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Natural Products
Catalog No. Information
CFN80311 Saikosaponin B3

Saikosaponin B3 shows some analgesic effect.
CFN93258 Saikosaponin B4

Saikosaponin B4 can selectively inhibit ACTH-induced lipolysis.
CFN99988 Saikosaponin C

Saikosaponin C exhibits anti-HBV activity, it has the potential for therapeutic angiogenesis but is not suitable for cancer therapy, it also might be a novel therapeutic tool for treating human AD and other neurodegenerative diseases. It inhibited caspase-3 activation and caspase-3-mediated-FAK degradation, induced matrix metalloproteinase-2 (MMP-2)、vascular endothelial growth factor (VEGF) 、the p42/p44 mitogen-activated protein kinase (MAPK, ERK).
CFN99989 Saikosaponin D

Saikosaponin D, a calcium mobilizing agent (SERCA inhibitor), is also an agonist of the glucocorticoid receptor (GR),which has anti-cancer, anti-inflammatory, and neuroprotective effects. Saikosaponin D protects against acetaminophen-induced hepatotoxicity by inhibiting NF-κB and STAT3 signaling; it shows inhibitory effects on NF-κB activation and thereby on iNOS, COX-2 and pro-inflammatory cytokines.
CFN93270 Saikosaponin E

Reference standards.
CFN90635 Saikosaponin F

Saikosaponin F shows anti-inflammatory effect against carrageenan-induced plantar oedema in the rat.
CFN90902 Saikosaponin H

Saikosaponin H is a natural product from Bupleurum chinense.
CFN98059 Sakakin

Orcinol glucoside(Sakakin) shows potent antioxidative and anxiolytic activities without sedative effects, it can improve depressive behaviour in chronic unpredictable mild stress (CUMS) rats by downregulating HPA axis hyperactivity and increasing BDNF expression and ERK1/2 phosphorylation in the hippocampus.
CFN98366 Sakuranetin

Sakuranetin, a flavanone phytoalexin from ultraviolet-irradiated rice leaves, it has antifungal, antimutagenic, anti-inflammatory and antioxidant effects, it shows a suppressive effect on umu gene expression of SOS response in Salmonella typhimurium TA1535/pSK1002 against the mutagen furylfuramide. Sakuranetin may contribute to maintain glucose homeostasis in animals, it can strongly induce differentiation of 3T3-L1 preadipocytes, stimulate glucose uptake in differentiated 3T3-L1 adipocytes.Sakuranetin stimulates melanogenesis in B16 melanoma cells via inhibition of ERK1/2 and PI3K/AKT signaling pathways, which lead to upregulation of Tyr, TRP1, and TRP2.
CFN91920 Salannin

Salannin has antifeedant and insect growth-regulating activities.Salannin also has anti-inflammatory activity,it exerts moderate inhibition (IC(50) values of 410-471 mol ratio/32 pmol TPA) of TPA-induced Epstein-Barr virus early antigen (EBV-EA) activation in Raji cells. Salannin inhibits ecdysone 20-monooxygenase (E-20-M) activity in a dose-dependent fashion.