Valechlorine | CAS:51771-49-4 | Manufacturer ChemFaces

Valechlorine

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Valechlorine Description

Source:	The herbs of Valeriana officinalis L.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Molecules, 2015, 20(4):5740-53.

Antileishmanial and cytotoxic compounds from Valeriana wallichii and identification of a novel nepetolactone derivative.[Reference: WebLink]

The chloroform extract of Valeriana wallichii (V. wallichii) rhizomes was investigated to elucidate the structures responsible for reported antileishmanial activity. Besides bornyl caffeate (1, already been reported by us previously), bioassay-guided fractionation resulted in two additional cinnamic acid derivatives 2-3 with moderate leishmanicidal activity.
METHODS AND RESULTS:
The structure of a novel nepetolactone derivative 4 having a cinnamic acid moiety was elucidated by means of spectral analysis. To the best of our knowledge villoside aglycone (5) was isolated from this plant for the first time. The bioassay-guided fractionation yielded two new (compounds 6-7) and two known valtrates (compounds 8-9) with leishmanicidal potential against Leishmania major (L. major) promastigotes. In addition, β-bisabolol (10), α-kessyl alcohol (11), valeranone (12), bornyl isovalerate (13) and linarin-2-O-methylbutyrate (14) were identified.
CONCLUSIONS:
This is the first report on the isolation of 4'-demethylpodophyllotoxin (15), podophyllotoxin (16) and pinoresinol (17) in V. wallichii. In total thirteen known and four new compounds were identified from the extract and their cytotoxic and antileishmanial properties were evaluated.

Product Name	Valechlorine
Price:
CAS No.:	51771-49-4
Catalog No.:	CFN90622
Molecular Formula:	C₂₂H₃₁ClO₈
Molecular Weight:	458.93 g/mol
Purity:	>=98%
Type of Compound:	Iridoids
Physical Desc.:	Oil
Source:	The herbs of Valeriana officinalis L.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Cytotoxic Compound Library Anti-leishmanial Compound Library Iridoids Compound Library Antifection Inhibitor Library

Description:	Valeranone shows antileishmanial and cytotoxic activity.
Targets:	Antifection

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.179 mL	10.8949 mL	21.7898 mL	43.5796 mL	54.4745 mL
5 mM	0.4358 mL	2.179 mL	4.358 mL	8.7159 mL	10.8949 mL
10 mM	0.2179 mL	1.0895 mL	2.179 mL	4.358 mL	5.4475 mL
50 mM	0.0436 mL	0.2179 mL	0.4358 mL	0.8716 mL	1.0895 mL
100 mM	0.0218 mL	0.1089 mL	0.2179 mL	0.4358 mL	0.5447 mL

CFN96824	Chlorovaltrate K	96801-92-2	460.94	C₂₂H₃₃ClO₈
CFN97119	Cerbinal	65597-42-4	204.2	C₁₁H₈O₄
CFN97120	Cerberic acid	65597-44-6	220.2	C₁₁H₈O₅
CFN95668	Jatairidoid A	1393577-29-1	384.4	C₁₉H₂₈O₈
CFN95669	Jatairidoid B	1393577-30-4	384.4	C₁₉H₂₈O₈
CFN95670	Jatamanvaltrate N	1395056-08-2	384.4	C₁₉H₂₈O₈
CFN90205	Valepotriate	18296-44-1	422.47	C₂₂H₃₀O₈
CFN96822	Didrovaltrate	18296-45-2	424.49	C₂₂H₃₂O₈
CFN96823	IVHD-valtrate	28325-56-6	540.60	C₂₇H₄₀O₁₁
CFN96825	Acevaltrate	25161-41-5	480.51	C₂₄H₃₂O₁₀