ChemFaces is a professional high-purity natural products manufacturer.
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2. Pharmacological research
3. Inhibitors
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / Inquiry |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
Eur J Pharmacol.2018, 832:96-103Cell Mol Biol(Noisy-le-grand)...2019...Front Pharmacol.2020, 11:683.Biomolecules2021, 11(10),1513.Internoational J of Toxicology...2020...Separation Science Plus...2022...Int Immunopharmacol....2021...Evid Based Complement Alternat Me...2021...
Pharmaceutics.2022, 14(12):2765.J Chromatogr B Analyt Technol Bio...2021...Int J Mol Sci.2018, 19(9):E2825J Nat Med.2022, 76(1):59-67. J Insect Sci.2020, 20(5):18. Microb Biotechnol....2021...Molecules2022, 27(9):2992.Molecules.2019, 24(22):E4022
Analytical methods2019, 11(6)Phytother Res.2018, 32(5):923-932Food Chem.2021, 360:130063.Food Quality and Safety2018, 2:213-219Food and Fermentation Industries...2018...Oncotarget.2017, 8(53):90925-90947Cells.2023, 12(1):168.
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Our products had been exported to the following research institutions and universities, And still growing.
Institute of Bioorganic Chemist... (Poland)University of Medicine and Phar... (Romania)University of Minnesota (USA)National Chung Hsing University (Taiwan)
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Soyacerebroside II
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
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Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Journal of Functional Foods2022, 98:105271.Int Immunopharmacol.2019, 71:361-371Phytother Res.2022, 10.1002:ptr.7602.Food Sci Nutr.2019, 8(1):246-256Natural Product Communications2022, 7(3):1-7.Molecules.2022, 27(22):7887.J of Health Science and Alternative Medicine2019, 1(1)Sci Rep.2021, 11(1):21038.Neurotoxicology.2022, 91:218-227.J Cachexia Sarcopenia Muscle.2022, 13(6):3149-3162.
Related Screening Libraries
| Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
|
Related Libraries |
|
| Description: |
Soyacerebroside II exhibits ionophoretic activity for Ca2+ ion. Soyacerebrosides I and II have modulating the cellular immune response effects, they show obvious inhibitory activity on IL-18 secretion in human peripheral blood mononuclear cells (PBMC). |
| Targets: |
IL Receptor | Calcium Channel |
| In vitro: |
| Chem Pharm Bull (Tokyo). 1990 Nov;38(11):2933-8. | | Sphingolipids and glycerolipids. I. Chemical structures and ionophoretic activities of soya-cerebrosides I and II from soybean.[Pubmed: 2085876] |
METHODS AND RESULTS:
Two glycosphingolipids named soya-cerebrosides I and II were isolated from soybean, the seeds of Glycine max Merrill (Leguminosae), and their chemical structures have been elucidated on the basis of physicochemical evidence and several chemical degradation reactions.
CONCLUSIONS:
By using a newly constructed liquid membrane-type apparatus (W-08) for measurement of ion-transport and ion-binding activities and by employing a method using human erythrocyte membranes for measurement of ion-permeability, it has been found that Soyacerebroside II exhibits ionophoretic activity for Ca2+ ion. | | Lipids. 2009 Aug;44(8):759-63. | | An isomeric mixture of novel cerebrosides isolated from Impatiens pritzellii reduces lipopolysaccharide-induced release of IL-18 from human peripheral blood mononuclear cells.[Pubmed: 19609788] | An isomeric mixture of two cerebrosides, soyacerebroside I and Soyacerebroside II, was isolated from an ethno drug, the rhizomes of Impatiens pritzellii Hook. f. var. hupehensis Hook. f., and their structures were identified by spectroscopic (NMR, MS) analysis.
METHODS AND RESULTS:
In order to determine the immunomodulatory activities of soya-cerebrosides I and II, the effects of the mixture of cerebrosides (MC) on cytotoxicity of human peripheral blood mononuclear cells (PBMC) and the inhibitory activities to lipopolysaccharide (LPS)-induced interleukin (IL)-18 in PBMC were studied. The MC at concentrations of 10 and 1 microM, without toxicity to PBMC in 24 h, showed obvious inhibitory activity on IL-18 secretion.
CONCLUSIONS:
Because of this effect of modulating the cellular immune response, soya-cerebrosides I and II were considered to be the active substances of this ethno drug. |
|
Soyacerebroside II Description
| Source: |
The fruits of Glycine max |
| Solvent: |
DMSO, Pyridine, Methanol, Ethanol, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
1.4006 mL |
7.0028 mL |
14.0056 mL |
28.0112 mL |
35.014 mL |
| 5 mM |
0.2801 mL |
1.4006 mL |
2.8011 mL |
5.6022 mL |
7.0028 mL |
| 10 mM |
0.1401 mL |
0.7003 mL |
1.4006 mL |
2.8011 mL |
3.5014 mL |
| 50 mM |
0.028 mL |
0.1401 mL |
0.2801 mL |
0.5602 mL |
0.7003 mL |
| 100 mM |
0.014 mL |
0.07 mL |
0.1401 mL |
0.2801 mL |
0.3501 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
| Structure Identification: |
| Zhongguo Zhong Yao Za Zhi. 2014 Jan;39(2):258-61. | | Chemical constituents from leaves of Ilex latifolia.[Pubmed: 24761642] |
METHODS AND RESULTS:
Nine compounds were isolated from the leaves of Ilex latifolia. Their structures were respectively identified as 5-hydroxy-6, 7, 8, 4'-tetramethoxyflavone (1), tangeretin (2), nobiletin (3), 5-hydroxy-6, 7, 8, 3', 4'-pentamethoxyflavone (4), 5, 6, 7, 8, 4'-pentamethoxyflavonol (5), 5, 6, 7, 8, 3', 4'-hexamethoxy-flavonol (6), 5-hydroxy-3', 4', 7-trimethoxyflavanone (7), soyacerebroside I (8), and Soyacerebroside II (9) by their physicochemical properties and spectroscopic data.
CONCLUSIONS:
Compounds 1-9 were isolated from this plant for the first time. |
|
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