Science | Nature | Cell | View More
Natural Products
Vincetoxicoside B
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Vincetoxicoside B
Price: $100 / 20mg
CAS No.: 22007-72-3
Catalog No.: CFN90737
Molecular Formula: C21H20O11
Molecular Weight: 448.38 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Source: The herbs of Hypericum japonicum Thunb.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $42.3 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Cancer Research Initatives Foun... (Malaysia)
  • Complutense University of Madrid (Spain)
  • Kamphaengphet Rajabhat University (Thailand)
  • Uniwersytet Medyczny w ?odzi (Poland)
  • Universidad Miguel Hernández (Spain)
  • University of East Anglia (United Kingdom)
  • The Australian National University (Australia)
  • Sanford Burnham Medical Researc... (USA)
  • Almansora University (Egypt)
  • Uniwersytet Jagielloński w Kra... (Poland)
  • Hamdard University (India)
  • More...
Package
Featured Products
Neochamaejasmine A

Catalog No: CFN92151
CAS No: 90411-13-5
Price: $418/5mg
Crocin

Catalog No: CFN90227
CAS No: 42553-65-1
Price: $40/20mg
Trilobatin

Catalog No: CFN98658
CAS No: 4192-90-9
Price: $30/20mg
Oleic acid

Catalog No: CFN94800
CAS No: 112-80-1
Price: $30/20mg
Procyanidin B2

Catalog No: CFN99558
CAS No: 29106-49-8
Price: $138/20mg
1-Dehydro-10-gingerdione

Catalog No: CFN92374
CAS No: 136826-50-1
Price: $ / mg
Canthin-6-one

Catalog No: CFN98730
CAS No: 479-43-6
Price: $318/5mg
Atractylenolide II

Catalog No: CFN99945
CAS No: 73069-14-4
Price: $70/20mg
Ginsenoside Rg1

Catalog No: CFN99967
CAS No: 22427-39-0
Price: $40/20mg
Petunidin-3-O-galactoside chloride

Catalog No: CFN92042
CAS No: 28500-02-9
Price: $318/5mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Vincetoxicoside B , quercetin, kaempferol , and (-)-epicatechin show synergistic antifungal activities with the FICI values <0.5.
Targets: Antifection
In vitro:
J Asian Nat Prod Res. 2017 Jan;19(1):47-52.
Chemical constituents from the rhizome of Polygonum paleaceum and their antifungal activity.[Pubmed: 27309618 ]

METHODS AND RESULTS:
A new compounds neopaleaceolactoside (1), along with nine known compounds phyllocoumarin (2), quercetin (3), quercitrin (4), quercetin-3-methyl ether (5), Vincetoxicoside B (6), isoquercitrin (7), kaempferol (8), (-)-epicatechin (9), and chlorogenic acid (10), was isolated from Polygonum paleaceum Wall. Their chemical structures were established based on one-dimensional and two-dimensional nuclear magnetic resonance techniques, mass spectrometry and by comparison with spectroscopic data reported. Some selected compounds were screened for their antifungal activity. Quercetin (3), Vincetoxicoside B (6), kaempferol (8), and (-)-epicatechin (9) showed synergistic antifungal activities with the FICI values <0.5.
CONCLUSIONS:
A preliminary structure-activity relationship could be observed that free 3-OH in the structure of flavonoids was important for synergistic antifungal activity.
Vincetoxicoside B Description
Source: The herbs of Hypericum japonicum Thunb.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Lappaol B

Catalog No: CFN95242
CAS No: 62359-60-8
Price: $333/10mg
Marginatoxin

Catalog No: CFN95174
CAS No: 1422536-56-8
Price: $318/10mg
Otobaphenol

Catalog No: CFN95476
CAS No: 10240-16-1
Price: $318/10mg
Isoformononetin

Catalog No: CFN95024
CAS No: 486-63-5
Price: $288/5mg
New compound 6

Catalog No: CFN95259
CAS No: N/A
Price: $413/5mg
8'-O-(3-hydroxy-3-methylglutaryl)-...

Catalog No: CFN95308
CAS No: 69790-31-4
Price: $318/5mg
Gardenin D

Catalog No: CFN95133
CAS No: 29202-00-4
Price: $318/5mg
2-O-cinnamoyl-beta-D-glucose

Catalog No: CFN95111
CAS No: N/A
Price: $318/20mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.2303 mL 11.1513 mL 22.3025 mL 44.605 mL 55.7563 mL
5 mM 0.4461 mL 2.2303 mL 4.4605 mL 8.921 mL 11.1513 mL
10 mM 0.223 mL 1.1151 mL 2.2303 mL 4.4605 mL 5.5756 mL
50 mM 0.0446 mL 0.223 mL 0.4461 mL 0.8921 mL 1.1151 mL
100 mM 0.0223 mL 0.1115 mL 0.223 mL 0.4461 mL 0.5576 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
J Pharm Biomed Anal. 2016 Jan 25;118:228-34.
Simultaneous determination and pharmacokinetic study of eight components in rat plasma by UHPLC-MS/MS after oral administration of Hypericum japonicum Thunb extract.[Pubmed: 26580819 ]

METHODS AND RESULTS:
A rapid and sensitive assay based on ultra high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) was established and validated for the simultaneous determination of gallic acid, protocatechuic acid, vanillic acid, caffeic acid, epicatechin, isoquercitrin, Vincetoxicoside B and quercetin in rat plasma using catechin and daidzein as the internal standards (IS). Plasma samples added internal standards were acidified with formic acid then pretreated by direct protein precipitation with acetonitrile. The separation of eight constituents was achieved on a C18 column with gradient elution using methanol and 0.2% acetic acid aqueous solution as the mobile phase and detected by multiple reaction monitoring using electrospray ionization source in the positive-negative ionization mode. The method was validated for sufficient specificity, precision, accuracy, and sensitivity over the concentration range of 10-6000 ng mL(-1) for gallic acid, 1.5-3000 ng mL(-1) for protocatechuic acid, 10-15000 ng mL(-1) for vanillic acid, 2-3600 ng mL(-1) for caffeic acid, 1.5-3600 ng mL(-1) for epicatechin, 4-6000 ng mL(-1) for isoquercitrin, 2-9000 ng mL(-1) for Vincetoxicoside B, and 20-18000 ng mL(-1) for quercetin. The overall intra‑run precision and the inter‑run precision were showed in the range of 1.0-14.2% and 2.8-12.9%, respectively, and the accuracy was no more than 12.8%.
CONCLUSIONS:
This analytical method was successfully applied to investigate the pharmacokinetics of eight ingredients in rats after oral administration of Hypericum japonicum Thunb extract.
Neochamaejasmine A

Catalog No: CFN92151
CAS No: 90411-13-5
Price: $418/5mg
Crocin

Catalog No: CFN90227
CAS No: 42553-65-1
Price: $40/20mg
Trilobatin

Catalog No: CFN98658
CAS No: 4192-90-9
Price: $30/20mg
Oleic acid

Catalog No: CFN94800
CAS No: 112-80-1
Price: $30/20mg
Procyanidin B2

Catalog No: CFN99558
CAS No: 29106-49-8
Price: $138/20mg
1-Dehydro-10-gingerdione

Catalog No: CFN92374
CAS No: 136826-50-1
Price: $ / mg
Canthin-6-one

Catalog No: CFN98730
CAS No: 479-43-6
Price: $318/5mg
Atractylenolide II

Catalog No: CFN99945
CAS No: 73069-14-4
Price: $70/20mg
Ginsenoside Rg1

Catalog No: CFN99967
CAS No: 22427-39-0
Price: $40/20mg
Petunidin-3-O-galactoside chloride

Catalog No: CFN92042
CAS No: 28500-02-9
Price: $318/5mg
Tags: buy Vincetoxicoside B | Vincetoxicoside B supplier | purchase Vincetoxicoside B | Vincetoxicoside B cost | Vincetoxicoside B manufacturer | order Vincetoxicoside B | Vincetoxicoside B distributor