Hot Products
| Catalog No. | Information |
| CFN97415 | Hythiemoside A Reference standards. |
| CFN89402 | Hyuganin D Hyuganin D can inhibit LPS-induced NO and/or TNF-alpha production in mouse peritoneal macrophages. |
| CFN97329 | Ibogaine Ibogaine has promising anti-addictive property in animals. It has the propensity to prolong the QT interval of the electrocardiogram in humans, may generate life-threatening cardiac arrhythmias. |
| CFN60061 | Ibrutinib (PCI-32765) Ibrutinib (PCI-32765) is a potent and highly selective Brutons tyrosine kinase (Btk) inhibitor with IC50 of 0.5 nM in cell-free assays, modestly potent to Bmx, CSK, FGR, BRK, HCK, less potent to EGFR, Yes, ErbB2, JAK3, etc. Ibrutinib is applicable as a Btk ligand in the synthesis of a series of PROTACs including P13I. |
| CFN99554 | Icariin Icariin inhibits PDE5 and PDE4 activities with IC50s of 432 nM and 73.50 μM, respectively. Icariin also is a PPARα activator. Icariin has been reported to have anti-hypoxic, phytoestrogenic, anti-osteoporotic, anti-inflammatory, neuroprotective, and anti-depressant-like activities. Icariin is effective in the attenuation of AHR and chronic airway inflammatory changes in OVA-induced murine asthma model, and this effect is associated with regulation of Th17/Treg responses. Icariin inhibited NF-κB signaling activation and the NLRP3-inflammasome/caspase-1/IL-1β axis. |
| CFN96968 | Icariside B1 Icariside B1 shows inhibitory effects on LPS-induced NO production in RAW264.7 cells. |
| CFN96912 | Icariside D2 Icariside D2 shows significant cytotoxic activity on the HL-60 cell line with the IC50 value of 9.0 ± 1.0 uM, it induces apoptosis via alteration of expression of apoptosis-related proteins and decreased phosphorylation of AKT in HL-60 cells. |
| CFN99373 | Icariside E5 Icariside E5 may have antioxidant property that strengthen the importance of peppers in the Mediterranean diet. |
| CFN92550 | Icariside I Icariside I is a metabolite product of Icariin. |
| CFN98527 | Icaritin Icaritin, a potent inhibitor of transcription factor SREBPs, which exhibits a variety of biological activities, such as activation of cancer cell apoptosis and inhibition of growth, hormone regulation, protection against beta amyloid-induced neurotoxicity, and promotion of neuronal and cardiac cellular differentiation. Icaritin shows potent anti-leukemia activity on chronic myeloid leukemia in vitro and in vivo by regulating MAPK/ERK/JNK and JAK2/STAT3 /AKT signalings. |
