Hot Products
| Catalog No. | Information |
| CFN98535 | Digitoxin The cardiac glycosides digitoxin and digoxin have been used in cardiac diseases for many years, digitoxin also has growth inhibition activity in three human cancer cell line, digitoxin activates pro-apoptotic, anti-proliferative signaling cascades and cell cycle arrest. Digitoxin could as a candidate drug for suppressing IL-8-dependent lung inflammation in cystic fibrosis (CF), it can suppress hypersecretion of IL-8 from cultured cystic fibrosis (CF) lung epithelial cells, the specific mechanism is to block phosphorylation of the inhibitor of NF-kappa.Digitoxin actively inhibits Herpes simplex virus type 1 (HSV-1) replication with a 50% effective concentration (EC(50)) of 0.05 microM, the inhibitory effects of digitoxin are likely to be introduced at the early stage of HSV-1 replication and the virus release stage. |
| CFN98536 | Digoxin Digoxin is a classical Na,K-ATPase inhibitor, with selectivity for the α2β3 isoform over the common α1β1 isoform, used in the treatment of atrial fibrillation and heart failure. Digoxin and other cardiac glycosides can inhibit hypoxia-inducible factor 1 (HIF-1)α synthesis and block tumor growth. |
| CFN96580 | Dihydroactinidiolide Dihydroactinidiolide, a high light-induced β-carotene derivative that can regulate gene expression and photoacclimation in Arabidopsis. Dihydroactinidiolide has shown to be a potent phytotoxin at low concentration, it may have interesting potential anticancer activity. |
| CFN93295 | Dihydroartemisinic acid Dihydroartemisinic acid is a precursor to the antimalarial agent artemisinin. |
| CFN99507 | Dihydroartemisinin Dihydroartemisinin is widely used as an intermediate in the preparation of other artemisinin-derived antimalarial drugs, recommended as the first-line anti-malarial drug with low toxicity. Dihydroartemisinin has anticancer activity, it inhibited cell proliferation via AKT/GSK3β/cyclinD1/ERK pathway and induced apoptosis is associated with inhibition of Sarco/Endoplasmic reticulum Calcium ATPase activity in colorectal cancer. |
| CFN93796 | Dihydrobaicalein Dihydrobaicalein is a natural product from Scutellaria baicalensis Georgi. |
| CFN90431 | Dihydroberberine Dihydroberberine has anti-tumor activity. It also improves in vivo efficacy in terms of counteracting increased adiposity, tissue triglyceride accumulation, and insulin resistance in high-fat-fed rodents, thus is potential therapeutic reagents for type 2 diabetes treatment. |
| CFN99918 | Dihydrocapsaicin Dihydrocapsaicin, a potential inducer of autophagy, has cytotoxic activity. It has anti-atherogenic activity, can reduce the susceptibility of low-density lipoprotein (LDL) to oxidation. Dihydrocapsaicin treatment depletes peptidergic nerve fibers of substance P and alters mast cell density in the respiratory tract of neonatal sheep. |
| CFN90127 | Dihydrochelerythrine Dihydrochelerythrine has antifungal activity against pathogenic plant fungi; it shows antiparasitic efficacy against Ichthyophthirius multifiliis in richadsin, it has potential application in the therapy of serious infection caused by I. multifiliis. Dihydrochelerythrine affects cell cycle distribution, activates mitochondrial apoptotic pathway, and induces apoptosis and necrosis in HL-60 cells. |
| CFN90608 | Dihydrocholesterol Dihydrocholesterol is a cholesterol derivative found in human feces, gallstones, eggs, and other biological matter. Dihydrocholesterol is equally effective in reducing plasma cholesterol as β-sitosterol at a low dose, which is mediated by inhibiting the cholesterol absorption and increasing the fecal sterol excretion. |
