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Natural Products
Catalog No. Information
CFN92367 Inotodiol

Inotodiol shows significant anti-tumor and anti-tumor promoting activities, including human cervical cancer, it inhibits cell proliferation through apoptosis induction by activating caspase-3. Inotodiol can inhibit proliferation and induce the apoptosis of A549 cells, and its molecular mechanism may be associated with the up-regulating expression of p53 and bax proteins and down-regulating expression of Bcl-2 protein, which arrested A549 cells in S phase.
CFN00419 Integerrimine

Prenatal exposure to Integerrimine N-oxide induces maternal toxicity, impairment of maternal care and delayed in physical and behavioral development of the offspring. Doses of Integerrimine N-oxide here employed did not produce marked immunotoxic effects.
CFN00458 Integerrimine N-oxide

CFN00285 Intermedine

Intermedin (IMD), a multi-functional peptide, plays important roles in cardiovascular protection, the endogenous IMD and its receptor complexes are induced in hypertrophic cardiomyocytes and proposed to play an important role in the pathogenesis of cardiac hypertrophy. Intermedin can decrease the melanin content of the skin of Rana pipiens.
CFN00459 Intermedine N-oxide

CFN96557 Iridin

CFN98864 Iriflophenone

Standard reference
CFN99063 Iriflophenone 3-C-beta-D-glucopyranoside

Iriflophenone-3-C-β-d-glucoside shows potent inhibitory activity against α-glucosidase. Iriflophenone 3-C-β-D-glucoside and mangiferin which along with 3 β taraxerol and other sterols could be contributing to the cholesterol lowering activity. Iriflophenone-3- C -glucoside has antioxidant activity, it presents no radical scavenging ability against DPPH , but scavenges ABTS + and peroxyl radicals (TEAC ABTS of 1.04 and TEAC ORAC of 3.61).
CFN93276 Irigenin

Irigenin, an α-glucosidase inhibitor, which has anti-inflammatory, anti-cancer, and anti-metastatic effects. Irigenin can inhibit the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX)-2 proteins and mRNAs without an appreciable cytotoxic effect. Irigenin displays moderate activity as inducers of NAD(P)H:quinone reductase (QR) in cultured mouse Hepa 1c1c7 cells.
CFN93694 Irilone

Irilone has immunomodulatory, and α-amylase inhibitory activities, it exhibits the selective inhibition toward CYP3 A4 rather than other major human CYPs. Irilone exhibited prominent antioxidant activities with the IC50 value of 10.46μM. Irilone potentiated the effect of progesterone in both endometrial and ovarian cancer cell lines, it protected dopaminergic neurons against LPS-induced injury through inhibition of microglia activation and proinflammatory factors generation.