| Structure Identification: |
| Zhongguo Zhong Yao Za Zhi . 2021 Mar;46(5):1160-1167 | | Research on chemical constituents from Artemisia annua[Pubmed: 33787111] | | Chemical constituents were isolated and purified from the water extract of Artemisia annua by column chromatography of HP-20 macroporous resin, silica gel, ODS, Sephadex LH-20, HW-40, and semi-preparative RP-HPLC. Their structures were elucidated by physicochemical properties and spectral analyses. As a result, Fifteen compounds were isolated and identified as vitexnegheteroin M(1), sibricose A5(2), Securoside A(3), citrusin D(4), annphenone(5), E-melilotoside(6), esculetin(7), scopoletin-7-O-β-D-glucoside(8), eleutheroside B_1(9), chrysosplenol D(10), patuletin-3-O-β-D-glucopyranoside(11), quercetin-7-O-β-D-glucoside(12), rutin(13), apigenin 6,8-di-C-β-D-glucopyranoside(14), isoschaftoside(15), among them, compounds 1-4 were identified from Artemisia for the first time. Additionally, the isolates were evaluated for their inhibitory effects on the production of PGE_2 in LPS-simulated RAW264.7 macrophages. The results showed that compounds 1, 2, 8, and 10-15 could reduce PGE_2 levels, to a certain extent. | | Chemical Journal of Chinese Universities, 01 Jan 2003, 24(1):61-63 | | New Sucrose Esters from Securidaca Inappendiculata[Reference: WebLink] | | Three sucrose esters, #beta#-D-(3,4-O-disinapoyl)fructofuranosyl-#alpha#-D-(6-O-sinapoyl)gluco-pyranoside(1), #beta#--D-(3-O-feruloyl)fructofuranosyl-#alpha#-D-(6-O-sinapoyl)glucopyrano-side(2), and #beta#-D-(3-O-feruloyl) fructofuranosyl-#alpha#-D-(6-O-feruloyl)glucopyranoside(3) were isolated from the stems of Securidaca inappendiculata collected from Yunnan Province. Among them, compound 3 was a new sucrose ester and was named as Securoside A . All structures were elucidated on the basis of chemical and spectroscopic evidence, especially ~(13)C, ~(1)M NMR and ESI-MS experiments. |
|
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)