difference in urinary oxalate concentration between the groups. No significant change was noted in the serum concentration of calcium, magnesium, or phosphate.
Citation [2]

Eksp. Klin. Farmakol., 2001,64(1):71-3.

[Effect of benzonal on the absorptive-secretory function in the liver of immature rabbits in post-compression period of long-term compression syndrome].[Pubmed: 11558444]
The absorptive-secretory function of hepatocytes using chromodiagnostic test by means of cardiogrin in rabbits at the age of 1 month in postcompression period of prolonged compression syndrome (PCS) was studied. It was established that the given function of hepatocytes was sufficiently and stably depressed for PCS. By effect of inductor of hepatocytes' monooxygenase system benzonal the disorders in parameters of cardiogreen pharmacokinetics are being distinctly removed. The velocity of blood stream in the liver was restored up to a level in health animals. It is supposed that an inclusion of benzonal into a complex of therapeutical remedies allows to enhance an effectiveness in PCS treatment during prepubescent period.
Citation [3]

Indian J. Exp. Biol., 1999, 37(6):618-20.

Protection by phytin against Cu~(2+) ion toxicity in few bacteria[Reference: WebLink]
ndividually Phytin, EDTA and copper (Cu~(2+)) have inhibitory effect on growth of Gram positive as well as Gram negative bacteria. Cu~(2+) has been found to be more toxic to Rhizobium of the four species of bacteria studied. Toxicity of Cu~(2+) is reduced by EDTA. Differential effect of Phytin has been observed between Gram positive and Gram negative bacteria, Phytin preferentially protects only Gram negative bacteria from Cu~(2+) ion toxicity. This has been interpreted that strong electrostatic repulsion between anionic Phytin and anionic biopolymer teichoic acid on the surface of Gram positive bacteria results in inhibition of penetration of Phytin into them. Thus the chelating ability of Phytin, an anionic biomolecule present in many foodstuff, has some beneficial effect too.
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