Hot Products
| Catalog No. | Information |
| CFN90169 | Pristimerin Pristimerin is a naturally occurring triterpenoid that has been shown to suppress the proliferation of various cancer cell lines at the concentration (IC50) range of 0.2-4 μM, including those of breast, glioma, prostate, pancreatic, ovarian, colon. Pristimerin exhibits inhibitory effects against diverse phytopathogenic fungi, it shows good preventive effect and curative effect against wheat powdery mildew in vivo. It has a wide spectrum of targets including ROS, IKK, NF-κB, Akt, mTOR, Bcr-Abl. |
| CFN99556 | Proanthocyanidins Proanthocyanidins exerts antiviral, hepatoprotective, cardioprotective, hypolipidemic, anti-osteoporosis, anti-inflammatory ,antioxidant and anti-apoptosis activities. Dietary proanthocyanidins inhibits photocarcinogenesis in mice through the inhibition of UVB-induced inflammation and mediators of inflammation in mouse skin. Proanthocyanidins form stable complexes with metal ions and with proteins and are good reducing agents, they may participate in the prevention of cancers, both of the digestive tract and inner organs, they may also protect LDLs against oxidation and inhibit platelet aggregation and therefore prevent cardiovascular diseases. |
| CFN94479 | Procaine Procaine is a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. It is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells, it inhibits the Wnt canonical pathway by promoter demethylation of WIF-1 in lung cancer cells. |
| CFN96021 | Procumbide Procumbide has anti-inflammatory activity. |
| CFN92647 | Procurcumenol Procurcumenol is an inhibitor of Nitric Oxide. Procurcumenol and epicurcumenol have inhibitory effects on release of tumor necrosis factor-a (TNF-a). |
| CFN96495 | Procyanidin A1 Procyanidin A1 has antiallergic effects, it inhibits degranulation downstream of protein kinase C activation or Ca2⁺ influx from an internal store in RBL-2H3 cells. Procyanidin A1 shows a very high inhibition effect on LDL oxidation, with the IC50 value of 0.94 uM. |
| CFN96491 | Procyanidin A2 Procyanidin A2 is a potential precursor of 5-(3',4'-dihydroxyphenyl)-γ-valerolactone, exhibits antioxidant, anti-inflammary, anti-hyperglycemia, and anti-type 2 diabetes activities. Procyanidin A2 demonstrates liver cell regenerative activity in scratch wound healing assays and alcohol-induced liver cell injury in vitro. |
| CFN99557 | Procyanidin B1 Procyanidin B1, a HCV RNA polymerase inhibitor, inhibits infection by vesicular stomatitis virus and HCV pseudotype virus in Huh-7 cells, with IC50 of 29μM and 15μM, respectively. Procyanidin B1 has neuroprotective effects, may attenuate the activation of caspase-3 by inhibiting that of caspase-8 and -9. It has anti-inflammatory effect on LPS-treated THP1 cells via interaction with the TLR4–MD-2 heterodimer and p38 MAPK and NF-κB signaling. |
| CFN99558 | Procyanidin B2 Procyanidin B2 has vascular protective, anti-diabetic nephropathy,anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inflammasome activation via suppression of AP-1 pathway, and up-regulated the expression of GSTP1 via a mechanism that involves ERK and p38 MAPK activation and Nrf2 translocation. It has anti- and pro-oxidant effects on metal-mediated DNA damage by interacting with H2O2 and metal ions. |
| CFN99559 | Procyanidin B3 Procyanidin B3(B3) is a procyanidin dimer that is widely studied due to its high abundance in the human diet and antioxidant activity. Procyanidin B3 is an inhibitor of histone acetyltransferase, B3 enhances the action of antagonist for prostate cancer cells via inhibition of p300-dependent acetylation of androgen receptor. Procyanidin B3 prevents osteoarthritis (OA) progression and heterotopic cartilage formation, at least in a part through the suppression of iNOS, these results support the potential therapeutic benefits of B3 for treatment of human OA and heterotopic ossification. |
