Hot Products
| Catalog No. | Information |
| CFN70149 | L-Glutamine L-Glutamine prevents acetaldehyde-induced disruption of the tight junction and increase in the paracellular permeability in Caco-2 cell monolayer by an EGF receptor-dependent mechanism. It prevents oxidant- or endotoxin-induced death of neonatal enterocytes. |
| CFN91725 | L-Histidine L-Histidine is an essential amino acid for infants. L-Histidine is an inhibitor of mitochondrial glutamine transport.L-Histidine is also required for blood cell manufacture and protects tissues against damage caused by radiation and heavy metals. IC50 & Target: Microbial Metabolite; Human Endogenous Metabolite |
| CFN91727 | L-Hydroxyproline L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals. IC50 & Target: Human Endogenous Metabolite |
| CFN98244 | Licarin A Licarin A and (-)-Licarin A are promising compounds that could be used for the development of schistosomicidal and trypanocidal agents; Licarin A presents effect against Leishmania (Leishmania) major associated with immunomodulation in vitro; (-)-Licarin A has antimycobacterial activity, represents a potentially active anti-tuberculosis agent to treat MDR M. tuberculosis and NTM strains.Licarin A significantly protects primary cultured neuronal cells against glutamate-induced oxidative stress, via antioxidative activities. |
| CFN95072 | Licoarylcoumarin Licoarylcoumarin is a strong inhibitor of adenosine 3',5'-cyclic monophosphate (cAMP) phosphodiesterase. Licoarylcoumarin has antibacterial effects on the VRE strains; it has anti-HIV activity, and it has inhibitory effects on xanthine oxidase. |
| CFN99575 | Licochalcone A Licochalcone A is an estrogenic flavanoid extracted from licorice root, showing antimalarial, antileishmanial, anticancer, anti-inflammatory, antibacterial and antiviral activities. It could be a promising strategy in treating osteoporotic weight-bearing bones fractures with defects, and be a useful compound for the development of antibacterial agents for the preservation of foods containing high concentrations of salts and proteases, in which cationic peptides might be less effective. |
| CFN99576 | Licochalcone B Licochalcone B has antitumor, antimetastatic, cardioprotective, antioxidant, antiapoptotic, and anti-inflammatory effects, it can significantly inhibit LPS-induced phosphorylation at serine 276 and transcriptional activation of NF-KB. Licochalcone B can protect the liver from carbon tetrachloride (CCl4)-induced injury, the protection may be due to inhibition of p38 and NFκB signaling, which subsequently reduces inflammation in the liver. |
| CFN99577 | Licochalcone C Licochalcone C has cardioprotection effect, via antioxidant, anti-inflammatory, and anti-apoptotic activities; it shows inhibition of bacterial growth and cellular respiration. Licochalcone C exhibits inhibitory activity with cytotoxicity in a rat basophilic leukemia cell line, RBL-2H3. It induces apoptosis via B-cell lymphoma 2 family proteins in T24 cells, it may be a potential adjuvant therapeutic agent for bladder cancer. |
| CFN93186 | Licochalcone D Licochalcone D has anti-inflammatory, and anti-allergic activities, it shows suppression ability of nitric oxide (NO) production, it also suppresses degranulation by decreasing the intracellular Ca2+ level and tyrosine phosphorylation of ERK in RBL-2H3 cells. Licochalcone D has cardioprotective potential against myocardial ischemia/reperfusion injury in langendorff-perfused rat hearts. It may be a potential drug for human melanoma treatment by inhibiting proliferation, inducing apoptosis via the mitochondrial pathway and blocking cell migration and invasion. |
| CFN93297 | Licochalcone E Licochalcone E is a potential LXRβ agonist, which has chemopreventive, cytotoxic, anti-inflammatory, antimicrobial, antidiabetic effects; it increases the levels of PPARγ expression, at least in part, via the stimulation of Akt signals and functions as a PPARγ partial agonist. Licochalcone E may be used for the treatment of hepatotoxicity, and primarily exhibits its protective role through a PPARγ/NF-κB-mediated pathway. Licochalcone E is also a potential activator of the Nrf2/ARE-dependent pathway and is therapeutically relevant not only to oxidative-stress-related neurodegeneration but also inflammatory responses of microglial cells both in vitro and in vivo. |
