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    Natural Products
    Citrusin B
    Citrusin B
    Information
    CAS No. 105279-10-5 Price $388 / 5mg
    Catalog No.CFN95178Purity>=98%
    Molecular Weight568.6Type of CompoundLignans
    FormulaC27H36O13Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)  (SDF)
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $446.2 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
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    Citrusin B

    Citrusin B
    Product Name Citrusin B
    CAS No.: 105279-10-5
    Catalog No.: CFN95178
    Molecular Formula: C27H36O13
    Molecular Weight: 568.6 g/mol
    Purity: >=98%
    Type of Compound: Lignans
    Physical Desc.: Powder
    Source: The stems of Sambucus williamsii
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Price: $388 / 5mg
    Inquire / Order: manager@chemfaces.com
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  • Inflammation.2021, doi: 10.1007
  • Biochem Biophys Res Commun.2021, 534:802-807.
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Lignans Compound Library
  • Biological Activity
    Description: Citrusin B exhibits moderate in vitro inhibitory effect on tobacco mosaic virus replication with IC₅₀ values 0.26 mmol L⁻1.
    In vitro:
    Nat Prod Res. 2012;26(15):1375-80.
    A new seco-neolignan glycoside from the root bark of Ailanthus altissima.[Pubmed: 21916771 ]

    METHODS AND RESULTS:
    A new seco-neolignan glycoside, seco-dehydrodiconiferyl alcohol-4-O-β-D-glucopyranoside, together with eight known compounds, were obtained from the EtOH extract of the root bark of Ailanthus altissima. Their structures were elucidated based on the spectroscopic data.
    CONCLUSIONS:
    Three neolignan glycosides including 7,9,9'-trihydroxy-3,3',5'-trimethoxy-8-O-4'-neolignan-4-O-β-D-glucopyranoside, sonchifolignan B and Citrusin B exhibited moderate in vitro inhibitory effect on tobacco mosaic virus replication with IC₅₀ values 0.30, 0.35 and 0.26 mmol L⁻¹, respectively.
    Citrusin B Description
    Source: The stems of Sambucus williamsii
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    IF=36.216(2019)

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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.7587 mL 8.7935 mL 17.5871 mL 35.1741 mL 43.9676 mL
    5 mM 0.3517 mL 1.7587 mL 3.5174 mL 7.0348 mL 8.7935 mL
    10 mM 0.1759 mL 0.8794 mL 1.7587 mL 3.5174 mL 4.3968 mL
    50 mM 0.0352 mL 0.1759 mL 0.3517 mL 0.7035 mL 0.8794 mL
    100 mM 0.0176 mL 0.0879 mL 0.1759 mL 0.3517 mL 0.4397 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Zhongguo Zhong Yao Za Zhi. 2013 Jul;38(13):2118-24.
    A new lignan from stems of Sargentodoxa cuneata.[Pubmed: 24079238]
    Sargentodoxae Caulis was prepared from the stems of Sargentodoxa cuneata.
    METHODS AND RESULTS:
    Twenty compounds from the the stems of S. cuneata collected in Huangshan Mountain, Anhui province, were isolated and purified by column chromatography on macroporous resin (HPD100), silica gel, Sephadex LH-20 and semi-preparative HPLC. Their structures were elucidated on the basis of physico-chemical properties and spectral data analyses as (7R,8S)-3,3 '-5-trimethoxy-4,9-dihydroxy-4',7-expoxy-5',8-lignan-7'-en-9'-oic acid 4-O-beta-D-glucopyranoside(1), 1-O-(vanillic acid) -6-O-vanilloyl-beta-D-glucopyranoside(2), 4-hydroxyphenylethyl-6-O-coumaroyl-beta-D-glucopyranoside(3), Citrusin B(4), cinnamoside(5), (-) -isolariciresinol 4'-O-beta-D-glucopyranoside (6), (-) -isolariciresinol 4-O-beta-D-glucopyranoside (7), 1-O-(vanillic acid) -6-(3", 5"-dimethoxy-galloyl) -beta-D-glucopyranoside (8), 4-hydroxyphenyl-ethyl-6-O-(E) -caffeoyl-beta-D-glucopyranoside (9), (-)-syringaresinol 4'-O-beta-D-glucopyranoside (10), (-)-syringaresinol di-O-beta-D-glucopyranoside (11), aegineoside (12), calceolarioside B (13), 4-hydroxy-3-methoxy-acetophenone-4-O-alpha-L-rhamnopyranosyl-(1 --> 6)-beta-D-glucopyranoside (14), 4-hydroxy-3-methoxy-acetophenone-4-O-beta-D-apiofuranosyl-(1 --> 6) -beta-D-glucopyranoside (15), (-) -epicatechin (16), salidroside (17), 3,4-dihydroxy-phenyl ethyl-beta-D-glucopyranoside (18), chlorogenic acid (19) and protocatechuic acid (20).
    CONCLUSIONS:
    Compound 1 was a new compound and compounds 2-7 were isolated from this plant for the first time.
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