ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
How to Order
Orders via your E-mail:
1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
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Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
Delivery & Payment method
1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
2. We accept: Wire transfer & Credit card & Paypal & Western Union
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $203.8 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
J Biol Chem.2014, 289(3):1723-31Mol Cells.2015, 38(9):765-72Proc Natl Acad Sci USA....2016...Nat Plants.2016, 3:16205US20170000760 A12016, 42740Evid Based Complement Alternat Me...2017...Neurochem Int.2018, 121:114-124Yakugaku Zasshi.2018, 138(4):571-579
J Sep Sci.2018, 41(9):1938-1946Chemistry of Natural Compounds...2018...Wageningen University & Research...2018...J of Health Science and Alternati...2019...Nutr Res Pract2019, 13:e45J Pharm Biomed Anal.2019, 164:119-127J Ethnopharmacol.2019, 241:112025Food Chem.2019, 276:768-775
Oxid Med Cell Longev2019, 9056845:13Nutrients2020, 12(2):488Biomedicine & Pharmacotherapy...2020...Agronomy2020, 10(10),1489Int J Mol Med.2020, 45(5):1514-1524.Biochem Biophys Res Commun....2020...Eur J Pharmacol.2020, 889:173589.
Our products had been exported to the following research institutions and universities, And still growing.
St. Jude Children Research Hosp... (USA)National Chung Hsing University (Taiwan)Universite Libre de Bruxelles (Belgium)Cancer Research Initatives Foun... (Malaysia)
Subang Jaya Medical Centre (Malaysia)Nicolaus Copernicus Uniwersity (Poland)University of Zurich (Switzerland)University of Amsterdam (Netherlands)
Johannes Gutenberg University M... (Germany)Rio de Janeiro State University (Brazil)Research Unit Molecular Epigene... (Germany)
Inquire / Order:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Front Immunol.2018, 9:2655Int. J. of Pha. and Phy. Res.2015, 7(1):144-149Journal of Apicultural Research2021, 60(1)Mol Cell.2017, 68(4):673-685Phytomedicine.2018, 40:37-47Metabolites.2020, 10(12):497.Nutrients.2018, 10(12)Br J Pharmacol.2018, 175(6):902-923LWT-Food Science and Technology2017, 75:488-496Appl. Sci.2020, 10(16),5482.
Related Screening Libraries
||1,3,6-Tri-O-galloylglucose shows anti-inflammatory activity. |
||Immunology & Inflammation related|
|Chinese Pharmaceutical Journal, 2015,50(19):1673-7. |
|Study on the anti-inflammatory active constituents of Mangifera indica L. seed kernel.[Reference: WebLink]|
To study the anti-inflammatory active constituents of Mangifera indica L. seed kernel. |
METHODS AND RESULTS:
The compounds were isolated by silica gel column chromatography, Sephadex LH-20 column chromatography and ODS column chromatography.Their structures were elucidated by spectral analyses and physicochemical properties. The anti-inflammatory activities of selected isolated compounds were evaluated as inhibitory activities against lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW264.7 cell lines by Griess reaction. Eight compounds were obtained from n-butanol fraction oi Mangifera indica L. seed kernel, whose structures were elucidated as 4-O-ethylgallic acid (1), gallic acid (2), citric acid(3), 1,2,3,4,6-penta-O-galloylglucose(4),1,3,6-Tri-O-galloylglucose(5), hyperoside(6), quercetin-3-O-rhamnopyranoside(7), and mangiferin(8). Compounds 1, 2 and 4-8 exhibited potent inhibitory effect on NO production in LPS-induced macrophages, especially compounds 6 and 8 showed the best inhibitory activity with IC50 values of 16.5 and 19.5 μmol·L-1, respectively.
Compounds 1 and 3-8 were obtained from Mangifera indica L.seed kernel for the first time.Compounds 1, 2 and 4-8 are the anti-inflammatory active constituents oi Mangifera indica L.seed kernel.Compounds 6 and 8 are the most potent anti-inflammatory active constituents.
||The peels of Punica granatum L.
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.