ChemFaces is a professional high-purity natural products manufacturer.
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $295.7 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Molecules.2020, 25(20):4851.Journal of Ginseng Research...2019...Biomed Pharmacother.2022, 145:112474. J Cell Physiol.2020, 10.1002Am J Chin Med.2016, 44(8):1719-1735Curr Eye Res.2018, 43(1):27-34Biomed Pharmacother.2019, 116:108987J Separation Science & Technology...2016...
Plant Direct.2021, 5(12):e372. J Ethnopharmacol.2020, 269:113752. Antioxidants (Basel)....2021...ACS Nano.2018, 12(4):3385-3396Appl. Sci.2020, 10(20), 7323.Planta Med.2019, 85(3):217-224Food Chem.2019, 274:345-350Biomedicines.2021, 9(8):996.
J of Food Quality2020, 8851285.Cell Death Dis.2019, 10(12):882Int J Immunopathol Pharmacol....2019...Phytomedicine.2019, 58:152893Oxid Med Cell Longev....2021...J Nat Prod.2015, 78(6):1339-4Advances in Traditional Medicine...2020...
Our products had been exported to the following research institutions and universities, And still growing.
Johannes Gutenberg University M... (Germany)Aveiro University (Portugal)University of Eastern Finland (Finland)Institute of Pathophysiology Me... (Austria)
Worcester Polytechnic Institute (USA)University of Beira Interior (Portugal)Martin Luther University of Hal... (Germany)Seoul National University of Sc... (Korea)
Heidelberg University (Germany)Fraunhofer-Institut für Moleku... (Germany)Max Rubner-Institut (MRI) (Germany)
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1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Plos One.2019, 15(2):e0220084J Pharm Biomed Anal.2021, 196:113931. Journal of Analytical Chemistry2017, 854-861Nat Plants.2016, 3:16205British Jou. Med.&Med. Research2014, 1802-1811Korean J. Medicinal Crop Sci.2021, 29(6):425-433Sci Rep. 2017, 12953(7)Int J Mol Sci.2021, 22(14):7324.Food Chem.2019, 274:345-350Pharmaceuticals (Basel). 2021, 14(10):986.
Related Screening Libraries
|Size /Price /Stock
||10 mM * 100 uL in DMSO / Inquiry / In-stock |
10 mM * 1 mL in DMSO / Inquiry / In-stock
||Triterpenoids Compound Library
|| Reference standards.|
|Nat Prod Res. 2017 Mar;31(6):691-695. |
|Antimutagenic components in Glycyrrhiza against N-methyl-N-nitrosourea in the Ames assay.[Pubmed: 27466044 ]|
|Antimutagenesis against N-nitroso compounds contribute to prevention of human cancer. We have found that Glycyrrhiza aspera ethanolic extract exhibits antimutagenic activity against N-methyl-N-nitrosourea (MNU) using the Ames assay with Salmonella typhimurium TA1535.|
METHODS AND RESULTS:
In the present study, eight purified components from Glycyrrhiza, namely glabridin, glycyrrhetinic acid, glycyrrhizin, licochalcone A, Licoricesaponin H2 , licoricesaponin G2, liquiritigenin and liquiritin were evaluated for their antimutagenicity against MNU in the Ames assay with S. typhimurium TA1535. Glycyrrhetinic acid, glycyrrhizin, licoricesaponin G2, Licoricesaponin H2 and liquiritin did not show the antimutagenicity against MNU in S. typhimurium TA1535. Glabridin, licochalcone A and liquiritigenin reduced revertant colonies derived from MNU in S. typhimurium TA1535 without showing cytotoxic effects, indicating that these compounds possess antimutagenic activity against MNU.
The inhibitory activity of glabridin and licochalcone A was more effective than that of liquiritigenin.
Thus, Glycyrrhiza contains antimutagenic components against DNA alkylating, direct-acting carcinogens.
Licoricesaponin H2 Description
||The roots of Glycyrrhiza glabra L.
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Biol Pharm Bull. 2005 Jan;28(1):161-4. |
|Phylogenetic relationship of Glycyrrhiza lepidota, American licorice, in genus Glycyrrhiza based on rbcL sequences and chemical constituents.[Pubmed: 15635184 ]|
METHODS AND RESULTS:
Two known saponins, licorice-saponin H2 and macedonoside A, were isolated from the stolons of Glycyrrhiza lepidota (American licorice) as major saponins. Since Licoricesaponin H2 and macedonoside A are minor saponins isolated from the three glycyrrhizin-producing species (i.e. G. glabra, G. uralensis, G. inflata) and the three macedonoside C-producing species (i.e. G. macedonica, G. echinata, G. pallidiflora), respectively, the present study suggests that G. lepidota is an intermediate of both glycyrrhizin-producing and macedonoside C-producing species.
The phylogenetic tree constructed from the nucleotide sequences of ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit gene (rbcL) of these seven Glycyrrhiza plants indicated that G. lepidota was separated from the other six Glycyrrhiza species, and this phylogenetic relationship was in accordance with their saponin compositions.