Wilforol A | CAS:167882-66-8 | Manufacturer ChemFaces

Wilforol A

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Wilforol A Description

Source:	The herbs of Tripterygium wilfordii Hook. f.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

J Am Chem Soc. 2015 Sep 23;137(37):11864-7.

Total Synthesis of Celastrol, Development of a Platform to Access Celastroid Natural Products.[Pubmed: 26331410 ]

Celastroid natural products, triterpenes, have been and continue to be investigated in clinical trials.
METHODS AND RESULTS:
Celastrol, and for that matter any member of the celastroid family, was prepared for the first time through chemical synthesis starting from 2,3-dimethylbutadiene. A triene cyclization precursor generated in 12 steps underwent a nonbiomimetic polyene cyclization mediated by ferric chloride to generate the generic celastroid pentacyclic core.
CONCLUSIONS:
In the cyclization, engagement of a tetrasubstituted olefin formed adjacent all carbon quaternary centers stereospecifically. With access to the carbocyclic core of the family of natural products, wilforic acid and Wilforol A were prepared en route to racemic celastrol.

Product Name	Wilforol A
Price:
CAS No.:	167882-66-8
Catalog No.:	CFN92083
Molecular Formula:	C₂₉H₃₈O₅
Molecular Weight:	466.6 g/mol
Purity:	>=98%
Type of Compound:	Triterpenoids
Physical Desc.:	Powder
Source:	The herbs of Tripterygium wilfordii Hook. f.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Triterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.1432 mL	10.7158 mL	21.4316 mL	42.8633 mL	53.5791 mL
5 mM	0.4286 mL	2.1432 mL	4.2863 mL	8.5727 mL	10.7158 mL
10 mM	0.2143 mL	1.0716 mL	2.1432 mL	4.2863 mL	5.3579 mL
50 mM	0.0429 mL	0.2143 mL	0.4286 mL	0.8573 mL	1.0716 mL
100 mM	0.0214 mL	0.1072 mL	0.2143 mL	0.4286 mL	0.5358 mL

CFN91639	Populninic acid	120090-56-4	470.69	C₃₀H₄₆O₄
CFN90169	Pristimerin	1258-84-0	464.64	C₃₀H₄₀O₄
CFN99198	Celastrol	34157-83-0	450.61	C₂₉H₃₈O₄
CFN90136	Demethylzeylasteral	107316-88-1	480.60	C₂₉H₃₆O₆
CFN92084	Zeylasteral	87064-16-2	494.6	C₃₀H₃₈O₆
CFN91915	Zeylasterone	78012-25-6	510.62	C₃₀H₃₈O₇
CFN91916	Blepharotriol	849590-42-7	482.61	C₂₉H₃₈O₆
CFN96477	Triptocalline A	201534-10-3	442.64	C₂₈H₄₂O₄
CFN91918	6-Oxo-23-norpristimerol	118172-79-5	466.61	C₂₉H₃₈O₅
CFN92083	Wilforol A	167882-66-8	466.6	C₂₉H₃₈O₅