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Catalog No. Information
CFN70276 Oleacein

Oleacein has antioxidant, anti-metastatic, anticancer, and anti-inflammatory activities, it inhibits STAT3, activates the apoptotic machinery. Oleacein can be used as an adjuvant to improve insulin sensitivity in humans, and it could play a potential role in the prevention of inflammatory disease related to atherosclerosis.
CFN98871 Olean-12-ene-3,11-diol

Reference standards.
CFN98693 Oleandrin

Oleandrin has anticarcinogenic, anti-inflammatory, and growth-modulatory effects , which may thus be partially ascribed to the inhibition of activation of NF-κB and AP-1 and potentiation of apoptosis; it has stronger anti-proliferative activity in undifferentiated CaCO-2 cells (IC50, 8.25 nM) , causes an autophagic cell death and altered ERK phosphorylation in undifferentiated.Oleandrin inhibits the Na+, K+-ATPase activity with an IC50 of 620 nM.
CFN98800 Oleanolic acid

Oleanolic acid is a non-toxic, hepatoprotective triterpenoid found in Phytolacca Americana, which exerts antitumor, anti-inflammatory, antioxidant, and antiviral properties. Oleanolic acid exhibits anti-HCV activity at least partly through suppressing HCV NS5B RdRp activity as a noncompetitive inhibitor; it induces the upregulation of miR-132, which serves as an important regulator of neurotrophic actions, mainly through the activation of the hippocampal BDNF-ERK-CREB signalling pathways; can be employed as a lead in the development of potent NO inhibitors. Oleanolic acid supplement ameliorates fructose-induced Adipo-IR in rats via the IRS-1/phosphatidylinositol 3-kinase/Akt pathway.
CFN90884 Oleaside A

Oleaside A is a natural product from Nerium oleander.
CFN94800 Oleic acid

Oleic acid is a fatty acid that occurs naturally in various animal and vegetable fats and oils. It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent. It shows larvicidal effects against fourth instar larvae of Aedes aegypti L. , Anopheles stephensi Liston , and Culex quinquefasciatus Say.
CFN70331 Oleocanthal

Oleocanthal as anti-inflammatory therapeutic agent, it shows inhibition of MIP-1α and IL-6 in J774 macrophages and in ATDC5 chondrocytes. Oleocanthal and its derivatives can decrease lipopolysaccharide-induced NOS2 synthesis in chondrocytes without significantly affecting cell viability at lower concentrations.Oleocanthal abrogates fibrillization of tau by locking tau into the naturally unfolded state.
CFN99838 Oleoside

Oleacein is a strong Angiotensin Converting Enzyme (ACE)-inhibitor (IC50 = 26 uM).
CFN95441 Oleracein E

Oleracein E (OE), a tetrahydroisoquinoline, has potent antioxidant and anti-apoptotic activities. Olivine E is cardioprotective and neuroprotective.Oleracein E has the effect of improving cognitive function. Oleracein E exhibits moderate antibacterial activity. Oleracein E showed significant cytotoxicity against HepG2,with its inhibitory rate of 52.2% at 10 micromol x L(-1). Oleracein E has an osteogenic effect. TRP-1 (Oleracein E) strongly accelerates the Treg proliferation in vitro in a concentration-dependent manner.
CFN98416 Oleuropein

Oleuropein exhibits anti-ischemic, antioxidative, hypolipidemic, in vitro antimycoplasmal , anti-inflammatory, and anti-cancer effects., it also may be helpful in the prevention of diabetic complications associated with oxidative stress. Oleuropein prevents oxidative myocardial injury induced by ischemia and reperfusion, and reduces viremia in duck hepatitis B virus (DHBV)-infected ducks. Oleuropein reduces TLR and MAPK signaling.