Hot Products
| Catalog No. | Information |
| CFN92315 | Epinodosin Epinodosin induces significant DNA damage to HepG2 cells in a time- and dose-dependent manner.Epinodosin has a biphasic, dose-dependent effect on root growth and a strong inhibitory effect on root hair development in Lactuca sativa L. seedlings. |
| CFN80044 | Epipinoresinol-4-O-beta-D-glucoside Reference standards. |
| CFN99283 | Epivogeloside Epivogeloside is a product from Lonicera japonica. |
| CFN70306 | Epoxybergamottin Epoxybergamottin is an inhibitor of CYP3A4, it also displays significant inhibition of superoxide anion generation and elastase release. |
| CFN98559 | Epoxylathyrol Epoxylathyrol derivatives have modulation of ABCB1-mediated multidrug resistance in human colon adenocarcinoma and mouse T-Lymphoma cells. |
| CFN91038 | Epoxymicheliolide Epoxymicheliolide, a novelguaiane-type sesquiterpene lactone, inhibits NF‑κB/COX‑2 signaling pathways by targeting leucine 281 and leucine 25 in IKKβ in renal cell carcinoma, it may be a novel anticancer agent in the treatment of renal cell carcinoma. |
| CFN97067 | epsilon-Viniferin Epsilon-Viniferin is a bacteriostatic stilbenoid as it antagonized the bactericidal activity of vancomycin. Epsilon-viniferin shows a human cytochrome P450 enzymes inhition activity, it exhibits good antioxidant capacity in the DMSO/O(-)(2) polar system (IC50= 0.14 mM). Epsilon-viniferin and epsilon-viniferin pentaacetate slightly reduce cell proliferation but might protect from cell degenerescence.(-)-Trans-epsilon-viniferin is an inhibitor of noradrenaline and 5-hydroxytryptamine uptake and of monoamine oxidase activity, it may be of value as a structural template for the design and development of new antidepressant drugs. |
| CFN60178 | Erastin |
| CFN90049 | Ergocalciferol Ergocalciferol (Vitamin D2) is a selective inhibitor of mammalian DNA polymerase A (pol A) with IC50 of 123 mM. Ergocalciferol can delay the development of secondary hyperparathyroidism in children with CKD2-3. Ergocalciferol can cause HL-60 apoptosis via a modulation of mitochondria involving ROS production, GSH depletion, caspase activation, and Fas induction, on the basis of anticancer activity of ergocalciferol, it may be feasible to develop chemopreventive agents from edible mushrooms or hop. Ergocalciferol can prevent glucocorticoid-induced bone loss, but even increase lumbar spine and femoral neck bone mineral densities (BMD) in postmenopausal women commencing glucocorticoid therapy, it also is safe and effective in reducing the risk of a fracture in elderly patients with AD. |
| CFN99889 | Ergosta-4,6,8(14),22-tetraen-3-one Ergosta-4,6,8(14),22-tetraen-3-one has cytotoxic activity against human gastric cancer cell, it can induce G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells, these results would be useful for the further utilization of many medicinal fungi in cancer treatment. Ergosta-4,6,8(14),22-tetraen-3-one treatment can confer protection against early renal injury in a rat model of aristolochic acid (AA) nephropathy, early administration of it may prevent the progression of renal injury and the subsequent renal fibrosis in AA nephropathy. It has inhibitory activity of nitric oxide production in RAW 264.7 cells stimulated by lipopolysaccharide was examined and shows a potential activity with the IC(50) value of 28.96 microM. |
