ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
3. Inhibitors
Citing Use of our Products
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2. Delivery address
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / Inquiry |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
J Chem Inf Model....2021...Plos One.2020, 10.1371Exp Parasitol.2018, 194:67-78Int Immunopharmacol....2021...J Ethnopharmacol.2022, 289:115018. Molecules.2018, 23(12):E3103J Ethnopharmacol.2019, 241:112025BMC Plant Biol.2020, 20(1):214.
Molecules.2019, 24(11):E2102Analytical Letters 2021, 54(4).Revista Brasileira de Farmacognos...2021...Environ Toxicol.2019, 34(4):513-520.BMC Complement Altern Med....2017...Curr Res Virol Sci.2022, 3:100019.Lab Chip.2018, 18(6):971-978Pharmacol Rep.2018, 70(6):1195-1201
Oncotarget.2015, 6(31):30831-49BMC Complement Altern Med....2017...Sci Rep.2017, 7:40345The Korea Journal of Herbology...2016...Arch Pharm Res.2015, 38(6):1080-9Anal Bioanal Chem....2018...Molecules. 2013, 18(11):14105-21
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Our products had been exported to the following research institutions and universities, And still growing.
University of British Columbia (Canada)Semmelweis Unicersity (Hungary)University of Amsterdam (Netherlands)Charles University in Prague (Czech Republic)
Srinakharinwirot University (Thailand)Chungnam National University (Korea)Monash University (Australia)University of Pretoria (South Africa)
Osmania University (India)University of Sao Paulo (Brazil)S.N.D.T. Women's University (India)
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Wilforol A
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Molecules.2016, 21(6)Malaysian J of Fundamental and Applied Sciences 2018, 14(3):368-373Molecules.2021, 26(18):5665.Ind Crops Prod.2015, 67:185-191Cell.2018, 172(1-2):249-261Food Research International2020, 108987Universidade Estadual Paulista2017, 42785J of App. Res. on Med&Aromatic Plants2020, 100291.Plant Direct.2021, 5(12):e372. Mie University2019, 10076.
Related Screening Libraries
| Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
|
Related Libraries |
Triterpenoids Compound Library |
| Description: |
Wilforol A is a natural product from Tripterygium wilfordii Hook. f. |
Wilforol A Description
| Source: |
The herbs of Tripterygium wilfordii Hook. f. |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
2.1432 mL |
10.7158 mL |
21.4316 mL |
42.8633 mL |
53.5791 mL |
| 5 mM |
0.4286 mL |
2.1432 mL |
4.2863 mL |
8.5727 mL |
10.7158 mL |
| 10 mM |
0.2143 mL |
1.0716 mL |
2.1432 mL |
4.2863 mL |
5.3579 mL |
| 50 mM |
0.0429 mL |
0.2143 mL |
0.4286 mL |
0.8573 mL |
1.0716 mL |
| 100 mM |
0.0214 mL |
0.1072 mL |
0.2143 mL |
0.4286 mL |
0.5358 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
| Structure Identification: |
| J Am Chem Soc. 2015 Sep 23;137(37):11864-7. | | Total Synthesis of Celastrol, Development of a Platform to Access Celastroid Natural Products.[Pubmed: 26331410 ] | Celastroid natural products, triterpenes, have been and continue to be investigated in clinical trials.
METHODS AND RESULTS:
Celastrol, and for that matter any member of the celastroid family, was prepared for the first time through chemical synthesis starting from 2,3-dimethylbutadiene. A triene cyclization precursor generated in 12 steps underwent a nonbiomimetic polyene cyclization mediated by ferric chloride to generate the generic celastroid pentacyclic core.
CONCLUSIONS:
In the cyclization, engagement of a tetrasubstituted olefin formed adjacent all carbon quaternary centers stereospecifically. With access to the carbocyclic core of the family of natural products, wilforic acid and Wilforol A were prepared en route to racemic celastrol. |
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