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    Natural Products
    N-Methylcorydalmine
    N-Methylcorydalmine
    Information
    CAS No. 81010-29-9 Price $398 / 5mg
    Catalog No.CFN95204Purity>95%
    Molecular Weight355.4Type of CompoundAlkaloids
    FormulaC21H25NO4Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)  (SDF)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $338.3 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    N-Methylcorydalmine

    N-Methylcorydalmine
    Product Name N-Methylcorydalmine
    CAS No.: 81010-29-9
    Catalog No.: CFN95204
    Molecular Formula: C21H25NO4
    Molecular Weight: 355.4 g/mol
    Purity: >95%
    Type of Compound: Alkaloids
    Physical Desc.: Powder
    Source: The roots of Stephania elegans
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price: $398 / 5mg
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  • Biomed Pharmacother.2020, 131:110673.
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Alkaloids Compound Library
  • Biological Activity
    Description: N-Methylcorydalmine may exhibit significant anti-hypoxia activity.
    In vitro:
    Zhongguo Zhong Yao Za Zhi. 2019 Feb;44(4):723-729.
    Chemical constituents from rhizome of Menispermum dauricum and their anti-hypoxic activities.[Pubmed: 30989885]

    METHODS AND RESULTS:
    To study the chemical constituents from the rhizome of Menispermum dauricum,fifteen compounds, N-Methylcorydalmine( 1),thalifoline( 2),stepholidine( 3),acutumine( 4),daurisoline( 5),acutumidine( 6),dauricicoline( 7),bianfugecine( 8),6-O-demethylmenisporphine( 9),bianfugedine( 10),dauricoside( 11),eleutheroside D( 12),aristolactone( 13),aristoloterpenateⅠ( 14) and aristolochic acid( 15) were isolated from 75% ethanol extract of Menispermi Rhizoma by using thin layer chromatography and column chromatography methods. Their structures were identified based on their physicochemical properties and spectral data. Among them,compounds 12-15 were obtained from the genus Menispermum for the first time. Six alkaloids with higher contents were subjected to evaluate the anti-hypoxic activities by using MTT method.
    CONCLUSIONS:
    As a result,six alkaloids exhibited significant anti-hypoxia activities.
    N-Methylcorydalmine Description
    Source: The roots of Stephania elegans
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.8137 mL 14.0687 mL 28.1373 mL 56.2746 mL 70.3433 mL
    5 mM 0.5627 mL 2.8137 mL 5.6275 mL 11.2549 mL 14.0687 mL
    10 mM 0.2814 mL 1.4069 mL 2.8137 mL 5.6275 mL 7.0343 mL
    50 mM 0.0563 mL 0.2814 mL 0.5627 mL 1.1255 mL 1.4069 mL
    100 mM 0.0281 mL 0.1407 mL 0.2814 mL 0.5627 mL 0.7034 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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