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  • Bioactive Products
    Antihyperglycemic Compound Library
    A unique collection of 73 Antihyperglycemic natural compounds for high throughput screening (HTS) and high content screening (HCS).
    Catalog No: B545 Antihyperglycemic Compound Library
    Screening Details
    Size: 1mg/well * 73 Compounds
    2mg/well * 73 Compounds
    Catalog No. Information
    CFN99044 D-Pinitol

    D-Pinitol is a safe nutrient to reduce calorie consumption when supplementing with creatine. It exerts anti-inflammatory, insulin-like activities; and inhibits osteoclastogenesis from bone marrow stromal cells and macrophage cells, which in turn protect bone loss from ovariectomy. It inhibits the activation of p38, JNK, and NF-κB, the expression of p53, Bcl-2, Bax and NF-kB proteins, and reduces focal adhesion kinase (FAK) phosphorylation, c-Src kinase activity.
    CFN99394 Paulownin

    1. (+)-Paulownin is active against the MCF-7 breast cancer cell line with IC50 values of 14.0 uM.
    2. Paulownin has the action of anti-inflammation,analgesia,immunity,hypoglycemia and has little toxicity.
    3. Paulownin demonstrates inhibitory activities against H. pylori Cystathionine gamma- synthase (HpCGS) with IC50 values of 19 +/- 2 microM, it can highly inhibit the growth of H. pylori and exhibit strong inhibitory specificity against H. pylori related to E. coli.
    CFN99113 Fraxetin

    Fraxetin has dual-antioxidative ,hepatoprotective and antihyperglycemic functions, it shows potent protective effects against CCl4 induced oxidative stress and hepatic fibrosis, has a marked inhibitory effect on S.aureus proliferation. It increased the level of Nrf2/ARE, and HO-1, inhibit the formation of ROS, cytochrome c release, activation of caspase-3 and 9, and suppressed the up-regulation of Bax.
    CFN99116 Chlorogenic acid

    Chlorogenic acid, a phenolic compound found ubiquitously in plants, is an antioxidant and metal chelator, it has antiviral activity by inhibiting HBV replication, it inhibits the inflammatory reaction in HSE via the suppression of TLR2/TLR9-Myd88 signaling pathways. Some derivatives of chlorogenic acid are hypoglycemic agents and may affect lipid metabolism, chlorogenic acid can improve glucose tolerance, decrease some plasma and liver lipids, and improve mineral pool distribution in vivo.
    CFN99124 Palmatine hydrochloride

    Palmatine hydrochloride is a hydrochloride salt of palmatine which is a protoberberine alkaloid, it can induce remarkable cell apoptosis, has potential in photodynamic therapy on colon adenocarcinoma. Palmatine hydrochloride has anti-C. albicans effect, it mixes with berberine hydrochloride elicit antifungal activities, it also can reduce blood sugar and oxidative stress in STZ induced diabetic rats.