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Natural Products
Catalog No. Information
CFN99103 Rosmarinic acid

Rosmarinic acid has antiviral, antibacterial, antiinflammatory, neuroprotective, anticancer, anti-lipid peroxidative, apoptotic,and antioxidant activities. It is used for food preservation, and to treat peptic ulcers, arthritis, cataract, cancer, rheumatoid arthritis, bronchial asthma, and several human neurodegenerative diseases caused by oxidative stress. Rosmarinic acid has the ability to block complement fixation, inhibit lipoxygenase and cyclooxygenase activity and inhibit the expression of CCL11 and CCR3 by suppressing the IKK-β activity in NF-κB activation signaling. It inhibits MAO-A, MAO-B and COMT enzymes with IC50s of 50.1, 184.6 and 26.7 μM, respectively.
CFN95297 Rosmarinyl glucoside

Anti-inflammatory effects of rosmarinic acid-4-O-β-D-glucoside in reducing acute lung injury in mice infected with influenza virus.
The scientists found a solution to make Rosmarinic acid available for skin care products. They used glycosylation to convert Rosmarinic acid into Rosmarinyl Glucoside, which is bioavailable, water-soluble and stable in formulations. After penetration trough skin barriers Rosmarinyl Glucoside disintegrates back into Rosmarinic acid. Its biologically active in cells with anti-ageing properties - protecting collagen and hyaluronic acid from destruction by inhibiting enzymes (collagen-destroying enzyme and hyaluronidase). Protects against the degradation of the cellular matrix and captures free-radicals.
A healing herb and one of the most well-known polyphenols for skincare, Rosmarinyl Glucoside guards skin’s extracellular matrix to maintain collagen and keep skin firm, strong and resilient. Its antioxidant activity captures the free radicals that damage skin and inhibit the breakdown of the hyaluronic acid that keeps skin hydrated, plumped, and refreshed.
CFN99365 Rosthornin B

CFN98590 Rotenone

Rotenone is a mitochondrial complex I inhibitor that produces an animal model of Parkinson's disease. Rotenone-induced α-synuclein aggregation is mediated by the calcium/GSK3β signaling pathway. Rotenone can increase intracellular levels of the toxic dopamine metabolite 3,4-dihydroxyphenyl-acetaldehyde (DOPAL), via decreasing DOPAL metabolism by aldehyde dehydrogenase (ALDH) and decreasing vesicular sequestration of cytoplasmic dopamine by the vesicular monoamine transporter (VMAT).
CFN99195 Rotundine

Rotundine provides remarkable protection against cerebral ischemia reperfusion damage, its mechanisms may be through its influence on NO、ET 1 and energy metabolism. Rotundine injection can ameliorate the damages by modulating the activities of different types of NOS. It combined with methadone treatment may be a better therapeutic method in treatment of heroin dependence.
CFN96006 Royleanone

Royleanone possesses cytotoxic activity against the human pancreatic cancer cell line MIA PaCa-2.
CFN99270 Rubiadin

Rubiadin has hepatoprotective, antioxidant, and antitumor promoting effects. Rubiadin can decrease bone loss through the inhibition of osteoclast formation,differentiation and bone resorption.
CFN97227 Rubiadin 1-methyl ether

Rubiadin-1-methyl ether probed as Type I photosensitizers. Rubiadin 1-methyl ether decreases the number of parasites (schizonts) in a dose-dependent manner, and 100% of inhibition was obtained with 30 to 40 micrograms. Rubiadin-1-methyl ether shows strong enhancing activity for adipocyte differentiation, it could be beneficial in the treatment of diabetes. Rubiadin-1-methyl ether has therapeutic potential against osteoporosis, it can promote osteoblast proliferation and inhibit osteoclast TRAP activity and bone resorption, and the inhibitory effects on osteoclastic bone, antiosteoporotic activity of M. officinalis .
CFN99393 Rubiarbonol B

Rubiarbonol B may have antiplatelet aggregation activities.
CFN92603 Rubinaphthin A

Rubinaphthin A is a natural product from Rubia cordifolia.