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    Natural Products
    Pimentol
    Pimentol
    Information
    CAS No. 141913-95-3 Price
    Catalog No.CFN90573Purity>=98%
    Molecular Weight494.5Type of CompoundPhenylpropanoids
    FormulaC23H26O12Physical DescriptionPowder
    Download     COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
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    Pimentol

    Pimentol
    Product Name Pimentol
    CAS No.: 141913-95-3
    Catalog No.: CFN90573
    Molecular Formula: C23H26O12
    Molecular Weight: 494.5 g/mol
    Purity: >=98%
    Type of Compound: Phenylpropanoids
    Physical Desc.: Powder
    Source: The herbs of Pimenta dioica
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Price:
    Inquire / Order: manager@chemfaces.com
    Technical Inquiries: service@chemfaces.com
    Tel: +86-27-84237783
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    1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Phenylpropanoids Compound Library
  • Biological Activity
    Description: Pimentol shows antioxidative activity.
    In vitro:
    Bioscience Biotechnology and Biochemistry, 1997, 61(2):263-266.
    Spice Constituents Scavenging Free Radicals and Inhibiting Pentosidine Formation in a Model System.[Reference: WebLink]
    Many antioxidants have been found in spices and herbs, and some of them are well known as strong scavengers of active oxygen radicals. We have isolated active products, which markedly inhibited the formation of malondialdehyde (MDA) from 2-deoxyribose and the hydroxylation of benzoate with the hydroxyl radical, from methanol extracts of allspice and clove.
    METHODS AND RESULTS:
    Pimentol from allspice, and biflorin and its isomer, abbreviated as clove3, from clove were identified as the active principles. These revealed strong activity as hydroxyl radical scavengers at a concentration of 2.0 μμ. The antioxidative activities in an in vitro model system involving the rabbit erythrocyte membrane ghost were as strong as those of α-tocopherol at 200 μm. Such advanced glycation end products (AGE) as pentosidine are biomarkers of diabetes mellitus, and active oxygens have been suggested to be involved in the formation of AGE.
    CONCLUSIONS:
    The above-mentioned free radical scavengers effectively inhibited the formation of pentosidine in a model system of Nα-t-butoxycarbonyl-fructoselysine and Nα-t-butoxycarbonyl-arginine.
    Journal of Natural Products, 2000, 63(6):749-752.
    Galloylglucosides from berries of Pimenta dioica.[Reference: WebLink]

    METHODS AND RESULTS:
    Three new galloylglucosides, (4S)-alpha-terpineol 8-O-beta-D-(6-O-galloyl)glucopyranoside (1); (4R)-alpha-terpineol 8-O-beta-D-(6-O-galloyl)glucopyranoside (2), and 3-(4-hydroxy-3-methoxyphenyl)propane-1,2-diol 2-O-beta-D-(6-O-galloyl)glucopyranoside (3), were isolated from the berries of Pimenta dioica together with three known compounds, gallic acid (4), Pimentol (5), and eugenol 4-O-beta-D-(6-O-galloyl)glucopyranoside (6). The structures of 1-3 were elucidated on the basis of MS and NMR spectral data and enzymatic hydrolysis.
    CONCLUSIONS:
    These galloylglucosides (1-3, 5, and 6) showed radical-scavenging activity nearly equivalent to that of gallic acid (4) against 1,1-diphenyl-2-picrylhydrazyl radical.
    Pimentol Description
    Source: The herbs of Pimenta dioica
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.0222 mL 10.1112 mL 20.2224 mL 40.4449 mL 50.5561 mL
    5 mM 0.4044 mL 2.0222 mL 4.0445 mL 8.089 mL 10.1112 mL
    10 mM 0.2022 mL 1.0111 mL 2.0222 mL 4.0445 mL 5.0556 mL
    50 mM 0.0404 mL 0.2022 mL 0.4044 mL 0.8089 mL 1.0111 mL
    100 mM 0.0202 mL 0.1011 mL 0.2022 mL 0.4044 mL 0.5056 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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