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    Natural Products
    Wilforol A
    Information
    CAS No. 167882-66-8 Price
    Catalog No.CFN92083Purity>=98%
    Molecular Weight466.6Type of CompoundTriterpenoids
    FormulaC29H38O5Physical DescriptionPowder
    Download     COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
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    Wilforol A

    Wilforol A
    Product Name Wilforol A
    CAS No.: 167882-66-8
    Catalog No.: CFN92083
    Molecular Formula: C29H38O5
    Molecular Weight: 466.6 g/mol
    Purity: >=98%
    Type of Compound: Triterpenoids
    Physical Desc.: Powder
    Source: The herbs of Tripterygium wilfordii Hook. f.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price:
    Inquire / Order: manager@chemfaces.com
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  • Molecules.2016, 21(6)
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    Description: Wilforol A is a natural product from Tripterygium wilfordii Hook. f.
    Wilforol A Description
    Source: The herbs of Tripterygium wilfordii Hook. f.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.1432 mL 10.7158 mL 21.4316 mL 42.8633 mL 53.5791 mL
    5 mM 0.4286 mL 2.1432 mL 4.2863 mL 8.5727 mL 10.7158 mL
    10 mM 0.2143 mL 1.0716 mL 2.1432 mL 4.2863 mL 5.3579 mL
    50 mM 0.0429 mL 0.2143 mL 0.4286 mL 0.8573 mL 1.0716 mL
    100 mM 0.0214 mL 0.1072 mL 0.2143 mL 0.4286 mL 0.5358 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    J Am Chem Soc. 2015 Sep 23;137(37):11864-7.
    Total Synthesis of Celastrol, Development of a Platform to Access Celastroid Natural Products.[Pubmed: 26331410 ]
    Celastroid natural products, triterpenes, have been and continue to be investigated in clinical trials.
    METHODS AND RESULTS:
    Celastrol, and for that matter any member of the celastroid family, was prepared for the first time through chemical synthesis starting from 2,3-dimethylbutadiene. A triene cyclization precursor generated in 12 steps underwent a nonbiomimetic polyene cyclization mediated by ferric chloride to generate the generic celastroid pentacyclic core.
    CONCLUSIONS:
    In the cyclization, engagement of a tetrasubstituted olefin formed adjacent all carbon quaternary centers stereospecifically. With access to the carbocyclic core of the family of natural products, wilforic acid and Wilforol A were prepared en route to racemic celastrol.
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