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Natural Products
Catalog No. Information
CFN99200 Hypaconitine

Hypaconitine, an active and highly toxic constituent derived from Aconitum species, has anti-inflammatory activity, is widely used to treat rheumatism. It produced neuromuscular blockade by reducing the evoked quantal release, the mechanism of this effect was attributed mainly to blocking of the nerve compound action potential.
CFN90634 Hypaphorine

Hypaphorine is an indole-3-acetic acid antagonist which specifically compete with indole-3-acetic acid in binding to the indole-3-acetic acid-binding site in plant peroxidases.Hypaphorine and endogenous indole-3-acetic acid counteract in controlling root hair elongation.
CFN91083 Hyperforin

Hyperforin acts as an angiogenesis inhibitor, it as a possible antidepressant component of hypericum extracts. Hyperforin acts as a dual inhibitor of 5-LO and COX-1 in intact cells as well as on the catalytic activity of the crude enzymes, suggesting therapeutic potential in inflammatory and allergic diseases connected to eicosanoids.
CFN99188 Hypericin

Hypericin is a photosensitive antiviral with anticancer and antidepressant agent . It can inhibit tyrosine kinases with IC50 of 7.5 μM. It can induce both apoptosis and necrosis in a concentration and light dose-dependent fashion, and inhibit RANKL-mediated osteoclastogenesis via affecting ERK signalling in vitro and suppresses wear particle-induced osteolysis in vivo.
CFN98754 Hyperoside

Hyperoside, a naturally occuring flavonoid compound, exerts multiple bioactivities, including myocardial protection, anti-redox, neuroprotective, antifungal, hepatoprotective, anti-inflammatory and antioxidative effects. Hyperoside is a potent natural activator of Nur77 receptor, and a potent selective CYP2D6 inhibitor; it inhibited the HMGB1 signaling pathway, and inhibited the PI3K/Akt/Bad/Bcl XL -regulated mitochondrial apoptotic pathway. Hyperoside is a strong inhibitor of HBsAg and HBeAgsecretion in 2.2.15 cells and DHBV-DNA levels in the HBV-infected duck model.
CFN92439 Hypocrellin A

Hypocrellin A, an a natural perylene quinine photosensitizers (PSs), can chelate with heavy metal ions, including Au(III) and Pt(IV), to form a 1:2 complex. Hypocrellin A has light-induced antitumor,antifungal and antiviral activities, it also exerts immunomodulatory effects on MHC-restricted presentation of antigen.
CFN91775 Hyponine D

Hyponine D is an immunosuppressive.
CFN91777 Hyponine E

Hyponine E possesses anti-inflammatory effects.
CFN98431 Hypophyllanthin

Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice. Hypophyllanthin can modulate the vascular tension via the endothelium-independent mechanisms, it can directly inhibit P-gp activity and does not interfere with MRP2 activity, it may reversibly inhibit P-gp function. Hypophyllanthin offers a promising means for treatment of chronic muscle pain. Hypophyllanthin also has estrogenic properties against carbofuran induced toxicity in female rats.
CFN96592 Hypoxanthine

Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.Hypoxanthine inhibits mouse oocyte maturation, it plays a role in vivo in maintaining meiotic arrest.