Hot Products
Catalog No. | Information |
CFN92341 | Pallidol Pallidol is a potent and selective singlet oxygen quencher in aqueous systems, it may be used in singlet oxygen-mediated diseases as a pharmacological agent. |
CFN98459 | Palmatine Palmatine shows significant antidepressant-like, anti-hyperlipidemia, hepatoprotective, and antioxidant effects, it inhibited MAO-A, I(K) and I(CRAC) activity, and activated the AhR-CYP1A pathway. Palmatine shows the strong toxic action on T. thermophila BF5 growth, it is toxic to insects and vertebrates and inhibited the multiplication of bacteria, fungi and viruses, it is active at the alpha 2-receptor ( IC50 of 956 nM). |
CFN99124 | Palmatine hydrochloride Palmatine hydrochloride is a hydrochloride salt of palmatine which is a protoberberine alkaloid, it can induce remarkable cell apoptosis, has potential in photodynamic therapy on colon adenocarcinoma. Palmatine hydrochloride has anti-C. albicans effect, it mixes with berberine hydrochloride elicit antifungal activities, it also can reduce blood sugar and oxidative stress in STZ induced diabetic rats. |
CFN90505 | Palmatrubine Palmatrubine binds to double-stranded DNA most probably via an intercalating mode. |
CFN99716 | Palmitic acid Palmitic acid induces anxiety-like behavior in mice while increasing amygdala-based serotonin metabolism, it induces down-regulation of APOM expression, is mediated via the PPARβ/δ pathway. Palmitic acid induces degeneration of myofibrils and modulate apoptosis in rat adult cardiomyocytes. it also shows in vivo antitumor activity in mice. Palmitic acid is CNS mediated via PKC-theta activation, resulting in reduced insulin activity. |
CFN97010 | Palustrol Palustrol exhibits acaricidal, insecticidal, ‘pesticidal’ and/or arthropod repellent properties, may be useful sources of chemicals for the control of arthropods of medical, veterinary or agricultural importance. |
CFN93082 | Panasenoside Reference standards. |
CFN99981 | Panaxadiol Panaxadiol, an anti-hepatitis B virus inhibitor, exhibits anticancer, cardioprotective, anti-arrhythmic, and antioxidative activities. It inhibits Ca2+ channels, decreasing channel open time and open state probability in vitro and displaying anti-arrhythmic potential. Panaxadiol selectively interferes with the cell cycle in human cancer cell lines, it inhibits DNA synthesis in a dose-dependent manner with IC50 values ranging from 0.8 to 1.2 μM in SK-HEP-1 cells and HeLa cells, it selectively elevates p21WAF1/CIP1 levels and thereby arrests the cell cycle at G1/S phase by down-regulating Cyclin A–Cdk2 activity. |
CFN99982 | Panaxatriol Panaxatriol is an inducer of thioredoxin-1 (Trx-1), which exhibits anti-inflammatory, hepatoprotective, anti-arrhythmic, and antioxidative activities. It has pluripharmacological properties in the protection against Parkinson's disease (PD) including enhancing antioxidant activity, acting as neurotrophic factor, modulating inflammation and inhibiting mitochondria-mediated apoptosis. Panaxatriol has been shown to be efficacious in the prevention and treatment of cerebrovascular diseases in China, it may activate endogenous cytoprotective mechanism against OGD-Rep induced oxidative injury via the activation of PI3K/Akt and Nrf2 signaling pathway. |
CFN92798 | Panaxydiol Panaxydiol can inhibit rat liver cholesterol acyltransferase (ACAT) with IC50 values of 45 microM. |