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    Natural Products
    Saprirearine
    Saprirearine
    Information
    CAS No. 453518-30-4 Price
    Catalog No.CFN96073Purity>=98%
    Molecular Weight296.4Type of CompoundDiterpenoids
    FormulaC20H24O2Physical DescriptionOil
    Download     COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    Saprirearine

    Saprirearine
    Product Name Saprirearine
    CAS No.: 453518-30-4
    Catalog No.: CFN96073
    Molecular Formula: C20H24O2
    Molecular Weight: 296.4 g/mol
    Purity: >=98%
    Type of Compound: Diterpenoids
    Physical Desc.: Oil
    Source: The herbs of Salvia prionitis
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price:
    Inquire / Order: manager@chemfaces.com
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Diterpenoids Compound Library
  • Biological Activity
    Description: Standard reference
    In vitro:
    J Nat Prod. 2002 Jul;65(7):1016-20.
    Bioactive abietane and seco-abietane diterpenoids from Salvia prionitis.[Pubmed: 12141863]

    METHODS AND RESULTS:
    From the roots of Salvia prionitis a new tricyclic diterpene, Saprirearine (1), a new anhydride-type compound, saprionide (2), a new 7,8-seco-abietane diterpene derivative, 7,8-seco-para-ferruginone (3), and two new 4,5-seco-5,10-friedo-abietane diterpenoids, 4-hydroxysaprorthoquinone (4) and 3-keto-4-hydroxysaprorthoquinone (5), were isolated. Their structures were established by spectroscopic methods and chemical transformation.
    CONCLUSIONS:
    Compound 3 showed antimicrobial activities against two Gram-positive organisms, Staphylococcus aureus and Micrococcus luteus, with MIC values of 20.0 and 15.0 microM, respectively. Compound 4 showed significant inhibition against topoisomerase Iota with an IC50 value of 0.8 microM. Compound 5 exhibited cytotoxic activities against HL-60 human leukemia and the SGC-7901 and MKN-28 stomach cancer cell lines, with IC50 values of 4.6, 0.2, and 0.3 microM, respectively.
    Saprirearine Description
    Source: The herbs of Salvia prionitis
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.3738 mL 16.8691 mL 33.7382 mL 67.4764 mL 84.3455 mL
    5 mM 0.6748 mL 3.3738 mL 6.7476 mL 13.4953 mL 16.8691 mL
    10 mM 0.3374 mL 1.6869 mL 3.3738 mL 6.7476 mL 8.4345 mL
    50 mM 0.0675 mL 0.3374 mL 0.6748 mL 1.3495 mL 1.6869 mL
    100 mM 0.0337 mL 0.1687 mL 0.3374 mL 0.6748 mL 0.8435 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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