Rosmarinyl glucoside | CAS:910028-78-3

Rosmarinyl glucoside

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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $475.0 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Description:

Anti-inflammatory effects of rosmarinic acid-4-O-β-D-glucoside in reducing acute lung injury in mice infected with influenza virus.
The scientists found a solution to make Rosmarinic acid available for skin care products. They used glycosylation to convert Rosmarinic acid into Rosmarinyl Glucoside, which is bioavailable, water-soluble and stable in formulations. After penetration trough skin barriers Rosmarinyl Glucoside disintegrates back into Rosmarinic acid. Its biologically active in cells with anti-ageing properties - protecting collagen and hyaluronic acid from destruction by inhibiting enzymes (collagen-destroying enzyme and hyaluronidase). Protects against the degradation of the cellular matrix and captures free-radicals.
A healing herb and one of the most well-known polyphenols for skincare, Rosmarinyl Glucoside guards skin’s extracellular matrix to maintain collagen and keep skin firm, strong and resilient. Its antioxidant activity captures the free radicals that damage skin and inhibit the breakdown of the hyaluronic acid that keeps skin hydrated, plumped, and refreshed.

Rosmarinyl glucoside Description

Source:	The herbs of Rosmarinus officinalis L.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

Animal Research:

Antiviral Res . 2017 Aug;144:34-43.

Anti-inflammatory effects of rosmarinic acid-4-O-β-D-glucoside in reducing acute lung injury in mice infected with influenza virus[Pubmed: 28461072]

Rosmarinic acid-4-O-β-D-glucoside (RAG) is a dicaffeoyl phenolic compound isolated from Sarcandra glabra (Thunb.) Nakai. Preliminary studies show that RAG has significant anti-inflammatory properties and can alleviate ear swelling in mice and the paw swelling in rats. Here, the anti-influenza effects of RAG were investigated in mice infected with A/FM/1/47 H1N1 virus. The survival rate and body weight were observed, the lung edema, virus copies, inflammatory cytokines (including IL-4, IL-5, TNF-α and IFN-γ) and oxidative damage indexes (including SOD, MDA, NO, and CAT) were measured. Moreover, immune cell recruitment in alveoli was measured with white blood cells and differential counts. Therapeutic RAG concentrations substantially improve the symptoms, mitigate body weight loss and alleviate lung edema induced by virus, thus improve survival protection effects. Furthermore, RAG was shown to regulate influenza virus-induced inflammatory cytokine expression, specifically by downregulating the Th1 cell cytokines IFN-γ, TNF-α and upregulating the Th2 cell cytokines IL-4, IL-5. Cell migration and infiltration were also diminished after RAG administration.

CAS No.	910028-78-3	Price	$413 / 5mg
Catalog No.	CFN95297	Purity	>=98%
Molecular Weight	522.5	Type of Compound	Phenols
Formula	C₂₄H₂₆O₁₃	Physical Description	Oil
Download	COA MSDS	Similar structural	Comparison (Web) (SDF)

Product Name	Rosmarinyl glucoside
CAS No.:	910028-78-3
Catalog No.:	CFN95297
Molecular Formula:	C₂₄H₂₆O₁₃
Molecular Weight:	522.5 g/mol
Purity:	>=98%
Type of Compound:	Phenols
Physical Desc.:	Oil
Source:	The herbs of Rosmarinus officinalis L.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Price:	$413 / 5mg
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Anti-inflammatory Compound Library Antioxidants Compound Library Phenols Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.9139 mL	9.5694 mL	19.1388 mL	38.2775 mL	47.8469 mL
5 mM	0.3828 mL	1.9139 mL	3.8278 mL	7.6555 mL	9.5694 mL
10 mM	0.1914 mL	0.9569 mL	1.9139 mL	3.8278 mL	4.7847 mL
50 mM	0.0383 mL	0.1914 mL	0.3828 mL	0.7656 mL	0.9569 mL
100 mM	0.0191 mL	0.0957 mL	0.1914 mL	0.3828 mL	0.4785 mL

CFN98546	Lithospermic acid	28831-65-4	538.46	C₂₇H₂₂O₁₂
CFN91005	Monomethyl lithospermate	933054-33-2	552.5	C₂₈H₂₄O₁₂
CFN91004	Salvianolic acid Y	1638738-76-7	718.6	C₃₆H₃₀O₁₆
CFN99332	Salvianolic acid B	115939-25-8	718.62	C₃₆H₃₀O₁₆
CFN90390	Magnesium Lithospermate B	122021-74-3	740.90	C₃₆H₂₈MgO₁₆
CFN90691	9'-Methyl lithospermate B	1167424-31-8	732.64	C₃₇H₃₂O₁₆
CFN90810	9'''-Methyl salvianolate B	1167424-32-9	732.7	C₃₇H₃₂O₁₆
CFN90690	Dimethyl lithospermate B	875313-64-7	746.67	C₃₈H₃₄O₁₆
CFN80272	Salvianolic acid E	142998-46-7	718.15	C₃₆H₃₀O₁₆
CFN95614	Schizotenuin A	144608-09-3	716.6	C₃₆H₂₈O₁₆