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Natural Products
Catalog No. Information
CFN98962 Engeletin

Engeletin, a bioactive flavonoid, has multiple biological activities such as anti-diabetic and anti-inflammatory effects. Engeletin possesses potent inhibition of PGE2 release with IC50 values of 19.6 μg/ml; it inhibits a recombinant human aldose reductase (IC50 value=1.16 microM).
CFN70257 Englerin A

Englerin A, a selective inhibitor of renal cancer cell growth, it is a therapeutic lead for the treatment of renal cell carcinoma. Englerin A induces an acute inflammatory response and reveals lipid metabolism and ER stress as targetable vulnerabilities in renal cell carcinoma.
CFN92435 Enmein

Enmein shows significant inhibitory effect toward human tumor cell K562 with IC(50) values ranging from 3.2 microg/ml to 8.2 microg/ml, it shows antitumour activity against Ehrlich ascites carcinoma and is active against gram-positive bacteria. Enmein has distinct immunosuppressive effect in vitro and in vivo systems, it depresses the murine ear swelling extent and the level of Interleukin-2 in blood serum in a dose-dependent manner.
CFN97986 Enniatin B1

Enniatin B1 has antifungal effects. It induces apoptotic cell death in H4IIE hepatoma cells accompanied by inhibition of ERK phosphorylation. Enniatin B1 also has intestinal toxicity.
CFN99290 ent-14,16-Epoxy-8-pimarene-3,15-diol

Reference standards.
CFN98424 ent-16beta,17-Dihydroxy-19-kauranoic acid

Reference standards.
CFN91664 Entadamide A

Entadamide A has anti-inflammatory, anti-oxidative stress activity.
CFN70448 Enterodiol

Enterodiol has antioxidant and immunomodulatory effects, it is able to pass the intestinal barrier and modulate cytokine production, it prevented inhibitory-kappaB (I-kappaB) degradation and nuclear factor-kappaB (NF-kappaB) activation, which in turn resulted in decreased tumor necrosis factor-alpha (TNF-alpha) production.Enterodiol inhibited the growth of CRC cells by controlling the MAPK signaling pathway involved in proliferation and apoptosis.
CFN70450 Enterolactone

Enterolactone( Enl ) has chemopreventive action, it suppresses colo 201 human colon cancer cell growth both in vitro and in vivo. Enl may affect the growth of these estrogen sensitive cells is by competition of Enl and its sulfate with the estrogens for sulfokinases and sulfatases involved in estrogen metabolism in the cells. Enl acts as a weak aromatase inhibitor in vitro and to reduce the relative uterine weight of the 7,12-dimethylbenz(a)anthracene-treated nonovariectomized rats.
CFN97033 ent-Kauran-17,19-dioic acid

Reference standards.