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    Natural Products
    Quercetin-3-gentiobioside
    Information
    CAS No. 7431-83-6 Price $298 / 10mg
    Catalog No.CFN93585Purity>=98%
    Molecular Weight626.5Type of CompoundFlavonoids
    FormulaC27H30O17Physical DescriptionYellow powder
    Download     COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $235.4 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    Quercetin-3-gentiobioside

    Quercetin-3-gentiobioside
    Product Name Quercetin-3-gentiobioside
    CAS No.: 7431-83-6
    Catalog No.: CFN93585
    Molecular Formula: C27H30O17
    Molecular Weight: 626.5 g/mol
    Purity: >=98%
    Type of Compound: Flavonoids
    Physical Desc.: Yellow powder
    Source: The herbs of Solanum nigrum L.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Price: $298 / 10mg
    Inquire / Order: manager@chemfaces.com
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  • J Biochem Mol Toxicol.2017, 31(9)
  • Molecules.2018, 23(7):E1659
  • Pak J Pharm Sci.2019, 32(6):2879-2885
  • Int J Med Sci.2020, 17(5):626-631
  • University of Limpopo2016, 1777
  • J of App. Res. on Med&Aromatic Plants2020, 100291.
  • BMC Complement Altern Med.2018, 18(1):303
  • J Nat Med.2020, 74(1):65-75
  • Food Chem.2019, 278:683-691
  • Phytother Res.2019, 10.1002
  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Flavonoids Compound Library
  • Biological Activity
    Description: Quercetin-3-gentiobioside may show significant inhibitor on AR and AGEs formation activities.
    In vitro:
    Biomed Res Int. 2017;2017:7375615.
    Inhibitory Effect of Chemical Constituents Isolated from Artemisia iwayomogi on Polyol Pathway and Simultaneous Quantification of Major Bioactive Compounds.[Pubmed: 28512639 ]
    Blocking the polyol pathway plays an important role preventing diabetic complications. Therefore, aldose reductase (AR) and advanced glycation endproducts (AGEs) formation has significant effect on diabetic complications. Artemisia iwayomogi has long been used as treatment of various diseases in Korea. However, no literatures have reported on AR and AGEs formation inhibitory activities of A. iwayomogi.
    METHODS AND RESULTS:
    For these reasons, we aimed to assess that A. iwayomogi had potential as anti-diabetic complications agents. We led to isolation of two coumarins (1 and 2), nine flavonoids (3-11), five caffeoylquinic acids (12-16), three diterpene glycosides (17-19), and one phenolic compound (20) from A. iwayomogi. Among them, hispidulin (4), 6-methoxytricin (6), arteanoflavone (7), Quercetin-3-gentiobioside (10), 1,3-di-O-caffeoylquinic acid (13), and suavioside A (18) were first reported on the isolation from A. iwayomogi. Not only two coumarins (1 and 2), nine flavonoids (3-11), and five caffeoylquinic acids (12-16) but also extracts showed significant inhibitor on AR and AGEs formation activities. We analyzed contents of major bioactive compounds in Korea's various regions of A. iwayomogi.
    CONCLUSIONS:
    Overall, we selected Yangyang, Gangwon-do, from June, which contained the highest amounts of bioactive compounds, as suitable areas for cultivating A. iwayomogi as preventive or therapeutic agent in the treatment of diabetic complications.
    Quercetin-3-gentiobioside Description
    Source: The herbs of Solanum nigrum L.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.5962 mL 7.9808 mL 15.9617 mL 31.9234 mL 39.9042 mL
    5 mM 0.3192 mL 1.5962 mL 3.1923 mL 6.3847 mL 7.9808 mL
    10 mM 0.1596 mL 0.7981 mL 1.5962 mL 3.1923 mL 3.9904 mL
    50 mM 0.0319 mL 0.1596 mL 0.3192 mL 0.6385 mL 0.7981 mL
    100 mM 0.016 mL 0.0798 mL 0.1596 mL 0.3192 mL 0.399 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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