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Sculponeatin O
Sculponeatin O
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Product Name Sculponeatin O
Price:
CAS No.: 1169806-00-1
Catalog No.: CFN99268
Molecular Formula: C28H40O4
Molecular Weight: 440.6 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Cryst.
Source: The herbs of Rabdosia amethystoides
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Sculponeatin O may have protective effects on the lipid peroxidation-damaged live cells.
Sculponeatin O Description
Source: The herbs of Rabdosia amethystoides
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.2696 mL 11.3482 mL 22.6963 mL 45.3926 mL 56.7408 mL
5 mM 0.4539 mL 2.2696 mL 4.5393 mL 9.0785 mL 11.3482 mL
10 mM 0.227 mL 1.1348 mL 2.2696 mL 4.5393 mL 5.6741 mL
50 mM 0.0454 mL 0.227 mL 0.4539 mL 0.9079 mL 1.1348 mL
100 mM 0.0227 mL 0.1135 mL 0.227 mL 0.4539 mL 0.5674 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chem Pharm Bull (Tokyo). 2009 May;57(5):525-7.
New terpenoids from Isodon sculponeata.[Pubmed: 19420789]

METHODS AND RESULTS:
Two new ent-kaurane diterpene derivatives, Sculponeatin N (1) and Sculponeatin O (2), and a new A-ring contracted oleanane triterpenoid, sculponeatic acid (5), were isolated from the plant Isodon sculponeata. Their structures were elucidated on the basis of extensive spectroscopic analysis.
CONCLUSIONS:
This is the first report of natural occurrence of an A-ring contracted oleanane triterpenoid.
CFN99268Sculponeatin O1169806-00-1440.6 C28H40O4
CFN96482ent-17-Hydroxykaura-9(11),15-dien-19-oic acid1588516-88-4316.44C20H28O3
CFN97752ent-17-Hydroxykaur-15-en-19-oic acid35030-38-7318.46C20H30O3
CFN97033ent-Kauran-17,19-dioic acid60761-79-7334.5 C20H30O4
CFN96674Siegeskaurolic acid52645-97-3320.47C20H32O3
CFN98424ent-16beta,17-Dihydroxy-19-kauranoic acid3301-61-9336.5 C20H32O4
CFN95172ent-16beta,17-dihydroxy-9(11)-kauren-19-oic acid55483-24-4334.5C20H30O4
CFN97973Pterisolic acid F1401419-90-6366.5C20H30O6
CFN89189Neotripterifordin149249-32-1318.45C20H30O3
CFN99398ent-kaurane-3,16,17-triol130855-22-0322.5 C20H34O3
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