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Rauvovertine C
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Rauvovertine C
Price:
CAS No.: 2055073-74-8
Catalog No.: CFN89450
Molecular Formula: C20H23N3O
Molecular Weight: 321.41 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The stems of Rauvolfia verticillata.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Rauvovertine C shows cytotoxicity in vitro against human tumor cell lines.
Rauvovertine C Description
Source: The stems of Rauvolfia verticillata.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.1113 mL 15.5565 mL 31.1129 mL 62.2258 mL 77.7823 mL
5 mM 0.6223 mL 3.1113 mL 6.2226 mL 12.4452 mL 15.5565 mL
10 mM 0.3111 mL 1.5556 mL 3.1113 mL 6.2226 mL 7.7782 mL
50 mM 0.0622 mL 0.3111 mL 0.6223 mL 1.2445 mL 1.5556 mL
100 mM 0.0311 mL 0.1556 mL 0.3111 mL 0.6223 mL 0.7778 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Fitoterapia. 2015 Dec;107:44-48.
Hexacyclic monoterpenoid indole alkaloids from Rauvolfia verticillata.[Pubmed: 26474672 ]

METHODS AND RESULTS:
Five new hexacyclic monoterpenoid indole alkaloids, rauvovertine A (1), 17-epi-rauvovertine A (2), Rauvovertine B (3), 17-epi-Rauvovertine B (4), and Rauvovertine C (5) together with 17 known analogues were isolated from the stems of Rauvolfia verticillata. Compounds 1/2 and 3/4 were obtained as C-17 epimeric mixtures due to rapid hemiacetal tautomerism in solution.
CONCLUSIONS:
The structures of 1-5 were established by spectroscopic analysis and with the aid of molecular modeling. The new alkaloids were evaluated for their cytotoxicity in vitro against human tumor HL-60, SMMC-7721, A-549, MCF-7, and SW-480 cell lines.
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Ginkgolide B

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(+)-Taxifolin

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CAS No: 17654-26-1
Price: $70/20mg
Cannabidivarin

Catalog No: CFN89253
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Price: $ / mg
Eburicol

Catalog No: CFN97175
CAS No: 6890-88-6
Price: $ /
Magnoflorine

Catalog No: CFN98071
CAS No: 2141-09-5
Price: $98/20mg
Calceolarioside A

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Isomangiferin

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Price: $238/20mg
L-Phenylalanine

Catalog No: CFN93152
CAS No: 63-91-2
Price: $30/20mg
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