Natural Products
- ChemFaces is a professional high-purity natural products manufacturer.
- Product Intended Use
- 1. Reference standards
- 2. Pharmacological research
- 3. Inhibitors
| Size /Price /Stock | 10 mM * 1 mL in DMSO / Inquiry |
| Other Packaging | *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
| Size /Price /Stock | 10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock |
| Related Libraries |
| Description: | Taurocholic acid feeding shows cytoprotective effects on the biliary tree after adrenergic denervation of the liver; taurocholic acid feeding prevents tumor necrosis factor-alpha-induced damage of cholangiocytes by a PI3K-mediated pathway. Rectal administration of taurocholic acid can stimulate glucagon-like peptide-1 and peptide YY by TGR5 receptor activation, which may have potential for the management of type 2 diabetes and obesity. | ||||||
| Targets: | TNF-α | PI3K | Akt | p38MAPK | Caspase | TGR5 | ||||||
| In vivo: |
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| Source: | From snake bile. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: | Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com |
| After receiving: | The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.9391 mL | 9.6956 mL | 19.3911 mL | 38.7822 mL | 48.4778 mL |
| 5 mM | 0.3878 mL | 1.9391 mL | 3.8782 mL | 7.7564 mL | 9.6956 mL |
| 10 mM | 0.1939 mL | 0.9696 mL | 1.9391 mL | 3.8782 mL | 4.8478 mL |
| 50 mM | 0.0388 mL | 0.1939 mL | 0.3878 mL | 0.7756 mL | 0.9696 mL |
| 100 mM | 0.0194 mL | 0.097 mL | 0.1939 mL | 0.3878 mL | 0.4848 mL |
| Kinase Assay: |
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| Animal Research: |
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