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  • Screening Libraries
    Chelidonium majus L.
    A unique collection of 22 Chelidonium majus L. for high throughput screening (HTS), high content screening (HCS) and New drug research
    Catalog No. Size Price Stock
    P203381mg/well * 22 CompoundsInquiry In stock
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    P20338100uL/well (10mM solution) * 22 CompoundsInquiry In stock
    *You can select compounds, quantities, format (dry/solid or DMSO) and plate map to meet your specific requirement.
    Contact Us
    E-mail manager@chemfaces.com
    Tel (0086)-27-8423-7683
    Shelf Life (0086)-27-84254680
    ManufacturerWuhan ChemFaces Biochemical Co., Ltd.
    Package & Storage
    Container 96 Well Format Sample
    Storage Protected from air and light, refrigerate or freeze(2-8 °)
    Shelf Life 24 months (2-8 °)
    Intended UseFor research use only. Not for human use. Not sell to patients
    Description & Advantages
    1. The products in the ChemFaces screening libraries are all from plants.
    2. The biological activities or pharmacological activities of all the ChemFaces products are derived from the databases of all over the world the latest literatures, you can according to the product manuals on our website to access the relevant literatures, hope that our informations can give some inspirations and help to your research.
    3.The collections of unique natural products, which include antioxidants, anti-inflammatory, antibacterial, anticancer, and ect. Can be used for high throughput screening (HTS) and high content screening (HCS), is to help you carry out new drug screening, the emergence of new indications and other professional tools.
    4.Structurally diverse, medicinally active, and cell permeable, NMR and HPLC validated to ensure high purity.
    5. ChemFaces offers customized bioactive screening libraries , whereby you choose the specific compounds you want in the library, the quantities, plate map, concentration, and format (dry/solid or DMSO solution).
    Natural Products
    Catalog No. Information
    CFN99564 Coptisine chloride

    Coptisine is an isoquinoline alkaloid isolated from Coptidis Rhizoma with anti-diabetic, antimicrobial, antiviral, anti-hepatoma, and anti-leukemia effects. Coptisine protects rat heart against myocardial ischemia/reperfusion injury by suppressing myocardial apoptosis and inflammation. Coptisine chloride can be absorbed across intestinal epithelial cells, and completely absorbed compounds.
    CFN99399 Protopine

    Protopine acts as a potent inhibitor of thromboxane synthesis and PAF with hepatoprotective, antidepressant, antioxidant, antispasmodic and relaxant properties. Protopine is also a novel microtubule-stabilizing agent, causes mitotic arrest and apoptotic cell death in human hormone-refractory prostate cancer cell lines. Protopine blocks phosphorylation of mitogen-activated protein kinases (MAP kinases) and also blocks activation of a nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB).
    CFN98980 Ergosterol

    Ergosterol is the primary sterol found in fungi, with antioxidative, anti-proliferative, and anti-inflammatory effects, ergosterol peroxide has the potential to be developed as a therapeutic agent to prevent renal fibrosis. Ergosterol can promote pheromone signaling and plasma membrane fusion in mating yeast, the critical requirement for ergosterol in V-ATPase function may underlie the antifungal activity of azoles.
    CFN98551 Citric acid

    Citric acid is a natural preservative and food tartness enhancer, it is also an Al-chelating substance and a natural antioxidant. Citric acid (1-2 g/kg) can decrease brain lipid peroxidation and inflammation, liver damage, and DNA fragmentation. Citric acid has phytoremediation of heavy metal contaminated soil; citric acid can decrease the adsorption of both lead and cadmium. Dietary citric acid can effectively improve phytate P utilization in chicks.
    CFN98449 Chelerythrine

    Chelerythrine is a well-known protein kinase C inhibitor, can inhibit telomerase activity, it also can block the human P2X 7 receptor. Chelerythrine has antimanic, potential antiproliferative and antitumor effects, it has significant cytotoxic effect, independent of p53 and androgen status, on human prostate cancer cell lines.
    CFN98259 Sanguinarine

    Sanguinarine possesses anticancer, antimicrobial, anti-inflammatory, and antioxidant properties, it has therapeutic potential in preventing the neurodegenerative diseases, it may be used to develop a potential therapeutic drug for treating cardiac remodeling and heart failure and shows protective effects on teeth and alveolar bone health. Sanguinarine can inhibit osteoclast formation and bone resorption via suppressing RANKL-induced activation of NF-κB and ERK signaling pathways, and can protect against cardiac hypertrophy and fibrosis via inhibiting NF-κB activation.
    CFN99563 Coptisine

    Coptisine is an efficient uncompetitive IDO inhibitor with a Ki value of 5.8 μM and an IC50 value of 6.3 μM, it can consequently prevent neuron loss, reduce amyloid plaque formation, and ameliorate impaired cognition, it could as a potential new class of drugs for AD treatment. Coptisine has cardioprotection, anti- hypercholesterolemia, anti-fungal, anti-osteosarcoma, anti-hepatoma and anti-leukaemia activities, it also has antispasmodic and relaxant activity on a guinea-pig ileum.
    CFN98608 8-Acetonyldihydrosanguinarine

    CFN98049 Berberine

    Berberine has neuroprotective, antidepressant, antineoplastic, and anti- fibrosis activities; it is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism, it may as a broad-spectrum anti-microbial medicine, a complementary therapeutic agent for HIV/AIDS; it also may be one of the targeted therapeutic agents that can restore barrier function in intestinal disease states.Berberine is used in histology for staining heparin in mast cells. As a natural dye, berberine has a colour index of 75160.
    CFN97999 Oxychelerythrine

    Oxychelerythrine shows high modulatory activity enhancing the susceptibility of the S. aureus ATCC 6538 to all the tested antibiotics from two to four-fold. It also shows antifeeding activities against Tribolium castaneum adults, with the EC50 of 192.32 ppm. enhancing the susceptibility of the S. aureus ATCC 6538 to all the tested antibiotics from two to four-fold.